[Term]
id: PR:O88174
name: membrane cofactor protein (mouse)
def: "A membrane cofactor protein that is encoded in the genome of mouse." [OMA:O88174, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mcp" RELATED Gene-based [UniProtKB:O88174]
synonym: "Cd46" RELATED Gene-based [UniProtKB:O88174]
synonym: "mCD46" EXACT PRO-short-label [PRO:DNx]
synonym: "CD46 (mouse)" EXACT [UniProtKB:O88174]
xref: UniProtKB:O88174
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001401 ! membrane cofactor protein
relationship: has_gene_template MGI:1203290 ! Cd46 (mouse)

[Term]
id: PR:O88174-1
name: membrane cofactor protein isoform m1 (mouse)
def: "A membrane cofactor protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88174-1." [PRO:DNx, UniProtKB:O88174]
comment: Category=organism-sequence.
synonym: "mCD46/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O88174-1
is_a: PR:O88174 ! membrane cofactor protein (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:O88174-2
name: membrane cofactor protein isoform m2 (mouse)
def: "A membrane cofactor protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88174-2." [PRO:DNx, UniProtKB:O88174]
comment: Category=organism-sequence.
synonym: "mCD46/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O88174-2
is_a: PR:O88174 ! membrane cofactor protein (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000001401
name: membrane cofactor protein
def: "A protein that is a translation product of the human CD46 gene or a 1:1 ortholog thereof. This protein act as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue." [PRO:JAN, UniProtKB:P15529]
comment: Category=gene.
synonym: "MCP" RELATED Gene-based []
synonym: "TLX" EXACT []
synonym: "CD46" EXACT PRO-short-label [PRO:DNx]
synonym: "MIC10" RELATED Gene-based []
synonym: "trophoblast leukocyte common antigen" EXACT []
xref: PIRSF:PIRSF037971
is_a: PR:000000001 ! protein