[Term]
id: PR:000001662
name: proteinase-activated receptor 2
def: "A proteinase-activated receptor that is a translation product of the human F2RL1 gene or a 1:1 ortholog thereof. It is activated by trypsin and trypsin-like proteinases, which cleave the mature peptide, exposing a new amino end. The six new N-terminal residues act as a tethered ligand that induces activity." [PMID:7556175, PRO:WCB]
comment: Category=gene.
synonym: "PAR2" RELATED Gene-based []
synonym: "F2RL1" EXACT PRO-short-label [PRO:DNx]
synonym: "GPR11" RELATED Gene-based []
synonym: "PAR-2" EXACT []
synonym: "Gpcr11" RELATED Gene-based []
synonym: "thrombin receptor-like 1" EXACT []
synonym: "G-protein coupled receptor 11" EXACT []
synonym: "coagulation factor II receptor-like 1" EXACT []
xref: IUPHARobj:348
is_a: PR:000001550 ! proteinase-activated receptor

[Term]
id: PR:P55086
name: proteinase-activated receptor 2 (mouse)
def: "A proteinase-activated receptor 2 that is encoded in the genome of mouse." [OMA:P55086, PRO:DNx]
comment: Category=organism-gene.
synonym: "Par2" RELATED Gene-based [UniProtKB:P55086]
synonym: "F2rl1" RELATED Gene-based [UniProtKB:P55086]
synonym: "Gpr11" RELATED Gene-based [UniProtKB:P55086]
synonym: "Gpcr11" RELATED Gene-based [UniProtKB:P55086]
synonym: "mF2RL1" EXACT PRO-short-label [PRO:DNx]
synonym: "PAR-2 (mouse)" EXACT [UniProtKB:P55086]
synonym: "thrombin receptor-like 1 (mouse)" EXACT [UniProtKB:P55086]
synonym: "G-protein coupled receptor 11 (mouse)" EXACT [UniProtKB:P55086]
synonym: "coagulation factor II receptor-like 1 (mouse)" EXACT [UniProtKB:P55086]
xref: UniProtKB:P55086
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001662 ! proteinase-activated receptor 2
relationship: has_gene_template MGI:101910 ! F2rl1 (mouse)