[Term]
id: PR:000001208
name: C-X-C chemokine receptor type 4
def: "A chemokine receptor that is a translation product of the human CXCR4 gene or a 1:1 ortholog thereof. The preferred ligand is CXCL12." [PMID:12037138, PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "FB22" EXACT []
synonym: "HM89" EXACT []
synonym: "LCR1" EXACT []
synonym: "CD184" EXACT []
synonym: "CXCR4" EXACT PRO-short-label [PRO:DNx]
synonym: "LESTR" EXACT []
synonym: "NPYRL" EXACT []
synonym: "Sdf1r" RELATED Gene-based []
synonym: "fusin" EXACT []
synonym: "CXC-R4" EXACT []
synonym: "CXCR-4" EXACT []
synonym: "Cmkar4" RELATED Gene-based []
synonym: "PB-CKR" EXACT []
synonym: "SDF-1 receptor" EXACT []
synonym: "chemokine receptor CXCR4" EXACT []
synonym: "pre-B-cell-derived chemokine receptor" EXACT []
synonym: "stromal cell-derived factor 1 receptor" EXACT []
synonym: "leukocyte-derived seven transmembrane domain receptor" EXACT []
xref: IUPHARobj:71
xref: PIRSF:PIRSF501021
is_a: PR:000001128 ! chemokine receptor

[Term]
id: PR:P61073
name: C-X-C chemokine receptor type 4 (human)
def: "A C-X-C chemokine receptor type 4 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P61073]
comment: Category=organism-gene.
synonym: "CXCR4" RELATED Gene-based [UniProtKB:P61073]
synonym: "hCXCR4" EXACT PRO-short-label [PRO:DNx]
synonym: "FB22 (human)" EXACT [UniProtKB:P61073]
synonym: "HM89 (human)" EXACT [UniProtKB:P61073]
synonym: "LCR1 (human)" EXACT [UniProtKB:P61073]
synonym: "CD184 (human)" EXACT [UniProtKB:P61073]
synonym: "LAP-3 (human)" BROAD [UniProtKB:P61073]
synonym: "LESTR (human)" EXACT [UniProtKB:P61073]
synonym: "NPYRL (human)" EXACT [UniProtKB:P61073]
synonym: "fusin (human)" EXACT [UniProtKB:P61073]
synonym: "CXC-R4 (human)" EXACT [UniProtKB:P61073]
synonym: "CXCR-4 (human)" EXACT [UniProtKB:P61073]
synonym: "SDF-1 receptor (human)" EXACT [UniProtKB:P61073]
synonym: "LPS-associated protein 3 (human)" EXACT [UniProtKB:P61073]
synonym: "stromal cell-derived factor 1 receptor (human)" EXACT [UniProtKB:P61073]
synonym: "lipopolysaccharide-associated protein 3 (human)" EXACT [UniProtKB:P61073]
synonym: "leukocyte-derived seven transmembrane domain receptor (human)" EXACT [UniProtKB:P61073]
xref: UniProtKB:P61073
xref: Reactome:R-HSA-2980772 "PR:P61073 located_in GO:0005886"
xref: DTO:02100078
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001208 ! C-X-C chemokine receptor type 4
relationship: has_gene_template HGNC:2561 ! CXCR4 (human)

[Term]
id: PR:P61073-2
name: C-X-C chemokine receptor type 4 isoform h2 (human)
def: "A C-X-C chemokine receptor type 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61073-2." [PRO:DNx, UniProtKB:P61073]
comment: Category=organism-sequence.
synonym: "hCXCR4/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "C-X-C chemokine receptor type 4 isoform CXCR4-LO (human)" EXACT [UniProtKB:P61073]
xref: UniProtKB:P61073-2
is_a: PR:P61073 ! C-X-C chemokine receptor type 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P61073-1
name: C-X-C chemokine receptor type 4 isoform h1 (human)
def: "A C-X-C chemokine receptor type 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61073-1." [PRO:DNx, UniProtKB:P61073]
comment: Category=organism-sequence.
synonym: "hCXCR4/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P61073-1
is_a: PR:P61073 ! C-X-C chemokine receptor type 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens