[Term]
id: PR:000001012
name: integrin alpha-M
def: "An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1." [UniProtKB:P11215]
comment: Category=gene. Requested by=CL.
synonym: "CR3A" RELATED Gene-based []
synonym: "CD11B" RELATED Gene-based []
synonym: "CD11b" EXACT []
synonym: "ITGAM" EXACT PRO-short-label [PRO:DNx]
synonym: "CR-3 alpha chain" EXACT []
synonym: "neutrophil adherence receptor" EXACT []
synonym: "leukocyte adhesion receptor MO1" EXACT []
synonym: "CD11 antigen-like family member B" EXACT []
synonym: "cell surface glycoprotein MAC-1 subunit alpha" EXACT []
xref: IUPHARobj:2452
is_a: PR:000001005 ! integrin alpha with A domain