[Term]
id: PR:P43115-6
name: prostaglandin E2 receptor EP3 subtype isoform hEP3F (human)
def: "A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-6." [PRO:DNx, UniProtKB:P43115]
comment: Category=organism-sequence.
synonym: "hPTGER3/iso:hEP3F" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43115-6
is_a: PR:P43115 ! prostaglandin E2 receptor EP3 subtype (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43115-7
name: prostaglandin E2 receptor EP3 subtype isoform hEP3G (human)
def: "A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-7." [PRO:DNx, UniProtKB:P43115]
comment: Category=organism-sequence.
synonym: "hPTGER3/iso:hEP3G" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43115-7
is_a: PR:P43115 ! prostaglandin E2 receptor EP3 subtype (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43115-4
name: prostaglandin E2 receptor EP3 subtype isoform hEP3D (human)
def: "A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-4." [PRO:DNx, UniProtKB:P43115]
comment: Category=organism-sequence.
synonym: "hPTGER3/iso:hEP3D" EXACT PRO-short-label [PRO:DNx]
synonym: "prostaglandin E2 receptor EP3 subtype isoform EP3-IV (human)" BROAD [UniProtKB:P43115]
xref: UniProtKB:P43115-4
is_a: PR:P43115 ! prostaglandin E2 receptor EP3 subtype (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43115-5
name: prostaglandin E2 receptor EP3 subtype isoform hEP3E (human)
def: "A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-5." [PRO:DNx, UniProtKB:P43115]
comment: Category=organism-sequence.
synonym: "hPTGER3/iso:hEP3E" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43115-5
is_a: PR:P43115 ! prostaglandin E2 receptor EP3 subtype (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43115-2
name: prostaglandin E2 receptor EP3 subtype isoform hEP3C (human)
def: "A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-2." [PRO:DNx, UniProtKB:P43115]
comment: Category=organism-sequence.
synonym: "hPTGER3/iso:hEP3C" EXACT PRO-short-label [PRO:DNx]
synonym: "prostaglandin E2 receptor EP3 subtype isoform EP3-II (human)" EXACT [UniProtKB:P43115]
xref: UniProtKB:P43115-2
is_a: PR:P43115 ! prostaglandin E2 receptor EP3 subtype (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43115-3
name: prostaglandin E2 receptor EP3 subtype isoform hEP3B (human)
def: "A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-3." [PRO:DNx, UniProtKB:P43115]
comment: Category=organism-sequence.
synonym: "hPTGER3/iso:hEP3B" EXACT PRO-short-label [PRO:DNx]
synonym: "prostaglandin E2 receptor EP3 subtype isoform EP3-III (human)" BROAD [UniProtKB:P43115]
xref: UniProtKB:P43115-3
is_a: PR:P43115 ! prostaglandin E2 receptor EP3 subtype (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43115-1
name: prostaglandin E2 receptor EP3 subtype isoform hEP3A (human)
def: "A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-1." [PRO:DNx, UniProtKB:P43115]
comment: Category=organism-sequence.
synonym: "hPTGER3/iso:hEP3A" EXACT PRO-short-label [PRO:DNx]
synonym: "prostaglandin E2 receptor EP3 subtype isoform EP3-I (human)" EXACT [UniProtKB:P43115]
synonym: "prostaglandin E2 receptor EP3 subtype isoform EP3a1 (human)" EXACT [UniProtKB:P43115]
synonym: "prostaglandin E2 receptor EP3 subtype isoform EP3a2 (human)" EXACT [UniProtKB:P43115]
synonym: "prostaglandin E2 receptor EP3 subtype isoform EP(3-Ic) (human)" EXACT [UniProtKB:P43115]
xref: UniProtKB:P43115-1
is_a: PR:P43115 ! prostaglandin E2 receptor EP3 subtype (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43115-8
name: prostaglandin E2 receptor EP3 subtype isoform hEP3-III (human)
def: "A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-8." [PRO:DNx, UniProtKB:P43115]
comment: Category=organism-sequence.
synonym: "hPTGER3/iso:hEP3-III" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43115-8
is_a: PR:P43115 ! prostaglandin E2 receptor EP3 subtype (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43115
name: prostaglandin E2 receptor EP3 subtype (human)
def: "A prostaglandin E2 receptor EP3 subtype that is encoded in the genome of human." [PRO:WCB, UniProtKB:P43115]
comment: Category=organism-gene.
synonym: "PTGER3" RELATED Gene-based [UniProtKB:P43115]
synonym: "hPTGER3" EXACT PRO-short-label [PRO:DNx]
synonym: "PGE2-R (human)" EXACT [UniProtKB:P43115]
synonym: "prostanoid EP3 receptor (human)" EXACT [UniProtKB:P43115]
synonym: "PGE receptor EP3 subtype (human)" EXACT [UniProtKB:P43115]
synonym: "PGE2 receptor EP3 subtype (human)" EXACT [UniProtKB:P43115]
xref: Reactome:R-HSA-391828 "PR:P43115 located_in GO:0005886"
xref: DTO:02100745
xref: UniProtKB:P43115
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001659 ! prostaglandin E2 receptor EP3 subtype
relationship: has_gene_template HGNC:9595 ! PTGER3 (human)

[Term]
id: PR:000001659
name: prostaglandin E2 receptor EP3 subtype
def: "A prostanoid receptor that is a translation product of the human PTGER3 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is the most ubiquitous of the prostaglandin E2 receptors, mediating contraction of gastrointestinal, uterine, and vascular smooth muscle, inhibition of neurotransmitter release from autonomic nerves, inhibition of lipolysis in adipocytes, inhibition of acid secretion from gastric mucosa, and inhibition of water reabsorption in kidney." [PMID:7938166, PRO:WCB]
comment: Category=gene.
synonym: "PGE2-R" EXACT []
synonym: "PTGER3" EXACT PRO-short-label [PRO:DNx]
synonym: "Ptgerep3" RELATED Gene-based []
synonym: "prostanoid EP3 receptor" EXACT []
synonym: "PGE receptor EP3 subtype" EXACT []
synonym: "PGE2 receptor EP3 subtype" EXACT []
synonym: "prostaglandin E2 receptor EP3" EXACT []
xref: IUPHARobj:342
is_a: PR:000001549 ! prostanoid receptor

[Term]
id: PR:P43115-10
name: prostaglandin E2 receptor EP3 subtype isoform hEP3-V (human)
def: "A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-10." [PRO:DNx, UniProtKB:P43115]
comment: Category=organism-sequence.
synonym: "hPTGER3/iso:hEP3-V" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43115-10
is_a: PR:P43115 ! prostaglandin E2 receptor EP3 subtype (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43115-11
name: prostaglandin E2 receptor EP3 subtype isoform hEP3E2 (human)
def: "A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-11." [PRO:DNx, UniProtKB:P43115]
comment: Category=organism-sequence.
synonym: "hPTGER3/iso:hEP3E2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43115-11
is_a: PR:P43115 ! prostaglandin E2 receptor EP3 subtype (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43115-12
name: prostaglandin E2 receptor EP3 subtype isoform h12 (human)
def: "A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-12." [PRO:DNx, UniProtKB:P43115]
comment: Category=organism-sequence.
synonym: "hPTGER3/iso:h12" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43115-12
is_a: PR:P43115 ! prostaglandin E2 receptor EP3 subtype (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43115-9
name: prostaglandin E2 receptor EP3 subtype isoform hEP3-IV (human)
def: "A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-9." [PRO:DNx, UniProtKB:P43115]
comment: Category=organism-sequence.
synonym: "hPTGER3/iso:hEP3-IV" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43115-9
is_a: PR:P43115 ! prostaglandin E2 receptor EP3 subtype (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens