[Term] id: PR:Q7Z6A9-2 name: B- and T-lymphocyte attenuator isoform h2 (human) def: "A B- and T-lymphocyte attenuator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z6A9-2." [PRO:DNx, UniProtKB:Q7Z6A9] comment: Category=organism-sequence. synonym: "hBTLA/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q7Z6A9-2 is_a: PR:Q7Z6A9 ! B- and T-lymphocyte attenuator (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q7Z6A9 name: B- and T-lymphocyte attenuator (human) def: "A B- and T-lymphocyte attenuator that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q7Z6A9] comment: Category=organism-gene. synonym: "BTLA" RELATED Gene-based [UniProtKB:Q7Z6A9] synonym: "hBTLA" EXACT PRO-short-label [PRO:DNx] synonym: "CD272 (human)" EXACT [UniProtKB:Q7Z6A9] synonym: "B- and T-lymphocyte-associated protein (human)" EXACT [UniProtKB:Q7Z6A9] xref: UniProtKB:Q7Z6A9 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001284 ! B- and T-lymphocyte attenuator relationship: has_gene_template HGNC:21087 ! BTLA (human) [Term] id: PR:Q7Z6A9-1 name: B- and T-lymphocyte attenuator isoform h1 (human) def: "A B- and T-lymphocyte attenuator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z6A9-1." [PRO:DNx, UniProtKB:Q7Z6A9] comment: Category=organism-sequence. synonym: "hBTLA/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q7Z6A9-1 is_a: PR:Q7Z6A9 ! B- and T-lymphocyte attenuator (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000046521 name: B- and T-lymphocyte attenuator, signal peptide removed phosphorylated 1 (human) def: "A B- and T-lymphocyte attenuator (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 226, 257 and 282 of the amino acid sequence represented by UniProtKB:Q7Z6A9. UniProtKB:Q7Z6A9, 31-289, Tyr-226/Tyr-257/Tyr-282, MOD:00048." [PRO:DNx, Reactome:R-HSA-389925] comment: Category=organism-modification. synonym: "hBTLA/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000014523, Tyr-226/Tyr-257/Tyr-282, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q7Z6A9, 31-289, Tyr-226/Tyr-257/Tyr-282, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-389925 "PR:000046521 located_in GO:0005886" is_a: PR:Q7Z6A9 ! B- and T-lymphocyte attenuator (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000046520 name: B- and T-lymphocyte attenuator, signal peptide removed form (human) def: "A B- and T-lymphocyte attenuator (human) that has had the signal peptide removed. UniProtKB:Q7Z6A9, 31-289." [PRO:DNx, Reactome:R-HSA-197774] comment: Category=organism-modification. synonym: "hBTLA/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000014523" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q7Z6A9, 31-289" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-197774 "PR:000046520 located_in GO:0005886" intersection_of: PR:Q7Z6A9 ! B- and T-lymphocyte attenuator (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000001284 name: B- and T-lymphocyte attenuator def: "A protein that is a translation product of the human BTLA gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. synonym: "BTLA" EXACT PRO-short-label [PRO:DNx] synonym: "CD272" EXACT [] synonym: "B- and T-lymphocyte-associated protein" EXACT [] xref: PIRSF:PIRSF038341 is_a: PR:000000001 ! protein