[Term]
id: PR:000047939
name: ICOS ligand, signal peptide removed form (human)
def: "An ICOS ligand (human) that has had the signal peptide removed. UniProtKB:O75144, 19-302." [PRO:DNx, Reactome:R-HSA-197910]
comment: Category=organism-modification.
synonym: "PRO_0000014803" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hICOSLG/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O75144, 19-302" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-197910 "PR:000047939 located_in GO:0005886"
intersection_of: PR:O75144 ! ICOS ligand (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000050819
name: ICOS ligand N-glycosylated 1 (human)
def: "An ICOS ligand (human) that has been N-glycosylated at the residue equivalent to Asn-225 of the amino acid sequence represented by UniProtKB:O75144-1, in which the glycan composition is represented by GlyTouCan:G60743GT. Example: UniProtKB:O75144-1, Asn-225, MOD:00160~GNO:G60743GT." [GlyGen:O75144-1, PMID:23345538, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hICOSLG/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O75144-1, Asn-225, MOD:00160~GNO:G60743GT" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O75144 ! ICOS ligand (human)
relationship: has_part GNO:G60743GT ! G60743GT
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000001425
name: ICOS ligand
def: "A B7-related protein that is a translation product of the human ICOSLG gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "B7H2" RELATED Gene-based []
synonym: "B7-H2" EXACT []
synonym: "B7RP1" RELATED Gene-based []
synonym: "CD275" EXACT []
synonym: "ICOSL" RELATED Gene-based []
synonym: "LICOS" EXACT []
synonym: "B7RP-1" EXACT []
synonym: "ICOSLG" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0653" RELATED Gene-based []
synonym: "B7 homolog 2" EXACT []
synonym: "B7-like protein Gl50" EXACT []
synonym: "B7-related protein 1" EXACT []
is_a: PR:000001290 ! B7-related protein

[Term]
id: PR:000050820
name: ICOS ligand N-glycosylated 2 (human)
def: "An ICOS ligand (human) that has been N-glycosylated at the residue equivalent to Asn-225 of the amino acid sequence represented by UniProtKB:O75144-1, in which the glycan composition is represented by GlyTouCan:G87139BK. Example: UniProtKB:O75144-1, Asn-225, MOD:00160~GNO:G87139BK." [GlyGen:O75144-1, PMID:23345538, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hICOSLG/NGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O75144-1, Asn-225, MOD:00160~GNO:G87139BK" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O75144 ! ICOS ligand (human)
relationship: has_part GNO:G87139BK ! G87139BK
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75144-1
name: ICOS ligand isoform h1 (human)
def: "An ICOS ligand (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75144-1." [PRO:DNx, UniProtKB:O75144]
comment: Category=organism-sequence.
synonym: "hICOSLG/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O75144-1
is_a: PR:O75144 ! ICOS ligand (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75144-2
name: ICOS ligand isoform h2 (human)
def: "An ICOS ligand (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75144-2." [PRO:DNx, UniProtKB:O75144]
comment: Category=organism-sequence.
synonym: "hICOSLG/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O75144-2
is_a: PR:O75144 ! ICOS ligand (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75144-3
name: ICOS ligand isoform h3 (human)
def: "An ICOS ligand (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75144-3." [PRO:DNx, UniProtKB:O75144]
comment: Category=organism-sequence.
synonym: "hICOSLG/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O75144-3
is_a: PR:O75144 ! ICOS ligand (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75144
name: ICOS ligand (human)
def: "An ICOS ligand that is encoded in the genome of human." [PRO:WCB, UniProtKB:O75144]
comment: Category=organism-gene.
synonym: "B7H2" RELATED Gene-based [UniProtKB:O75144]
synonym: "B7RP1" RELATED Gene-based [UniProtKB:O75144]
synonym: "ICOSL" RELATED Gene-based [UniProtKB:O75144]
synonym: "ICOSLG" RELATED Gene-based [UniProtKB:O75144]
synonym: "hICOSLG" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0653" RELATED Gene-based [UniProtKB:O75144]
synonym: "B7-H2 (human)" EXACT [UniProtKB:O75144]
synonym: "CD275 (human)" EXACT [UniProtKB:O75144]
synonym: "B7RP-1 (human)" EXACT [UniProtKB:O75144]
synonym: "B7 homolog 2 (human)" EXACT [UniProtKB:O75144]
synonym: "B7-like protein Gl50 (human)" EXACT [UniProtKB:O75144]
synonym: "B7-related protein 1 (human)" EXACT [UniProtKB:O75144]
xref: UniProtKB:O75144
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001425 ! ICOS ligand
relationship: has_gene_template HGNC:17087 ! ICOSLG (human)