[Term]
id: PR:Q9EPK8-1
name: transient receptor potential cation channel subfamily V member 4 isoform A (mouse)
def: "A transient receptor potential cation channel TRPV4 isoform A that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mTRPV4/iso:A" EXACT PRO-short-label [PRO:DNx]
synonym: "Trpv4 isoform 1 (mouse)" EXACT [PRO:DNx]
synonym: "transient receptor potential cation channel subfamily V member 4 isoform 1 (mouse)" EXACT [PRO:DNx]
xref: UniProtKB:Q9EPK8-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001069 ! transient receptor potential cation channel TRPV4 isoform A

[Term]
id: PR:000001068
name: transient receptor potential cation channel TRPV4
def: "A transient receptor potential cation channel TRPV that is a translation product of the human TRPV4 gene or a 1:1 ortholog thereof. The functional subunits are ion-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification." [PRO:CNA, UniProtKB:Q9HBA0]
comment: Category=gene.
synonym: "VRL2" RELATED Gene-based []
synonym: "TRP12" EXACT []
synonym: "TRPV4" EXACT PRO-short-label [PRO:DNx]
synonym: "TrpV4" EXACT []
synonym: "VRL-2" EXACT []
synonym: "VROAC" RELATED Gene-based []
synonym: "OTRPC4" EXACT []
synonym: "VR-OAC" EXACT []
synonym: "Osm-9-like TRP channel 4" EXACT []
synonym: "vanilloid receptor-like channel 2" EXACT []
synonym: "vanilloid receptor-like protein 2" EXACT []
synonym: "transient receptor potential protein 12" EXACT []
synonym: "vanilloid receptor-related osmotically-activated channel" EXACT []
xref: IUPHARobj:510
is_a: PR:000000681 ! transient receptor potential cation channel TRPV

[Term]
id: PR:000046053
name: transient receptor potential cation channel subfamily V member 4 phosphorylated 1 (mouse)
def: "A transient receptor potential cation channel subfamily V member 4 (mouse) that has been phosphorylated at Tyr-253. UniProtKB:Q9EPK8, Tyr-253, MOD:00048." [PMID:12538589, iPTMnet:Q9EPK8]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:12538589). Status=unreviewed.
synonym: "mTRPV4/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9EPK8, Tyr-253, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9EPK8 ! transient receptor potential cation channel subfamily V member 4 (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9EPK8
name: transient receptor potential cation channel subfamily V member 4 (mouse)
def: "A transient receptor potential cation channel TRPV4 that is encoded in the genome of mouse." [OMA:Q9EPK8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Vrl2" RELATED Gene-based [UniProtKB:Q9EPK8]
synonym: "Trp12" RELATED Gene-based [UniProtKB:Q9EPK8]
synonym: "Trpv4" RELATED Gene-based [UniProtKB:Q9EPK8]
synonym: "Vroac" RELATED Gene-based [UniProtKB:Q9EPK8]
synonym: "mTRPV4" EXACT PRO-short-label [PRO:DNx]
synonym: "TRP12 (mouse)" EXACT [UniProtKB:Q9EPK8]
synonym: "TrpV4 (mouse)" EXACT [UniProtKB:Q9EPK8]
synonym: "OTRPC4 (mouse)" EXACT [UniProtKB:Q9EPK8]
synonym: "VR-OAC (mouse)" EXACT [UniProtKB:Q9EPK8]
synonym: "Osm-9-like TRP channel 4 (mouse)" EXACT [UniProtKB:Q9EPK8]
synonym: "vanilloid receptor-like channel 2 (mouse)" EXACT [UniProtKB:Q9EPK8]
synonym: "vanilloid receptor-like protein 2 (mouse)" EXACT [UniProtKB:Q9EPK8]
synonym: "transient receptor potential protein 12 (mouse)" EXACT [UniProtKB:Q9EPK8]
synonym: "vanilloid receptor-related osmotically-activated channel (mouse)" EXACT [UniProtKB:Q9EPK8]
xref: UniProtKB:Q9EPK8
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001068 ! transient receptor potential cation channel TRPV4
relationship: has_gene_template MGI:1926945 ! Trpv4 (mouse)