[Term]
id: PR:000027494
name: interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (human)
def: "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P51617-1, Thr-209, MOD:00047." [PRO:DNx, UniProtKB:P51617]
comment: Category=organism-modification.
synonym: "hIRAK1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P51617-1, Thr-209, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000021975 ! interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000027492
name: interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 (human)
def: "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047." [PMID:14625308, PRO:CNA]
comment: Category=organism-modification.
synonym: "pp-IRAK1 (human)" EXACT []
synonym: "hIRAK1/iso:1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000021977 ! interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000027493
name: interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human)
def: "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA]
comment: Category=organism-modification.
synonym: "hp-IRAK1 (human)" EXACT []
synonym: "hIRAK1/iso:1/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000021978 ! interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000048042
name: interleukin-1 receptor-associated kinase 1 phosphorylated 5 (human)
def: "An interleukin-1 receptor-associated kinase 1 (human) that has been post-translationally modified to include phosphoserine at position 376, and phosphothreonine at position 387 of the amino acid sequence represented by UniProtKB:P51617. UniProtKB:P51617, Ser-376, MOD:00046|Thr-387, MOD:00047." [PRO:DNx, Reactome:R-HSA-446687]
comment: Category=organism-modification.
synonym: "hIRAK1/Phos:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P51617, Ser-376, MOD:00046|Thr-387, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-446687 "PR:000048042 located_in GO:0005829"
is_a: PR:P51617 ! interleukin-1 receptor-associated kinase 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048043
name: interleukin-1 receptor-associated kinase 1 phosphorylated 1 (human)
def: "An interleukin-1 receptor-associated kinase 1 (human) that has been post-translationally modified to include phosphothreonine at position 209 of the amino acid sequence represented by UniProtKB:P51617. UniProtKB:P51617, Thr-209, MOD:00047." [PRO:DNx, Reactome:R-HSA-937031, Reactome:R-HSA-975189]
comment: Category=organism-modification.
synonym: "hIRAK1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P51617, Thr-209, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-937031 "PR:000048043 located_in GO:0005886"
xref: Reactome:R-HSA-975189 "PR:000048043 located_in GO:0010008"
is_a: PR:P51617 ! interleukin-1 receptor-associated kinase 1 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048044
name: interleukin-1 receptor-associated kinase 1 phosphorylated 3 (human)
def: "An interleukin-1 receptor-associated kinase 1 (human) that has been post-translationally modified to include phosphothreonine at positions 209 and 387 of the amino acid sequence represented by UniProtKB:P51617. UniProtKB:P51617, Thr-209/Thr-387, MOD:00047." [PRO:DNx, Reactome:R-HSA-166279, Reactome:R-HSA-975117]
comment: Category=organism-modification.
synonym: "hIRAK1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P51617, Thr-209/Thr-387, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-166279 "PR:000048044 located_in GO:0005886"
xref: Reactome:R-HSA-975117 "PR:000048044 located_in GO:0010008"
is_a: PR:P51617 ! interleukin-1 receptor-associated kinase 1 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P51617-1
name: interleukin-1 receptor-associated kinase 1 isoform 1 (human)
def: "An interleukin-1 receptor-associated kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hIRAK1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "interleukin-1 receptor-associated kinase 1 isoform a (human)" EXACT [UniProtKB:P51617]
xref: UniProtKB:P51617-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000021973 ! interleukin-1 receptor-associated kinase 1 isoform 1

[Term]
id: PR:P51617-2
name: interleukin-1 receptor-associated kinase 1 isoform h2 (human)
def: "An interleukin-1 receptor-associated kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51617-2." [PRO:DNx, UniProtKB:P51617]
comment: Category=organism-sequence.
synonym: "hIRAK1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "interleukin-1 receptor-associated kinase 1 isoform b (human)" EXACT [UniProtKB:P51617]
xref: UniProtKB:P51617-2
is_a: PR:P51617 ! interleukin-1 receptor-associated kinase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P51617-3
name: interleukin-1 receptor-associated kinase 1 isoform h3 (human)
def: "An interleukin-1 receptor-associated kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51617-3." [PRO:DNx, UniProtKB:P51617]
comment: Category=organism-sequence.
synonym: "hIRAK1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P51617-3
is_a: PR:P51617 ! interleukin-1 receptor-associated kinase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P51617-4
name: interleukin-1 receptor-associated kinase 1 isoform h4 (human)
def: "An interleukin-1 receptor-associated kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51617-4." [PRO:DNx, UniProtKB:P51617]
comment: Category=organism-sequence.
synonym: "hIRAK1/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P51617-4
is_a: PR:P51617 ! interleukin-1 receptor-associated kinase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P51617
name: interleukin-1 receptor-associated kinase 1 (human)
def: "An interleukin-1 receptor-associated kinase 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-gene.
synonym: "IRAK" RELATED Gene-based [UniProtKB:P51617]
synonym: "IRAK1" RELATED Gene-based [UniProtKB:P51617]
synonym: "hIRAK1" EXACT PRO-short-label [PRO:DNx]
synonym: "IRAK-1 (human)" EXACT [UniProtKB:P51617]
xref: Reactome:R-HSA-937045 "PR:P51617 located_in GO:0005886"
xref: Reactome:R-HSA-975127 "PR:P51617 located_in GO:0010008"
xref: Reactome:R-HSA-446639 "PR:P51617 located_in GO:0005829"
xref: DTO:03100190
xref: UniProtKB:P51617
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001782 ! interleukin-1 receptor-associated kinase 1
relationship: has_gene_template HGNC:6112 ! IRAK1 (human)

[Term]
id: PR:000001782
name: interleukin-1 receptor-associated kinase 1
def: "An interleukin-1 receptor-associated kinase IRAK1/3 that is a translation product of the human IRAK1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "IRAK" RELATED Gene-based []
synonym: "IRAK1" EXACT PRO-short-label [PRO:DNx]
synonym: "IRAK-1" EXACT []
synonym: "Il1rak" RELATED Gene-based []
xref: IUPHARobj:2042
is_a: PR:000001781 ! interleukin-1 receptor-associated kinase IRAK1/3