[Term]
id: PR:O88351
name: inhibitor of nuclear factor kappa-B kinase subunit beta (mouse)
def: "An inhibitor of nuclear factor kappa-B kinase subunit beta that is encoded in the genome of mouse." [OMA:O88351, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ikkb" RELATED Gene-based [UniProtKB:O88351]
synonym: "Ikbkb" RELATED Gene-based [UniProtKB:O88351]
synonym: "mIKBKB" EXACT PRO-short-label [PRO:DNx]
synonym: "IKK2 (mouse)" EXACT [UniProtKB:O88351]
synonym: "IKK-B (mouse)" EXACT [UniProtKB:O88351]
synonym: "IkBKB (mouse)" EXACT [UniProtKB:O88351]
synonym: "NFKBIKB (mouse)" EXACT [UniProtKB:O88351]
synonym: "IKK-beta (mouse)" EXACT [UniProtKB:O88351]
synonym: "I-kappa-B kinase 2 (mouse)" EXACT [UniProtKB:O88351]
synonym: "I-kappa-B-kinase beta (mouse)" EXACT [UniProtKB:O88351]
synonym: "serine/threonine protein kinase IKBKB (mouse)" EXACT [UniProtKB:O88351]
synonym: "nuclear factor NF-kappa-B inhibitor kinase beta (mouse)" EXACT [UniProtKB:O88351]
xref: UniProtKB:O88351
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001776 ! inhibitor of nuclear factor kappa-B kinase subunit beta
relationship: has_gene_template MGI:1338071 ! Ikbkb (mouse)

[Term]
id: PR:000036115
name: inhibitor of nuclear factor kappa-B kinase subunit beta phosphorylated 1 (mouse)
def: "An inhibitor of nuclear factor kappa-B kinase subunit beta phosphorylated 1 in mouse. Phosphorylation is necessary for activation, and occurs on two Ser residues in the activation loop. UniProtKB:O88351, Ser-177/Ser-181, MOD:00046." [PMID:16751795, PMID:18202307, PRO:CNA, PRO:DAN]
comment: Category=organism-modification.
synonym: "mIKBKB/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-S177,S181-IKK beta (mouse)" EXACT []
synonym: "UniProtKB:O88351, Ser-177/Ser-181, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000035830 ! inhibitor of nuclear factor kappa-B kinase subunit beta phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000001776
name: inhibitor of nuclear factor kappa-B kinase subunit beta
def: "An inhibitor of nuclear factor kappa-B kinase complex alpha/beta subunits that is a translation product of the human IKBKB gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "IKK2" EXACT []
synonym: "IKKB" RELATED Gene-based []
synonym: "IKBKB" EXACT PRO-short-label [PRO:DNx]
synonym: "IKK-B" EXACT []
synonym: "IkBKB" EXACT []
synonym: "NFKBIKB" EXACT []
synonym: "IKK-beta" EXACT []
synonym: "I-kappa-B kinase 2" EXACT []
synonym: "I-kappa-B-kinase beta" EXACT []
synonym: "serine/threonine protein kinase IKBKB" EXACT []
synonym: "nuclear factor NF-kappa-B inhibitor kinase beta" EXACT []
xref: IUPHARobj:2039
is_a: PR:000001774 ! inhibitor of nuclear factor kappa-B kinase complex alpha/beta subunits