[Term] id: PR:000001423 name: histamine H2 receptor def: "A histamine receptor that is a translation product of the human HRH2 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor mediates smooth muscle relaxation, gastric acid secretion, and other diverse effects." [PMID:9311023, PRO:WCB] comment: Category=gene. synonym: "H2R" EXACT [] synonym: "HH2R" EXACT [] synonym: "HRH2" EXACT PRO-short-label [PRO:DNx] synonym: "gastric receptor I" EXACT [] synonym: "H2 histamine receptor" EXACT [] xref: IUPHARobj:263 xref: PIRSF:PIRSF038634 is_a: PR:000049994 ! histamine receptor [Term] id: PR:P25102 name: histamine H2 receptor (rat) def: "A histamine H2 receptor that is encoded in the genome of rat." [OMA:P25102, PANTHER:PTHR24249:SF46, PRO:DNx] comment: Category=organism-gene. synonym: "Hrh2" RELATED Gene-based [UniProtKB:P25102] synonym: "rHRH2" EXACT PRO-short-label [PRO:DNx] synonym: "H2R (rat)" EXACT [UniProtKB:P25102] synonym: "HH2R (rat)" EXACT [UniProtKB:P25102] synonym: "gastric receptor I (rat)" EXACT [UniProtKB:P25102] xref: UniProtKB:P25102 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000001423 ! histamine H2 receptor relationship: has_gene_template RGD:2831 ! Hrh2 (rat)