[Term]
id: PR:Q9HBA0
name: transient receptor potential cation channel subfamily V member 4 (human)
def: "A transient receptor potential cation channel TRPV4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9HBA0]
comment: Category=organism-gene.
synonym: "VRL2" RELATED Gene-based [UniProtKB:Q9HBA0]
synonym: "TRPV4" RELATED Gene-based [UniProtKB:Q9HBA0]
synonym: "VROAC" RELATED Gene-based [UniProtKB:Q9HBA0]
synonym: "hTRPV4" EXACT PRO-short-label [PRO:DNx]
synonym: "TRP12 (human)" EXACT [UniProtKB:Q9HBA0]
synonym: "TrpV4 (human)" EXACT [UniProtKB:Q9HBA0]
synonym: "VRL-2 (human)" EXACT [UniProtKB:Q9HBA0]
synonym: "OTRPC4 (human)" EXACT [UniProtKB:Q9HBA0]
synonym: "VR-OAC (human)" EXACT [UniProtKB:Q9HBA0]
synonym: "Osm-9-like TRP channel 4 (human)" EXACT [UniProtKB:Q9HBA0]
synonym: "vanilloid receptor-like channel 2 (human)" EXACT [UniProtKB:Q9HBA0]
synonym: "vanilloid receptor-like protein 2 (human)" EXACT [UniProtKB:Q9HBA0]
synonym: "transient receptor potential protein 12 (human)" EXACT [UniProtKB:Q9HBA0]
synonym: "vanilloid receptor-related osmotically-activated channel (human)" EXACT [UniProtKB:Q9HBA0]
xref: UniProtKB:Q9HBA0
xref: Reactome:R-HSA-1297261 "PR:Q9HBA0 located_in GO:0005886"
xref: DTO:01100336
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001068 ! transient receptor potential cation channel TRPV4
relationship: has_gene_template HGNC:18083 ! TRPV4 (human)

[Term]
id: PR:Q9HBA0-6
name: transient receptor potential cation channel subfamily V member 4 isoform E (human)
def: "A transient receptor potential cation channel TRPV4 isoform E that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9HBA0]
comment: Category=organism-sequence.
synonym: "hTRPV4/iso:6" RELATED [PRO:DNx]
synonym: "hTRPV4/iso:E" EXACT PRO-short-label [PRO:DNx]
synonym: "transient receptor potential cation channel subfamily V member 4 isoform 6 (human)" EXACT [UniProtKB:Q9HBA0]
xref: UniProtKB:Q9HBA0-6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001073 ! transient receptor potential cation channel TRPV4 isoform E

[Term]
id: PR:Q9HBA0-3
name: transient receptor potential cation channel subfamily V member 4 isoform h3 (human)
def: "A transient receptor potential cation channel subfamily V member 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9HBA0-3." [PRO:DNx, UniProtKB:Q9HBA0]
comment: Category=organism-sequence.
synonym: "hTRPV4/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "transient receptor potential cation channel subfamily V member 4 isoform TRPV-SV (human)" EXACT [UniProtKB:Q9HBA0]
xref: UniProtKB:Q9HBA0-3
is_a: PR:Q9HBA0 ! transient receptor potential cation channel subfamily V member 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9HBA0-2
name: transient receptor potential cation channel subfamily V member 4 isoform B (human)
def: "A transient receptor potential cation channel TRPV4 isoform B that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9HBA0]
comment: Category=organism-sequence.
synonym: "hTRPV4/iso:2" RELATED [PRO:DNx]
synonym: "hTRPV4/iso:B" EXACT PRO-short-label [PRO:DNx]
synonym: "transient receptor potential cation channel subfamily V member 4 isoform 2 (human)" EXACT [UniProtKB:Q9HBA0]
synonym: "transient receptor potential cation channel subfamily V member 4 isoform OTRPC4beta (human)" EXACT [UniProtKB:Q9HBA0]
xref: UniProtKB:Q9HBA0-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001070 ! transient receptor potential cation channel TRPV4 isoform B

[Term]
id: PR:Q9HBA0-1
name: transient receptor potential cation channel subfamily V member 4 isoform A (human)
def: "A transient receptor potential cation channel TRPV4 isoform A that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hTRPV4/iso:A" EXACT PRO-short-label [PRO:DNx]
synonym: "TRPV4 isoform 1 (human)" EXACT [PRO:DNx]
synonym: "transient receptor potential cation channel subfamily V member 4 isoform 1 (human)" EXACT [UniProtKB:Q9HBA0]
xref: UniProtKB:Q9HBA0-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001069 ! transient receptor potential cation channel TRPV4 isoform A

[Term]
id: PR:000001068
name: transient receptor potential cation channel TRPV4
def: "A transient receptor potential cation channel TRPV that is a translation product of the human TRPV4 gene or a 1:1 ortholog thereof. The functional subunits are ion-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification." [PRO:CNA, UniProtKB:Q9HBA0]
comment: Category=gene.
synonym: "VRL2" RELATED Gene-based []
synonym: "TRP12" EXACT []
synonym: "TRPV4" EXACT PRO-short-label [PRO:DNx]
synonym: "TrpV4" EXACT []
synonym: "VRL-2" EXACT []
synonym: "VROAC" RELATED Gene-based []
synonym: "OTRPC4" EXACT []
synonym: "VR-OAC" EXACT []
synonym: "Osm-9-like TRP channel 4" EXACT []
synonym: "vanilloid receptor-like channel 2" EXACT []
synonym: "vanilloid receptor-like protein 2" EXACT []
synonym: "transient receptor potential protein 12" EXACT []
synonym: "vanilloid receptor-related osmotically-activated channel" EXACT []
xref: IUPHARobj:510
is_a: PR:000000681 ! transient receptor potential cation channel TRPV

[Term]
id: PR:Q9HBA0-5
name: transient receptor potential cation channel subfamily V member 4 isoform D (human)
def: "A transient receptor potential cation channel TRPV4 isoform D that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9HBA0]
comment: Category=organism-sequence.
synonym: "hTRPV4/iso:5" RELATED [PRO:DNx]
synonym: "hTRPV4/iso:D" EXACT PRO-short-label [PRO:DNx]
synonym: "transient receptor potential cation channel subfamily V member 4 isoform 5 (human)" EXACT [UniProtKB:Q9HBA0]
xref: UniProtKB:Q9HBA0-5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001072 ! transient receptor potential cation channel TRPV4 isoform D

[Term]
id: PR:Q9HBA0-4
name: transient receptor potential cation channel subfamily V member 4 isoform C (human)
def: "A transient receptor potential cation channel TRPV4 isoform C that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9HBA0]
comment: Category=organism-sequence.
synonym: "hTRPV4/iso:4" RELATED [PRO:DNx]
synonym: "hTRPV4/iso:C" EXACT PRO-short-label [PRO:DNx]
synonym: "transient receptor potential cation channel subfamily V member 4 isoform 4 (human)" EXACT [UniProtKB:Q9HBA0]
xref: UniProtKB:Q9HBA0-4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001071 ! transient receptor potential cation channel TRPV4 isoform C