[Term]
id: PR:Q60680-3
name: inhibitor of nuclear factor kappa-B kinase subunit alpha isoform m3 (mouse)
def: "An inhibitor of nuclear factor kappa-B kinase subunit alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q60680-3." [PRO:DNx, UniProtKB:Q60680]
comment: Category=organism-sequence.
synonym: "mCHUK/iso:m3" EXACT PRO-short-label [PRO:DNx]
synonym: "inhibitor of nuclear factor kappa-B kinase subunit alpha isoform Delta H (mouse)" EXACT [UniProtKB:Q60680]
xref: UniProtKB:Q60680-3
is_a: PR:Q60680 ! inhibitor of nuclear factor kappa-B kinase subunit alpha (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q60680-2
name: inhibitor of nuclear factor kappa-B kinase subunit alpha isoform m2 (mouse)
def: "An inhibitor of nuclear factor kappa-B kinase subunit alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q60680-2." [PRO:DNx, UniProtKB:Q60680]
comment: Category=organism-sequence.
synonym: "mCHUK/iso:m2" EXACT PRO-short-label [PRO:DNx]
synonym: "inhibitor of nuclear factor kappa-B kinase subunit alpha isoform Delta LH (mouse)" EXACT [UniProtKB:Q60680]
xref: UniProtKB:Q60680-2
is_a: PR:Q60680 ! inhibitor of nuclear factor kappa-B kinase subunit alpha (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q60680-1
name: inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 (mouse)
def: "An inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 that is encoded in the genome of mouse." [PRO:CNx]
comment: Category=organism-sequence.
synonym: "mCHUK/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q60680-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000026820 ! inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1

[Term]
id: PR:000036121
name: inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 phosphorylated 1 (mouse)
def: "An inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 phosphorylated 1 in mouse. UniProtKB:Q60680-1, Ser-176/Ser-180, MOD:00046." [PMID:16751795, PRO:CNA]
comment: Category=organism-modification. Requested by=TLR.
synonym: "mCHUK/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "phospho-IKK1 (mouse)" EXACT []
synonym: "UniProtKB:Q60680-1, Ser-176/Ser-180, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000026822 ! inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000001775
name: inhibitor of nuclear factor kappa-B kinase subunit alpha
def: "An inhibitor of nuclear factor kappa-B kinase complex alpha/beta subunits that is a translation product of the human CHUK gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "CHUK" EXACT PRO-short-label [PRO:DNx]
synonym: "IKK1" EXACT []
synonym: "IKKA" RELATED Gene-based []
synonym: "IKK-A" EXACT []
synonym: "IkBKA" EXACT []
synonym: "TCF16" RELATED Gene-based []
synonym: "TCF-16" EXACT []
synonym: "NFKBIKA" EXACT []
synonym: "IKK-alpha" EXACT []
synonym: "IkappaB kinase" EXACT []
synonym: "I-kappa-B kinase 1" EXACT []
synonym: "I-kappa-B kinase alpha" EXACT []
synonym: "transcription factor 16" EXACT []
synonym: "conserved helix-loop-helix ubiquitous kinase" EXACT []
synonym: "nuclear factor NF-kappa-B inhibitor kinase alpha" EXACT []
xref: IUPHARobj:1989
is_a: PR:000001774 ! inhibitor of nuclear factor kappa-B kinase complex alpha/beta subunits

[Term]
id: PR:Q60680
name: inhibitor of nuclear factor kappa-B kinase subunit alpha (mouse)
def: "An inhibitor of nuclear factor kappa-B kinase subunit alpha that is encoded in the genome of mouse." [OMA:Q60680, PRO:DNx]
comment: Category=organism-gene.
synonym: "Chuk" RELATED Gene-based [UniProtKB:Q60680]
synonym: "Ikka" RELATED Gene-based [UniProtKB:Q60680]
synonym: "mCHUK" EXACT PRO-short-label [PRO:DNx]
synonym: "IKK1 (mouse)" EXACT [UniProtKB:Q60680]
synonym: "IKK-A (mouse)" EXACT [UniProtKB:Q60680]
synonym: "IkBKA (mouse)" EXACT [UniProtKB:Q60680]
synonym: "NFKBIKA (mouse)" EXACT [UniProtKB:Q60680]
synonym: "IKK-alpha (mouse)" EXACT [UniProtKB:Q60680]
synonym: "IkappaB kinase (mouse)" EXACT [UniProtKB:Q60680]
synonym: "I-kappa-B kinase 1 (mouse)" EXACT [UniProtKB:Q60680]
synonym: "I-kappa-B kinase alpha (mouse)" EXACT [UniProtKB:Q60680]
synonym: "conserved helix-loop-helix ubiquitous kinase (mouse)" EXACT [UniProtKB:Q60680]
synonym: "nuclear factor NF-kappa-B inhibitor kinase alpha (mouse)" EXACT [UniProtKB:Q60680]
xref: UniProtKB:Q60680
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001775 ! inhibitor of nuclear factor kappa-B kinase subunit alpha
relationship: has_gene_template MGI:99484 ! Chuk (mouse)