[Term]
id: PR:P04157
name: receptor-type tyrosine-protein phosphatase C (rat)
def: "A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of rat." [OMA:P04157, PANTHER:PTHR19134:SF42, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ptprc" RELATED Gene-based [UniProtKB:P04157]
synonym: "rPTPRC" EXACT PRO-short-label [PRO:DNx]
synonym: "CD45 (rat)" EXACT [UniProtKB:P04157]
synonym: "L-CA (rat)" EXACT [UniProtKB:P04157]
synonym: "T200 (rat)" EXACT [UniProtKB:P04157]
synonym: "leukocyte common antigen (rat)" EXACT [UniProtKB:P04157]
xref: UniProtKB:P04157
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000001006 ! receptor-type tyrosine-protein phosphatase C
relationship: has_gene_template RGD:3451 ! Ptprc (rat)

[Term]
id: PR:000001006
name: receptor-type tyrosine-protein phosphatase C
def: "A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule." [PMID:1351092, PRO:CNA]
comment: Category=gene. Requested by=CL.
synonym: "CD45" RELATED Gene-based []
synonym: "L-CA" EXACT []
synonym: "T200" BROAD [PRO:DNx]
synonym: "ly-5" EXACT []
synonym: "PTPRC" EXACT PRO-short-label [PRO:DNx]
synonym: "lymphocyte antigen 5" EXACT []
synonym: "leukocyte common antigen" EXACT []
xref: IUPHARobj:1852
xref: PIRSF:PIRSF002004
is_a: PR:000000001 ! protein

[Term]
id: PR:P04157-5
name: receptor-type tyrosine-protein phosphatase C isoform r5 (rat)
def: "A receptor-type tyrosine-protein phosphatase C (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04157-5." [PRO:DNx, UniProtKB:P04157]
comment: Category=organism-sequence.
synonym: "rPTPRC/iso:r5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P04157-5
is_a: PR:P04157 ! receptor-type tyrosine-protein phosphatase C (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P04157-4
name: receptor-type tyrosine-protein phosphatase C isoform r4 (rat)
def: "A receptor-type tyrosine-protein phosphatase C (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04157-4." [PRO:DNx, UniProtKB:P04157]
comment: Category=organism-sequence.
synonym: "rPTPRC/iso:r4" EXACT PRO-short-label [PRO:DNx]
synonym: "receptor-type tyrosine-protein phosphatase C isoform L-CA variant 3 (rat)" EXACT [UniProtKB:P04157]
xref: UniProtKB:P04157-4
is_a: PR:P04157 ! receptor-type tyrosine-protein phosphatase C (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P04157-1
name: receptor-type tyrosine-protein phosphatase C isoform r1 (rat)
def: "A receptor-type tyrosine-protein phosphatase C (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04157-1." [PRO:DNx, UniProtKB:P04157]
comment: Category=organism-sequence.
synonym: "rPTPRC/iso:r1" EXACT PRO-short-label [PRO:DNx]
synonym: "receptor-type tyrosine-protein phosphatase C isoform L-CA variant 4 (rat)" EXACT [UniProtKB:P04157]
xref: UniProtKB:P04157-1
is_a: PR:P04157 ! receptor-type tyrosine-protein phosphatase C (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P04157-3
name: receptor-type tyrosine-protein phosphatase C isoform r3 (rat)
def: "A receptor-type tyrosine-protein phosphatase C (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04157-3." [PRO:DNx, UniProtKB:P04157]
comment: Category=organism-sequence.
synonym: "rPTPRC/iso:r3" EXACT PRO-short-label [PRO:DNx]
synonym: "receptor-type tyrosine-protein phosphatase C isoform L-CA variant 2 (rat)" EXACT [UniProtKB:P04157]
xref: UniProtKB:P04157-3
is_a: PR:P04157 ! receptor-type tyrosine-protein phosphatase C (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P04157-2
name: receptor-type tyrosine-protein phosphatase C isoform r2 (rat)
def: "A receptor-type tyrosine-protein phosphatase C (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04157-2." [PRO:DNx, UniProtKB:P04157]
comment: Category=organism-sequence.
synonym: "rPTPRC/iso:r2" EXACT PRO-short-label [PRO:DNx]
synonym: "receptor-type tyrosine-protein phosphatase C isoform L-CA variant 1 (rat)" EXACT [UniProtKB:P04157]
xref: UniProtKB:P04157-2
is_a: PR:P04157 ! receptor-type tyrosine-protein phosphatase C (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus