[Term] id: PR:000001422 name: histamine H1 receptor def: "A histamine receptor that is a translation product of the human HRH1 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Note: The preferred ligand is histamine. This receptor mediates smooth muscle contraction, NO formation, increased vascular permeability, and other diverse effects. [PMID:9311023] synonym: "H1R" EXACT [] synonym: "Bphs" RELATED Gene-based [] synonym: "HH1R" EXACT [] synonym: "HRH1" EXACT PRO-short-label [PRO:DNx] synonym: "H1 histamine receptor" EXACT [] xref: IUPHARobj:262 xref: PIRSF:PIRSF038644 is_a: PR:000049994 ! histamine receptor