[Term]
id: PR:000001740
name: myeloid differentiation primary response protein MyD88
def: "A protein that is a translation product of the human MYD88 gene or a 1:1 ortholog thereof. This protein is an adapter involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response." [PMID:9575168, PRO:CNA]
comment: Category=gene.
synonym: "MYD88" EXACT PRO-short-label [PRO:DNx]
xref: PIRSF:PIRSF037756
is_a: PR:000000001 ! protein

[Term]
id: PR:A5HNF6
name: myeloid differentiation primary response protein MyD88 (chicken)
def: "A myeloid differentiation primary response protein MyD88 that is encoded in the genome of chicken." [OMA:A5HNF6, PMID:18582498, PRO:CNA]
comment: Category=organism-gene. Note: The chicken MyD88 gene was cloned and its expression was detected in cecum, heart, spleen, liver, kidney, female reproductive tract, thymus and bursa. Over-expression of chicken MyD88 significantly stimulated the activation of NF-kB in vitro.
synonym: "MYD88" RELATED Gene-based [UniProtKB:A5HNF6]
synonym: "chick-MYD88" EXACT PRO-short-label [PRO:DNx]
synonym: "RCJMB04_14h3" RELATED Gene-based [UniProtKB:A5HNF6]
xref: UniProtKB:A5HNF6
xref: Reactome:R-GGA-433900 "PR:A5HNF6 located_in GO:0005886"
xref: Reactome:R-GGA-433987 "PR:A5HNF6 located_in GO:0005829"
xref: Reactome:R-GGA-573258 "PR:A5HNF6 located_in GO:0010008"
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000001740 ! myeloid differentiation primary response protein MyD88
relationship: has_gene_template CGNC:4445 ! MYD88 (chicken)