[Term] id: PR:P15509-1 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h1 (human) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-1." [PRO:DNx, UniProtKB:P15509] comment: Category=organism-sequence. synonym: "hCSF2RA/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P15509-1 is_a: PR:P15509 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000047081 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha, signal peptide removed form (human) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that has had the signal peptide removed. UniProtKB:P15509, 23-400." [PRO:DNx, Reactome:R-HSA-913361] comment: Category=organism-modification. synonym: "PRO_0000010872" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hCSF2RA/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P15509, 23-400" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-913361 "PR:000047081 located_in GO:0005886" intersection_of: PR:P15509 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P15509 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha that is encoded in the genome of human." [PRO:CNA, UniProtKB:P15509] comment: Category=organism-gene. synonym: "CSF2R" RELATED Gene-based [UniProtKB:P15509] synonym: "CSF2RA" RELATED Gene-based [UniProtKB:P15509] synonym: "CSF2RY" RELATED Gene-based [UniProtKB:P15509] synonym: "hCSF2RA" EXACT PRO-short-label [PRO:DNx] synonym: "CD116 (human)" EXACT [UniProtKB:P15509] synonym: "CDw116 (human)" EXACT [UniProtKB:P15509] synonym: "GMR-alpha (human)" EXACT [UniProtKB:P15509] synonym: "GMCSFR-alpha (human)" EXACT [UniProtKB:P15509] synonym: "GM-CSF-R-alpha (human)" EXACT [UniProtKB:P15509] xref: UniProtKB:P15509 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001354 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha relationship: has_gene_template HGNC:2435 ! CSF2RA (human) [Term] id: PR:Q00941 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha (mouse) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha that is encoded in the genome of mouse." [OMA:Q00941, PRO:DNx] comment: Category=organism-gene. synonym: "Csf2ra" RELATED Gene-based [UniProtKB:Q00941] synonym: "Csfgmra" RELATED Gene-based [UniProtKB:Q00941] synonym: "mCSF2RA" EXACT PRO-short-label [PRO:DNx] synonym: "CD116 (mouse)" EXACT [UniProtKB:Q00941] synonym: "GMR-alpha (mouse)" EXACT [UniProtKB:Q00941] synonym: "GMCSFR-alpha (mouse)" EXACT [UniProtKB:Q00941] synonym: "GM-CSF-R-alpha (mouse)" EXACT [UniProtKB:Q00941] xref: UniProtKB:Q00941 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000001354 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha relationship: has_gene_template MGI:1339754 ! Csf2ra (mouse) [Term] id: PR:Q00941-1 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 1 (mouse) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00941-1." [PMID:1533931, PRO:HJD] comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:1533931, at protein level). synonym: "mCSF2RA/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "muGM-CSFR clone 71" EXACT [PMID:1533931] synonym: "GMRalpha isoform 1 (mouse)" EXACT [] synonym: "GM-CSF receptor alpha-chain isoform 1 (mouse)" EXACT [] synonym: "GM-CSF receptor alpha subunit isoform 1 (mouse)" EXACT [] xref: UniProtKB:Q00941-1 is_a: PR:Q00941 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P15509-8 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h8 (human) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-8." [PRO:DNx, UniProtKB:P15509] comment: Category=organism-sequence. synonym: "hCSF2RA/iso:h8" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P15509-8 is_a: PR:P15509 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000001354 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha def: "A protein that is a translation product of the human CSF2RA gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. synonym: "CD116" EXACT [] synonym: "CSF2R" RELATED Gene-based [] synonym: "CDw116" EXACT [] synonym: "CSF2RA" EXACT PRO-short-label [PRO:DNx] synonym: "CSF2RY" RELATED Gene-based [] synonym: "Csfgmra" RELATED Gene-based [] synonym: "GMR-alpha" EXACT [] synonym: "GMCSFR-alpha" EXACT [] synonym: "GM-CSF-R-alpha" EXACT [] xref: IUPHARobj:1707 is_a: PR:000000001 ! protein [Term] id: PR:A9P558 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 3 (mouse) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A9P558. This isoform lacks the Fibronectin type-III (PS50853) domain and the region coding for the transmembrane domain." [GenBank:EF114318, GenPept:ABO38429, PMID:17694571, PRO:HJD] comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:17694571, at protein level). Note: PMID:17694571 shows that this isoform may be produced from a transcript where inclusion of the fifth intron into the final transcript results in a premature stop codon. synonym: "mCSF2RA/iso:3" EXACT PRO-short-label [PRO:DNx] synonym: "GMRalpha isoform 3 (mouse)" EXACT [] synonym: "GMRalpha truncated isoform (mouse)" EXACT [] synonym: "GM-CSF receptor alpha-chain isoform 3 (mouse)" EXACT [] synonym: "GM-CSF receptor alpha subunit isoform 3 (mouse)" EXACT [] xref: UniProtKB:A9P558 is_a: PR:Q00941 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P15509-2 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h2 (human) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-2." [PRO:DNx, UniProtKB:P15509] comment: Category=organism-sequence. synonym: "hCSF2RA/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P15509-2 is_a: PR:P15509 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P15509-3 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h3 (human) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-3." [PRO:DNx, UniProtKB:P15509] comment: Category=organism-sequence. synonym: "hCSF2RA/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P15509-3 is_a: PR:P15509 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:A9P557 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 2 (mouse) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A9P557. This isoform lacks part of the Fibronectin type-III (PS50853) domain." [GenBank:EF114317, GenPept:ABO38428, PMID:17694571, PRO:HJD] comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:17694571, at protein level). Note: PMID:17694571 shows that this isoform may be produced from a transcript where skipping of the splice acceptor of exon 6 and aberrant splicing into the coding sequence of exon 6 occurs. synonym: "mCSF2RA/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "GMRalpha isoform 2 (mouse)" EXACT [] synonym: "GM-CSF receptor alpha-chain isoform 2 (mouse)" EXACT [] synonym: "GM-CSF receptor alpha subunit isoform 2 (mouse)" EXACT [] xref: UniProtKB:A9P557 is_a: PR:Q00941 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000018424 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha, signal peptide removed form def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "CSF2RA/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000001354 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:P15509-6 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h6 (human) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-6." [PRO:DNx, UniProtKB:P15509] comment: Category=organism-sequence. synonym: "hCSF2RA/iso:h6" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P15509-6 is_a: PR:P15509 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P15509-7 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h7 (human) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-7." [PRO:DNx, UniProtKB:P15509] comment: Category=organism-sequence. synonym: "hCSF2RA/iso:h7" EXACT PRO-short-label [PRO:DNx] synonym: "granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform Alu-GMRalpha (human)" EXACT [UniProtKB:P15509] xref: UniProtKB:P15509-7 is_a: PR:P15509 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P15509-4 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h4 (human) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-4." [PRO:DNx, UniProtKB:P15509] comment: Category=organism-sequence. synonym: "hCSF2RA/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P15509-4 is_a: PR:P15509 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P15509-5 name: granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h5 (human) def: "A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-5." [PRO:DNx, UniProtKB:P15509] comment: Category=organism-sequence. synonym: "hCSF2RA/iso:h5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P15509-5 is_a: PR:P15509 ! granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens