[Term]
id: PR:000001663
name: proteinase-activated receptor 3
def: "A proteinase-activated receptor that is a translation product of the human F2RL2 gene or a 1:1 ortholog thereof. It is activated by thrombin, which cleaves the mature peptide, exposing a new amino end. The six new N-terminal residues act as a tethered ligand that induces activity." [PMID:15582715, PRO:WCB]
comment: Category=gene.
synonym: "PAR3" RELATED Gene-based []
synonym: "F2RL2" EXACT PRO-short-label [PRO:DNx]
synonym: "PAR-3" RELATED []
synonym: "thrombin receptor-like 2" EXACT []
synonym: "coagulation factor II receptor-like 2" EXACT []
xref: IUPHARobj:349
is_a: PR:000001550 ! proteinase-activated receptor