[Term]
id: PR:P42081-3
name: T-lymphocyte activation antigen CD86 isoform h2 (human)
def: "A T-lymphocyte activation antigen CD86 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42081-3." [PRO:DNx, UniProtKB:P42081]
comment: Category=organism-sequence.
synonym: "hCD86/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42081-3
is_a: PR:P42081 ! T-lymphocyte activation antigen CD86 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P42081-2
name: T-lymphocyte activation antigen CD86 isoform h3 (human)
def: "A T-lymphocyte activation antigen CD86 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42081-2." [PRO:DNx, UniProtKB:P42081]
comment: Category=organism-sequence.
synonym: "hCD86/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "T-lymphocyte activation antigen CD86 isoform CD86 deltaEC (human)" EXACT [UniProtKB:P42081]
xref: UniProtKB:P42081-2
is_a: PR:P42081 ! T-lymphocyte activation antigen CD86 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P42081-1
name: T-lymphocyte activation antigen CD86 isoform h1 (human)
def: "A T-lymphocyte activation antigen CD86 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42081-1." [PRO:DNx, UniProtKB:P42081]
comment: Category=organism-sequence.
synonym: "hCD86/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42081-1
is_a: PR:P42081 ! T-lymphocyte activation antigen CD86 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046652
name: T-lymphocyte activation antigen CD86, signal peptide removed form (human)
def: "A T-lymphocyte activation antigen CD86 (human) that has had the signal peptide removed. UniProtKB:P42081, 24-329." [PRO:DNx, Reactome:R-HSA-179784]
comment: Category=organism-modification.
synonym: "hCD86/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000014550" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P42081, 24-329" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-179784 "PR:000046652 located_in GO:0005886"
intersection_of: PR:P42081 ! T-lymphocyte activation antigen CD86 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P42081-5
name: T-lymphocyte activation antigen CD86 isoform h5 (human)
def: "A T-lymphocyte activation antigen CD86 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42081-5." [PRO:DNx, UniProtKB:P42081]
comment: Category=organism-sequence.
synonym: "hCD86/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42081-5
is_a: PR:P42081 ! T-lymphocyte activation antigen CD86 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P42081-4
name: T-lymphocyte activation antigen CD86 isoform h4 (human)
def: "A T-lymphocyte activation antigen CD86 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42081-4." [PRO:DNx, UniProtKB:P42081]
comment: Category=organism-sequence.
synonym: "hCD86/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "T-lymphocyte activation antigen CD86 isoform CD86 deltaTM (human)" EXACT [UniProtKB:P42081]
xref: UniProtKB:P42081-4
is_a: PR:P42081 ! T-lymphocyte activation antigen CD86 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000001412
name: CD86 molecule
def: "A B7-related protein that is a translation product of the human CD86 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "B70" EXACT []
synonym: "BU63" EXACT []
synonym: "CD86" EXACT PRO-short-label [PRO:DNx]
synonym: "ETC-1" EXACT []
synonym: "FUN-1" EXACT []
synonym: "CD28LG2" RELATED Gene-based []
synonym: "CD86 antigen" EXACT []
synonym: "activation B7-2 antigen" EXACT []
synonym: "CTLA-4 counter-receptor B7.2" EXACT []
synonym: "T-lymphocyte activation antigen CD86" EXACT []
synonym: "early T-cell costimulatory molecule 1" EXACT []
xref: IUPHARobj:2745
xref: PANTHER:PTHR25462:SF45
is_a: PR:000001290 ! B7-related protein

[Term]
id: PR:P42081
name: T-lymphocyte activation antigen CD86 (human)
def: "A CD86 molecule that is encoded in the genome of human." [PRO:WCB, UniProtKB:P42081]
comment: Category=organism-gene.
synonym: "CD86" RELATED Gene-based [UniProtKB:P42081]
synonym: "hCD86" EXACT PRO-short-label [PRO:DNx]
synonym: "CD28LG2" RELATED Gene-based [UniProtKB:P42081]
synonym: "B70 (human)" EXACT [UniProtKB:P42081]
synonym: "BU63 (human)" EXACT [UniProtKB:P42081]
synonym: "FUN-1 (human)" EXACT [UniProtKB:P42081]
synonym: "activation B7-2 antigen (human)" EXACT [UniProtKB:P42081]
synonym: "CTLA-4 counter-receptor B7.2 (human)" EXACT [UniProtKB:P42081]
xref: UniProtKB:P42081
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001412 ! CD86 molecule
relationship: has_gene_template HGNC:1705 ! CD86 (human)

[Term]
id: PR:P42081-6
name: T-lymphocyte activation antigen CD86 isoform h6 (human)
def: "A T-lymphocyte activation antigen CD86 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42081-6." [PRO:DNx, UniProtKB:P42081]
comment: Category=organism-sequence.
synonym: "hCD86/iso:h6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42081-6
is_a: PR:P42081 ! T-lymphocyte activation antigen CD86 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens