[Term]
id: PR:P06800
name: receptor-type tyrosine-protein phosphatase C (mouse)
def: "A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of mouse." [OMA:P06800, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ly-5" RELATED Gene-based [UniProtKB:P06800]
synonym: "Ptprc" RELATED Gene-based [UniProtKB:P06800]
synonym: "mPTPRC" EXACT PRO-short-label [PRO:DNx]
synonym: "CD45 (mouse)" EXACT [UniProtKB:P06800]
synonym: "L-CA (mouse)" EXACT [UniProtKB:P06800]
synonym: "T200 (mouse)" EXACT [UniProtKB:P06800]
synonym: "lymphocyte antigen 5 (mouse)" EXACT [UniProtKB:P06800]
synonym: "leukocyte common antigen (mouse)" EXACT [UniProtKB:P06800]
xref: UniProtKB:P06800
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001006 ! receptor-type tyrosine-protein phosphatase C
relationship: has_gene_template MGI:97810 ! Ptprc (mouse)

[Term]
id: PR:P06800-6
name: receptor-type tyrosine-protein phosphatase C isoform m3 (mouse)
def: "A receptor-type tyrosine-protein phosphatase C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06800-6." [PRO:DNx, UniProtKB:P06800]
comment: Category=organism-sequence.
synonym: "mPTPRC/iso:m3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06800-6
is_a: PR:P06800 ! receptor-type tyrosine-protein phosphatase C (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P06800-4
name: receptor-type tyrosine-protein phosphatase C isoform m1 (mouse)
def: "A receptor-type tyrosine-protein phosphatase C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06800-4." [PRO:DNx, UniProtKB:P06800]
comment: Category=organism-sequence.
synonym: "mPTPRC/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06800-4
is_a: PR:P06800 ! receptor-type tyrosine-protein phosphatase C (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P06800-5
name: receptor-type tyrosine-protein phosphatase C isoform m2 (mouse)
def: "A receptor-type tyrosine-protein phosphatase C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06800-5." [PRO:DNx, UniProtKB:P06800]
comment: Category=organism-sequence.
synonym: "mPTPRC/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06800-5
is_a: PR:P06800 ! receptor-type tyrosine-protein phosphatase C (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000001006
name: receptor-type tyrosine-protein phosphatase C
def: "A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule." [PMID:1351092, PRO:CNA]
comment: Category=gene. Requested by=CL.
synonym: "CD45" RELATED Gene-based []
synonym: "L-CA" EXACT []
synonym: "T200" BROAD [PRO:DNx]
synonym: "ly-5" EXACT []
synonym: "PTPRC" EXACT PRO-short-label [PRO:DNx]
synonym: "lymphocyte antigen 5" EXACT []
synonym: "leukocyte common antigen" EXACT []
xref: IUPHARobj:1852
xref: PIRSF:PIRSF002004
is_a: PR:000000001 ! protein

[Term]
id: PR:000050324
name: receptor-type tyrosine-protein phosphatase C isoform x1 (mouse)
def: "A receptor-type tyrosine-protein phosphatase C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06800-1. UniProtKB:P06800-4, 3-1293." [PRO:DNx, UniProtKB:P06800]
comment: Category=organism-sequence. Note: Removed from the source database. Formerly known as isoform 1. The isoform represented by UniProtKB:P06800-1 is the same as UniProtKB:P06800-4 except with an alternative start at position 3 relative to the latter. Since the actual start codon is uncertain, we retain this class pending confirmation.
synonym: "mPtprc/iso:x1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06800-4, 3-1293" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "receptor-type tyrosine-protein phosphatase C isoform B220 (mouse)" EXACT [UniProtKB:P06800]
is_a: PR:P06800 ! receptor-type tyrosine-protein phosphatase C (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000050325
name: receptor-type tyrosine-protein phosphatase C isoform 2 (mouse)
def: "A receptor-type tyrosine-protein phosphatase C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06800-2. UniProtKB:P06800-5, 3-1250." [PRO:DAN, UniProtKB:P06800]
comment: Category=organism-sequence. Note: The isoform represented by UniProtKB:P06800-2 (removed from source database) is the same as UniProtKB:P06800-5 except with an alternative start at position 3 relative to the latter. Since the actual start codon is uncertain, we retain this class pending confirmation.
synonym: "mPtprc/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06800-5, 3-1250" EXACT PRO-proteoform-std [PRO:DAN]
is_a: PR:P06800 ! receptor-type tyrosine-protein phosphatase C (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus