[Term]
id: PR:000001222
name: endothelin receptor type B
def: "An endothelin receptor that is a translation product of the human EDNRB gene or a 1:1 ortholog thereof. The active form binds endothelin 1 (ET-1), ET-2, and ET-3 with equal affinity." [PMID:12037137, PRO:WCB]
comment: Category=gene.
synonym: "ET-B" BROAD [PRO:DNx]
synonym: "ETRB" RELATED Gene-based []
synonym: "EDNRB" EXACT PRO-short-label [PRO:DNx]
synonym: "ET-BR" EXACT []
synonym: "endothelin B receptor" EXACT []
synonym: "endothelin receptor B" EXACT []
synonym: "endothelin receptor non-selective type" EXACT []
xref: IUPHARobj:220
is_a: PR:000001133 ! endothelin receptor

[Term]
id: PR:P24530-2
name: endothelin receptor type B isoform B (human)
def: "An endothelin receptor type B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24530-2." [PRO:DNx, UniProtKB:P24530]
comment: Category=organism-sequence.
synonym: "hEDNRB/iso:B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P24530-2
is_a: PR:P24530 ! endothelin receptor type B (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P24530-3
name: endothelin receptor type B isoform C (human)
def: "An endothelin receptor type B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24530-3." [PRO:DNx, UniProtKB:P24530]
comment: Category=organism-sequence.
synonym: "hEDNRB/iso:C" EXACT PRO-short-label [PRO:DNx]
synonym: "endothelin receptor type B isoform Delta-3 (human)" EXACT [UniProtKB:P24530]
xref: UniProtKB:P24530-3
is_a: PR:P24530 ! endothelin receptor type B (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P24530
name: endothelin receptor type B (human)
def: "An endothelin receptor type B that is encoded in the genome of human." [PRO:WCB, UniProtKB:P24530]
comment: Category=organism-gene.
synonym: "ETRB" RELATED Gene-based [UniProtKB:P24530]
synonym: "EDNRB" RELATED Gene-based [UniProtKB:P24530]
synonym: "hEDNRB" EXACT PRO-short-label [PRO:DNx]
synonym: "ET-B (human)" EXACT [UniProtKB:P24530]
synonym: "ET-BR (human)" EXACT [UniProtKB:P24530]
synonym: "endothelin receptor non-selective type (human)" EXACT [UniProtKB:P24530]
xref: DTO:02100087
xref: UniProtKB:P24530
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001222 ! endothelin receptor type B
relationship: has_gene_template HGNC:3180 ! EDNRB (human)

[Term]
id: PR:000047246
name: endothelin B receptor, signal peptide removed form (human)
def: "An endothelin receptor type B (human) that has had the signal peptide removed. UniProtKB:P24530, 27-442." [PRO:DNx, Reactome:R-HSA-388550]
comment: Category=organism-modification.
synonym: "PRO_0000012729" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hEDNRB/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P24530, 27-442" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-388550 "PR:000047246 located_in GO:0005886"
intersection_of: PR:P24530 ! endothelin receptor type B (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P24530-1
name: endothelin receptor type B isoform A (human)
def: "An endothelin receptor type B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24530-1." [PRO:DNx, UniProtKB:P24530]
comment: Category=organism-sequence.
synonym: "hEDNRB/iso:A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P24530-1
is_a: PR:P24530 ! endothelin receptor type B (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens