[Term]
id: PR:000001664
name: proteinase-activated receptor 4
def: "A proteinase-activated receptor that is a translation product of the human F2RL3 gene or a 1:1 ortholog thereof. It is activated by thrombin and cathepsin G, which cleave the mature peptide, exposing a new amino end. The six new N-terminal residues act as a tethered ligand that induces activity." [PMID:10702240, PMID:9618465, PRO:WCB]
comment: Category=gene.
synonym: "PAR4" RELATED Gene-based []
synonym: "F2RL3" EXACT PRO-short-label [PRO:DNx]
synonym: "PAR-4" EXACT []
synonym: "thrombin receptor-like 3" EXACT []
synonym: "coagulation factor II receptor-like 3" EXACT []
xref: IUPHARobj:350
is_a: PR:000001550 ! proteinase-activated receptor