[Term]
id: PR:P78325
name: disintegrin and metalloproteinase domain-containing protein 8 (human)
def: "A disintegrin and metalloproteinase domain-containing protein 8 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P78325]
comment: Category=organism-gene.
synonym: "MS2" RELATED Gene-based [UniProtKB:P78325]
synonym: "ADAM8" RELATED Gene-based [UniProtKB:P78325]
synonym: "hADAM8" EXACT PRO-short-label [PRO:DNx]
synonym: "ADAM 8 (human)" EXACT [UniProtKB:P78325]
synonym: "CD156a (human)" EXACT [UniProtKB:P78325]
synonym: "cell surface antigen MS2 (human)" EXACT [UniProtKB:P78325]
xref: UniProtKB:P78325
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001280 ! disintegrin and metalloproteinase domain-containing protein 8
relationship: has_gene_template HGNC:215 ! ADAM8 (human)

[Term]
id: PR:000046262
name: disintegrin and metalloproteinase domain-containing protein 8, signal peptide removed form (human)
def: "A disintegrin and metalloproteinase domain-containing protein 8 (human) that has had the signal peptide removed. UniProtKB:P78325, 17-824." [PRO:DNx, Reactome:R-HSA-708331]
comment: Category=organism-modification.
synonym: "PRO_0000029060" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hADAM8/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P78325, 17-824" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-708331 "PR:000046262 located_in GO:0005886"
xref: Reactome:R-HSA-6799563 "PR:000046262 located_in GO:0035579"
xref: Reactome:R-HSA-6800884 "PR:000046262 located_in GO:0070821"
xref: Reactome:R-HSA-6801017 "PR:000046262 located_in GO:0101003"
intersection_of: PR:P78325 ! disintegrin and metalloproteinase domain-containing protein 8 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000001280
name: disintegrin and metalloproteinase domain-containing protein 8
def: "A protein that is a translation product of the human ADAM8 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "MS2" RELATED Gene-based []
synonym: "ADAM8" EXACT PRO-short-label [PRO:DNx]
synonym: "ADAM 8" EXACT []
synonym: "CD156a" EXACT []
synonym: "ADAM 8 endopeptidase" EXACT []
synonym: "cell surface antigen MS2" EXACT []
synonym: "macrophage cysteine-rich glycoprotein" EXACT []
xref: IUPHARobj:1656
is_a: PR:000000001 ! protein

[Term]
id: PR:P78325-3
name: disintegrin and metalloproteinase domain-containing protein 8 isoform h3 (human)
def: "A disintegrin and metalloproteinase domain-containing protein 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78325-3." [PRO:DNx, UniProtKB:P78325]
comment: Category=organism-sequence.
synonym: "hADAM8/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P78325-3
is_a: PR:P78325 ! disintegrin and metalloproteinase domain-containing protein 8 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P78325-2
name: disintegrin and metalloproteinase domain-containing protein 8 isoform h2 (human)
def: "A disintegrin and metalloproteinase domain-containing protein 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78325-2." [PRO:DNx, UniProtKB:P78325]
comment: Category=organism-sequence.
synonym: "hADAM8/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P78325-2
is_a: PR:P78325 ! disintegrin and metalloproteinase domain-containing protein 8 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P78325-1
name: disintegrin and metalloproteinase domain-containing protein 8 isoform h1 (human)
def: "A disintegrin and metalloproteinase domain-containing protein 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78325-1." [PRO:DNx, UniProtKB:P78325]
comment: Category=organism-sequence.
synonym: "hADAM8/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P78325-1
is_a: PR:P78325 ! disintegrin and metalloproteinase domain-containing protein 8 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens