[Term]
id: PR:000001160
name: Toll-like receptor 9
def: "A Toll-like receptor that is a translation product of the human TLR9 gene or a 1:1 ortholog thereof. Non-methylated CpG motifs, present in viral and bacterial DNA, are one of many pathogen-associated molecular patterns (PAMP) recognized by the mammalian innate immune system. Recognition of this PAMP occurs through a specific interaction with Toll-like receptor 9 and this interaction can induce cytokine responses that influence both innate and adaptive immune responses." [PMID:11022119]
comment: Category=gene.
synonym: "TLR9" EXACT PRO-short-label [PRO:DNx]
synonym: "CD289" EXACT []
synonym: "UNQ5798/PRO19605" RELATED Gene-based []
xref: IUPHARobj:1759
xref: PANTHER:PTHR24365:SF58
is_a: PR:000001096 ! Toll-like receptor

[Term]
id: PR:Q9EQU3
name: Toll-like receptor 9 (mouse)
def: "A Toll-like receptor 9 that is encoded in the genome of mouse." [PRO:DAN, UniProtKB:Q9EQU3]
comment: Category=organism-gene.
synonym: "Tlr9" RELATED Gene-based [UniProtKB:Q9EQU3]
synonym: "mTLR9" EXACT PRO-short-label [PRO:DNx]
synonym: "CD289 (mouse)" EXACT [UniProtKB:Q9EQU3]
xref: UniProtKB:Q9EQU3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001160 ! Toll-like receptor 9
relationship: has_gene_template MGI:1932389 ! Tlr9 (mouse)