[Term]
id: PR:P25021-1
name: histamine H2 receptor isoform h1 (human)
def: "A histamine H2 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P25021-1." [PRO:DNx, UniProtKB:P25021]
comment: Category=organism-sequence.
synonym: "hHRH2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P25021-1
is_a: PR:P25021 ! histamine H2 receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P25021-2
name: histamine H2 receptor isoform h2 (human)
def: "A histamine H2 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P25021-2." [PRO:DNx, UniProtKB:P25021]
comment: Category=organism-sequence.
synonym: "hHRH2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P25021-2
is_a: PR:P25021 ! histamine H2 receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000001423
name: histamine H2 receptor
def: "A histamine receptor that is a translation product of the human HRH2 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor mediates smooth muscle relaxation, gastric acid secretion, and other diverse effects." [PMID:9311023, PRO:WCB]
comment: Category=gene.
synonym: "H2R" EXACT []
synonym: "HH2R" EXACT []
synonym: "HRH2" EXACT PRO-short-label [PRO:DNx]
synonym: "gastric receptor I" EXACT []
synonym: "H2 histamine receptor" EXACT []
xref: IUPHARobj:263
xref: PIRSF:PIRSF038634
is_a: PR:000049994 ! histamine receptor

[Term]
id: PR:P25021
name: histamine H2 receptor (human)
def: "A histamine H2 receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:P25021]
comment: Category=organism-gene.
synonym: "HRH2" RELATED Gene-based [UniProtKB:P25021]
synonym: "hHRH2" EXACT PRO-short-label [PRO:DNx]
synonym: "H2R (human)" EXACT [UniProtKB:P25021]
synonym: "HH2R (human)" EXACT [UniProtKB:P25021]
synonym: "gastric receptor I (human)" EXACT [UniProtKB:P25021]
xref: Reactome:R-HSA-390907 "PR:P25021 located_in GO:0005886"
xref: DTO:02100231
xref: UniProtKB:P25021
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001423 ! histamine H2 receptor
relationship: has_gene_template HGNC:5183 ! HRH2 (human)