[Term]
id: PR:000036602
name: interleukin-17A, signal peptide removed form (human)
def: "An interleukin-17A, signal peptide removed form in human. UniProtKB:Q16552, 24-155." [PMID:15055556, PMID:15340161, PMID:7499828, PRO:CNA]
comment: Category=organism-modification.
synonym: "PRO_0000015423" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hIL17A/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16552, 24-155" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-447093 "PR:000036602 located_in GO:0005576"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000018349 ! interleukin-17A, signal peptide removed form

[Term]
id: PR:Q16552
name: interleukin-17A (human)
def: "An interleukin-17A that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q16552]
comment: Category=organism-gene.
synonym: "IL17" RELATED Gene-based [UniProtKB:Q16552]
synonym: "CTLA8" RELATED Gene-based [UniProtKB:Q16552]
synonym: "IL17A" RELATED Gene-based [UniProtKB:Q16552]
synonym: "hIL17A" EXACT PRO-short-label [PRO:DNx]
synonym: "IL-17 (human)" EXACT [UniProtKB:Q16552]
synonym: "CTLA-8 (human)" EXACT [UniProtKB:Q16552]
synonym: "IL-17A (human)" EXACT [UniProtKB:Q16552]
synonym: "cytotoxic T-lymphocyte-associated antigen 8 (human)" EXACT [UniProtKB:Q16552]
xref: UniProtKB:Q16552
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001138 ! interleukin-17A
relationship: has_gene_template HGNC:5981 ! IL17A (human)

[Term]
id: PR:000001138
name: interleukin-17A
def: "An interleukin-17 that is a translation product of the human IL17A gene or a 1:1 ortholog thereof. The active product is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases." [PRO:CNA, Wikipedia:IL17A]
comment: Category=gene.
synonym: "IL17" RELATED Gene-based []
synonym: "CTLA8" RELATED Gene-based []
synonym: "IL-17" RELATED []
synonym: "IL17A" EXACT PRO-short-label [PRO:DNx]
synonym: "CTLA-8" EXACT []
synonym: "IL-17A" EXACT []
synonym: "cytotoxic T-lymphocyte-associated antigen 8" EXACT []
xref: PIRSF:PIRSF501045
is_a: PR:000001092 ! interleukin-17