[Term]
id: PR:P35832
name: tyrosine-protein phosphatase 99A (fruit fly)
def: "A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of fruit fly." [OMA:P35832, PRO:DNx]
comment: Category=organism-gene.
synonym: "CG2005" RELATED Gene-based [UniProtKB:P35832]
synonym: "Ptp99A" RELATED Gene-based [UniProtKB:P35832]
synonym: "fly-PTPRC" EXACT PRO-short-label [PRO:DNx]
synonym: "DPTP99A (fruit fly)" EXACT [UniProtKB:P35832]
synonym: "receptor-linked protein-tyrosine phosphatase 99A (fruit fly)" EXACT [UniProtKB:P35832]
xref: UniProtKB:P35832
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000001006 ! receptor-type tyrosine-protein phosphatase C
relationship: has_gene_template FlyBase:FBgn0004369 ! Ptp99A (fruit fly)

[Term]
id: PR:000001006
name: receptor-type tyrosine-protein phosphatase C
def: "A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule." [PMID:1351092, PRO:CNA]
comment: Category=gene. Requested by=CL.
synonym: "CD45" RELATED Gene-based []
synonym: "L-CA" EXACT []
synonym: "T200" BROAD [PRO:DNx]
synonym: "ly-5" EXACT []
synonym: "PTPRC" EXACT PRO-short-label [PRO:DNx]
synonym: "lymphocyte antigen 5" EXACT []
synonym: "leukocyte common antigen" EXACT []
xref: IUPHARobj:1852
xref: PIRSF:PIRSF002004
is_a: PR:000000001 ! protein

[Term]
id: PR:P35832-4
name: tyrosine-protein phosphatase 99A isoform D (fruit fly)
def: "A tyrosine-protein phosphatase 99A (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35832-4." [PRO:DNx, UniProtKB:P35832]
comment: Category=organism-sequence.
synonym: "fly-PTPRC/iso:D" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35832-4
is_a: PR:P35832 ! tyrosine-protein phosphatase 99A (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:P35832-3
name: tyrosine-protein phosphatase 99A isoform C (fruit fly)
def: "A tyrosine-protein phosphatase 99A (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35832-3." [PRO:DNx, UniProtKB:P35832]
comment: Category=organism-sequence.
synonym: "fly-PTPRC/iso:C" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35832-3
is_a: PR:P35832 ! tyrosine-protein phosphatase 99A (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:P35832-2
name: tyrosine-protein phosphatase 99A isoform A (fruit fly)
def: "A tyrosine-protein phosphatase 99A (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35832-2." [PRO:DNx, UniProtKB:P35832]
comment: Category=organism-sequence.
synonym: "fly-PTPRC/iso:A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35832-2
is_a: PR:P35832 ! tyrosine-protein phosphatase 99A (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:P35832-1
name: tyrosine-protein phosphatase 99A isoform B (fruit fly)
def: "A tyrosine-protein phosphatase 99A (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35832-1." [PRO:DNx, UniProtKB:P35832]
comment: Category=organism-sequence.
synonym: "fly-PTPRC/iso:B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35832-1
is_a: PR:P35832 ! tyrosine-protein phosphatase 99A (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster