[Term]
id: PR:000001677
name: thyrotropin receptor
def: "A glycoprotein hormone receptor that is a translation product of the human TSHR gene or a 1:1 ortholog thereof. The preferred ligand is thyrotropin (thyroid-stimulating hormone)." [PRO:WCB]
comment: Category=gene.
synonym: "LGR3" RELATED Gene-based []
synonym: "TSHR" EXACT PRO-short-label [PRO:DNx]
synonym: "TSH-R" EXACT []
synonym: "thyroid-stimulating hormone receptor" EXACT []
xref: IUPHARobj:255
is_a: PR:000001463 ! glycoprotein hormone receptor

[Term]
id: PR:P16473
name: thyrotropin receptor (human)
def: "A thyrotropin receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:P16473]
comment: Category=organism-gene.
synonym: "LGR3" RELATED Gene-based [UniProtKB:P16473]
synonym: "TSHR" RELATED Gene-based [UniProtKB:P16473]
synonym: "hTSHR" EXACT PRO-short-label [PRO:DNx]
synonym: "TSH-R (human)" EXACT [UniProtKB:P16473]
synonym: "thyroid-stimulating hormone receptor (human)" EXACT [UniProtKB:P16473]
xref: DTO:02100813
xref: UniProtKB:P16473
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001677 ! thyrotropin receptor
relationship: has_gene_template HGNC:12373 ! TSHR (human)

[Term]
id: PR:000049558
name: thyrotropin receptor, signal peptide removed form (human)
def: "A thyrotropin receptor (human) that has had the signal peptide removed. UniProtKB:P16473, 21-764." [PRO:DNx, Reactome:R-HSA-391371]
comment: Category=organism-modification.
synonym: "hTSHR/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000012786" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P16473, 21-764" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-391371 "PR:000049558 located_in GO:0005886"
intersection_of: PR:P16473 ! thyrotropin receptor (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P16473-1
name: thyrotropin receptor isoform Long (human)
def: "A thyrotropin receptor isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hTSHR/iso:Long" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16473-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038957 ! thyrotropin receptor isoform 1

[Term]
id: PR:P16473-3
name: thyrotropin receptor isoform h3 (human)
def: "A thyrotropin receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16473-3." [PRO:DNx, UniProtKB:P16473]
comment: Category=organism-sequence.
synonym: "hTSHR/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16473-3
is_a: PR:P16473 ! thyrotropin receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P16473-2
name: thyrotropin receptor isoform Short (human)
def: "A thyrotropin receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16473-2." [PRO:DNx, UniProtKB:P16473]
comment: Category=organism-sequence.
synonym: "hTSHR/iso:Short" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16473-2
is_a: PR:P16473 ! thyrotropin receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens