[Term] id: PR:000048013 name: interleukin-27 subunit alpha, signal peptide removed form (human) def: "An interleukin-27 subunit alpha (human) that has had the signal peptide removed. UniProtKB:Q8NEV9, 29-243." [PRO:DNx, Reactome:R-HSA-448466] comment: Category=organism-modification. synonym: "hIL27/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000320139" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q8NEV9, 29-243" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-448466 "PR:000048013 located_in GO:0005576" xref: Reactome:R-HSA-8950430 "PR:000048013 located_in GO:0005788" xref: Reactome:R-HSA-8950553 "PR:000048013 located_in GO:0005829" intersection_of: PR:Q8NEV9 ! interleukin-27 subunit alpha (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000001385 name: interleukin-27 subunit alpha def: "A protein that is a translation product of the human IL27 gene or a 1:1 ortholog thereof. Interleukin-27 subunit alpha associates with interleukin-27 subunit beta to form interleukin-27. Interleukin-27 is a cytokine with pro- and anti-inflammatory properties." [PMID:17015723, PRO:CNA] comment: Category=gene. synonym: "p28" BROAD [PRO:DNx] synonym: "IL27" EXACT PRO-short-label [PRO:DNx] synonym: "IL30" RELATED Gene-based [] synonym: "IL-30" EXACT [] synonym: "IL27A" RELATED Gene-based [] synonym: "IL27-A" EXACT [] synonym: "IL-27-A" EXACT [] synonym: "IL27p28" EXACT [] synonym: "IL-27 subunit alpha" EXACT [] xref: PIRSF:PIRSF038755 is_a: PR:000000001 ! protein [Term] id: PR:Q8NEV9 name: interleukin-27 subunit alpha (human) def: "An interleukin-27 subunit alpha that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q8NEV9] comment: Category=organism-gene. synonym: "IL27" RELATED Gene-based [UniProtKB:Q8NEV9] synonym: "IL30" RELATED Gene-based [UniProtKB:Q8NEV9] synonym: "IL27A" RELATED Gene-based [UniProtKB:Q8NEV9] synonym: "hIL27" EXACT PRO-short-label [PRO:DNx] synonym: "p28 (human)" BROAD [UniProtKB:Q8NEV9] synonym: "IL27-A (human)" EXACT [UniProtKB:Q8NEV9] synonym: "IL-27-A (human)" EXACT [UniProtKB:Q8NEV9] synonym: "interleukin-30 (human)" EXACT [UniProtKB:Q8NEV9] synonym: "IL-27 subunit alpha (human)" EXACT [UniProtKB:Q8NEV9] xref: UniProtKB:Q8NEV9 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001385 ! interleukin-27 subunit alpha relationship: has_gene_template HGNC:19157 ! IL27 (human)