[Term]
id: PR:000048602
name: tumor necrosis factor receptor superfamily member 16, signal peptide removed form (human)
def: "A tumor necrosis factor receptor superfamily member 16 (human) that has had the signal peptide removed. UniProtKB:P08138, 29-427." [PRO:DNx, Reactome:R-HSA-193664]
comment: Category=organism-modification.
synonym: "hNGFR/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000034591" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P08138, 29-427" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-193664 "PR:000048602 located_in GO:0005886"
intersection_of: PR:P08138 ! tumor necrosis factor receptor superfamily member 16 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P08138-1
name: tumor necrosis factor receptor superfamily member 16 isoform h1 (human)
def: "A tumor necrosis factor receptor superfamily member 16 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08138-1." [PRO:DNx, UniProtKB:P08138]
comment: Category=organism-sequence.
synonym: "hNGFR/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P08138-1
is_a: PR:P08138 ! tumor necrosis factor receptor superfamily member 16 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000001405
name: tumor necrosis factor receptor superfamily member 16
def: "A death receptor that is a translation product of the human NGFR gene or a 1:1 ortholog thereof. This receptor contains an extracellular domain containing four repeats (about 40 residues long) with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain." [PRO:JAN, RefSeq:NP_002498]
comment: Category=gene.
synonym: "NGFR" EXACT PRO-short-label [PRO:DNx]
synonym: "CD271" EXACT []
synonym: "p75 ICD" EXACT []
synonym: "TNFRSF16" RELATED Gene-based []
synonym: "gp80-LNGFR" EXACT []
synonym: "NGF receptor" EXACT []
synonym: "low affinity neurotrophin receptor p75NTR" EXACT []
synonym: "low-affinity nerve growth factor receptor" EXACT []
xref: IUPHARobj:1888
xref: PIRSF:PIRSF001964
is_a: PR:000021999 ! death receptor

[Term]
id: PR:P08138
name: tumor necrosis factor receptor superfamily member 16 (human)
def: "A tumor necrosis factor receptor superfamily member 16 that is encoded in the genome of human." [PRO:JAN, UniProtKB:P08138]
comment: Category=organism-gene.
synonym: "NGFR" RELATED Gene-based [UniProtKB:P08138]
synonym: "hNGFR" EXACT PRO-short-label [PRO:DNx]
synonym: "TNFRSF16" RELATED Gene-based [UniProtKB:P08138]
synonym: "CD271 (human)" EXACT [UniProtKB:P08138]
synonym: "p75 ICD (human)" EXACT [UniProtKB:P08138]
synonym: "gp80-LNGFR (human)" EXACT [UniProtKB:P08138]
synonym: "NGF receptor (human)" EXACT [UniProtKB:P08138]
synonym: "low affinity neurotrophin receptor p75NTR (human)" EXACT [UniProtKB:P08138]
synonym: "low-affinity nerve growth factor receptor (human)" EXACT [UniProtKB:P08138]
xref: UniProtKB:P08138
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001405 ! tumor necrosis factor receptor superfamily member 16
relationship: has_gene_template HGNC:7809 ! NGFR (human)

[Term]
id: PR:P08138-2
name: tumor necrosis factor receptor superfamily member 16 isoform h2 (human)
def: "A tumor necrosis factor receptor superfamily member 16 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08138-2." [PRO:DNx, UniProtKB:P08138]
comment: Category=organism-sequence.
synonym: "hNGFR/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P08138-2
is_a: PR:P08138 ! tumor necrosis factor receptor superfamily member 16 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens