[Term] id: PR:P35832 name: tyrosine-protein phosphatase 99A (fruit fly) def: "A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of fruit fly." [OMA:P35832, PRO:DNx] comment: Category=organism-gene. synonym: "CG2005" RELATED Gene-based [UniProtKB:P35832] synonym: "Ptp99A" RELATED Gene-based [UniProtKB:P35832] synonym: "fly-PTPRC" EXACT PRO-short-label [PRO:DNx] synonym: "DPTP99A (fruit fly)" EXACT [UniProtKB:P35832] synonym: "receptor-linked protein-tyrosine phosphatase 99A (fruit fly)" EXACT [UniProtKB:P35832] xref: UniProtKB:P35832 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000001006 ! receptor-type tyrosine-protein phosphatase C relationship: has_gene_template FlyBase:FBgn0004369 ! Ptp99A (fruit fly) [Term] id: PR:P04157-5 name: receptor-type tyrosine-protein phosphatase C isoform r5 (rat) def: "A receptor-type tyrosine-protein phosphatase C (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04157-5." [PRO:DNx, UniProtKB:P04157] comment: Category=organism-sequence. synonym: "rPTPRC/iso:r5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P04157-5 is_a: PR:P04157 ! receptor-type tyrosine-protein phosphatase C (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:000050216 name: receptor-type tyrosine-protein phosphatase C isoform CD45R def: "A receptor-type tyrosine-protein phosphatase C that is a translation product of a transcript that minimally includes the region encoded by the variable exon 4(A)." [GOC:add, PRO:ADD, PRO:DAN] comment: Category=seqgroup. Requested by=CL. synonym: "CD45R" EXACT [] synonym: "PTPRC/iso:CD45R" EXACT PRO-short-label [PRO:DNx] is_a: PR:000001006 ! receptor-type tyrosine-protein phosphatase C [Term] id: PR:000018306 name: receptor-type tyrosine-protein phosphatase C, signal peptide removed form def: "A receptor-type tyrosine-protein phosphatase C that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "PTPRC/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000001006 ! receptor-type tyrosine-protein phosphatase C intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000025809 name: receptor-type tyrosine-protein phosphatase C isoform CD45RC, signal peptide removed form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RC that has had the signal peptide removed." [PRO:DAN] comment: Category=modification. synonym: "PTPRC/iso:CD45RC/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000025801 ! receptor-type tyrosine-protein phosphatase C isoform CD45RC intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000025808 name: receptor-type tyrosine-protein phosphatase C isoform CD45RO, signal peptide removed form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RO that has had the signal peptide removed." [PRO:DAN] comment: Category=modification. synonym: "PTPRC/iso:CD45RO/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000001017 ! receptor-type tyrosine-protein phosphatase C isoform CD45RO intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:P04157-4 name: receptor-type tyrosine-protein phosphatase C isoform r4 (rat) def: "A receptor-type tyrosine-protein phosphatase C (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04157-4." [PRO:DNx, UniProtKB:P04157] comment: Category=organism-sequence. synonym: "rPTPRC/iso:r4" EXACT PRO-short-label [PRO:DNx] synonym: "receptor-type tyrosine-protein phosphatase C isoform L-CA variant 3 (rat)" EXACT [UniProtKB:P04157] xref: UniProtKB:P04157-4 is_a: PR:P04157 ! receptor-type tyrosine-protein phosphatase C (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:000025801 name: receptor-type tyrosine-protein phosphatase C isoform CD45RC def: "A receptor-type tyrosine-protein phosphatase C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB: or a 1:1 ortholog thereof." [PMID:1351092, PRO:DAN] comment: Category=sequence. Note: This isoform includes the region encoded by the variable exon 6(C), and lacks the region encoded by exons 4(A) and 5(B). synonym: "CD45RC" EXACT [] synonym: "PTPRC/iso:CD45RC" EXACT PRO-short-label [PRO:DNx] is_a: PR:000001006 ! receptor-type tyrosine-protein phosphatase C [Term] id: PR:000025803 name: receptor-type tyrosine-protein phosphatase C isoform CD45RAC def: "A receptor-type tyrosine-protein phosphatase C isoform CD45R that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-6 or a 1:1 ortholog thereof." [PMID:1351092, PRO:DAN] comment: Category=sequence. Note: This isoform includes the region encoded by the variable exons 4(A) and 6(C), and lacks the region encoded by exon 5(B). synonym: "CD45RAC" EXACT [] synonym: "PTPRC/iso:CD45RAC" EXACT PRO-short-label [PRO:DNx] is_a: PR:000050216 ! receptor-type tyrosine-protein phosphatase C isoform CD45R [Term] id: PR:000025802 name: receptor-type tyrosine-protein phosphatase C isoform CD45RAB def: "A receptor-type tyrosine-protein phosphatase C isoform CD45R that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-5 or a 1:1 ortholog thereof." [PMID:1351092, PRO:DAN] comment: Category=sequence. Note: This isoform includes the region encoded by the variable exons 4(A) and 5(B), and lacks the region encoded by exon 6(C). synonym: "CD45RAB" EXACT [] synonym: "PTPRC/iso:CD45RAB" EXACT PRO-short-label [PRO:DNx] is_a: PR:000050216 ! receptor-type tyrosine-protein phosphatase C isoform CD45R [Term] id: PR:000025805 name: receptor-type tyrosine-protein phosphatase C isoform CD45RABC, signal peptide removed form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RABC that has had the signal peptide removed." [PRO:DAN] comment: Category=modification. synonym: "PTPRC/iso:CD45RABC/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000001014 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000025804 name: receptor-type tyrosine-protein phosphatase C isoform CD45RBC def: "A receptor-type tyrosine-protein phosphatase C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-7 or a 1:1 ortholog thereof." [PMID:1351092, PRO:DAN] comment: Category=sequence. Requested by=CL. Note: This isoform includes the region encoded by the variable exons 5(B) and 6(C), and lacks the region encoded by exon 4(A). synonym: "CD45RBC" EXACT [] synonym: "PTPRC/iso:CD45RBC" EXACT PRO-short-label [PRO:DNx] is_a: PR:000001006 ! receptor-type tyrosine-protein phosphatase C [Term] id: PR:000025807 name: receptor-type tyrosine-protein phosphatase C isoform CD45RB, signal peptide removed form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RB that has had the signal peptide removed." [PMID:1351092, PRO:CNA] comment: Category=modification. synonym: "PTPRC/iso:CD45RB/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000001016 ! receptor-type tyrosine-protein phosphatase C isoform CD45RB intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000025806 name: receptor-type tyrosine-protein phosphatase C isoform CD45RA, signal peptide removed form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RA that has had the signal peptide removed." [PMID:1351092, PRO:CNA] comment: Category=modification. synonym: "PTPRC/iso:CD45RA/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:P08575 name: receptor-type tyrosine-protein phosphatase C (human) def: "A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of human." [PRO:CNA, UniProtKB:P08575] comment: Category=organism-gene. synonym: "CD45" RELATED Gene-based [UniProtKB:P08575] synonym: "PTPRC" RELATED Gene-based [UniProtKB:P08575] synonym: "hPTPRC" EXACT PRO-short-label [PRO:DNx] synonym: "L-CA (human)" EXACT [UniProtKB:P08575] synonym: "T200 (human)" EXACT [UniProtKB:P08575] synonym: "leukocyte common antigen (human)" EXACT [UniProtKB:P08575] xref: UniProtKB:P08575 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001006 ! receptor-type tyrosine-protein phosphatase C relationship: has_gene_template HGNC:9666 ! PTPRC (human) [Term] id: PR:000025820 name: receptor-type tyrosine-protein phosphatase C isoform CD45RBC, signal peptide removed glycosylated form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RBC, signal peptide removed form that includes at least one glycosylated residue." [PRO:DAN] comment: Category=modification. synonym: "PTPRC/iso:CD45RBC/SigPep-/GlycoRes+" EXACT PRO-short-label [PRO:DNx] intersection_of: has_part MOD:00693 ! glycosylated residue intersection_of: PR:000025812 ! receptor-type tyrosine-protein phosphatase C isoform CD45RBC, signal peptide removed form [Term] id: PR:P35832-1 name: tyrosine-protein phosphatase 99A isoform B (fruit fly) def: "A tyrosine-protein phosphatase 99A (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35832-1." [PRO:DNx, UniProtKB:P35832] comment: Category=organism-sequence. synonym: "fly-PTPRC/iso:B" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P35832-1 is_a: PR:P35832 ! tyrosine-protein phosphatase 99A (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P04157-1 name: receptor-type tyrosine-protein phosphatase C isoform r1 (rat) def: "A receptor-type tyrosine-protein phosphatase C (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04157-1." [PRO:DNx, UniProtKB:P04157] comment: Category=organism-sequence. synonym: "rPTPRC/iso:r1" EXACT PRO-short-label [PRO:DNx] synonym: "receptor-type tyrosine-protein phosphatase C isoform L-CA variant 4 (rat)" EXACT [UniProtKB:P04157] xref: UniProtKB:P04157-1 is_a: PR:P04157 ! receptor-type tyrosine-protein phosphatase C (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:P35832-2 name: tyrosine-protein phosphatase 99A isoform A (fruit fly) def: "A tyrosine-protein phosphatase 99A (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35832-2." [PRO:DNx, UniProtKB:P35832] comment: Category=organism-sequence. synonym: "fly-PTPRC/iso:A" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P35832-2 is_a: PR:P35832 ! tyrosine-protein phosphatase 99A (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P04157-3 name: receptor-type tyrosine-protein phosphatase C isoform r3 (rat) def: "A receptor-type tyrosine-protein phosphatase C (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04157-3." [PRO:DNx, UniProtKB:P04157] comment: Category=organism-sequence. synonym: "rPTPRC/iso:r3" EXACT PRO-short-label [PRO:DNx] synonym: "receptor-type tyrosine-protein phosphatase C isoform L-CA variant 2 (rat)" EXACT [UniProtKB:P04157] xref: UniProtKB:P04157-3 is_a: PR:P04157 ! receptor-type tyrosine-protein phosphatase C (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:000001006 name: receptor-type tyrosine-protein phosphatase C def: "A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule." [PMID:1351092, PRO:CNA] comment: Category=gene. Requested by=CL. synonym: "CD45" RELATED Gene-based [] synonym: "L-CA" EXACT [] synonym: "T200" BROAD [PRO:DNx] synonym: "ly-5" EXACT [] synonym: "PTPRC" EXACT PRO-short-label [PRO:DNx] synonym: "lymphocyte antigen 5" EXACT [] synonym: "leukocyte common antigen" EXACT [] xref: IUPHARobj:1852 xref: PIRSF:PIRSF002004 is_a: PR:000000001 ! protein [Term] id: PR:000054485 name: receptor-type tyrosine-protein phosphatase C O-glycosylated 2 (human) def: "A receptor-type tyrosine-protein phosphatase C (human) that has been O-glycosylated at the residue equivalent to Thr-167 of the amino acid sequence represented by UniProtKB:P08575-3, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P08575-3, Thr-167, MOD:00005~GNO:G53434XO." [GlyGen:P08575-3, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hPTPRC/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P08575-3, Thr-167, MOD:00005~GNO:G53434XO" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P08575 ! receptor-type tyrosine-protein phosphatase C (human) relationship: has_part GNO:G53434XO ! G53434XO relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000054484 name: receptor-type tyrosine-protein phosphatase C O-glycosylated 1 (human) def: "A receptor-type tyrosine-protein phosphatase C (human) that has been O-glycosylated at the residue equivalent to Ser-176 of the amino acid sequence represented by UniProtKB:P08575-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P08575-3, Ser-176, MOD:00002~GNO:G43417UB." [GlyGen:P08575-3, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hPTPRC/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P08575-3, Ser-176, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P08575 ! receptor-type tyrosine-protein phosphatase C (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00002 ! O-glycosyl-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000054486 name: receptor-type tyrosine-protein phosphatase C O-glycosylated 3 (human) def: "A receptor-type tyrosine-protein phosphatase C (human) that has been O-glycosylated at the residue equivalent to Thr-167 of the amino acid sequence represented by UniProtKB:P08575-3, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P08575-3, Thr-167, MOD:00005~GNO:G58001LT." [GlyGen:P08575-3, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hPTPRC/OGlyco:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P08575-3, Thr-167, MOD:00005~GNO:G58001LT" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P08575 ! receptor-type tyrosine-protein phosphatase C (human) relationship: has_part GNO:G58001LT ! G58001LT relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P06800-6 name: receptor-type tyrosine-protein phosphatase C isoform m3 (mouse) def: "A receptor-type tyrosine-protein phosphatase C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06800-6." [PRO:DNx, UniProtKB:P06800] comment: Category=organism-sequence. synonym: "mPTPRC/iso:m3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P06800-6 is_a: PR:P06800 ! receptor-type tyrosine-protein phosphatase C (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P06800-4 name: receptor-type tyrosine-protein phosphatase C isoform m1 (mouse) def: "A receptor-type tyrosine-protein phosphatase C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06800-4." [PRO:DNx, UniProtKB:P06800] comment: Category=organism-sequence. synonym: "mPTPRC/iso:m1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P06800-4 is_a: PR:P06800 ! receptor-type tyrosine-protein phosphatase C (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P06800-5 name: receptor-type tyrosine-protein phosphatase C isoform m2 (mouse) def: "A receptor-type tyrosine-protein phosphatase C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06800-5." [PRO:DNx, UniProtKB:P06800] comment: Category=organism-sequence. synonym: "mPTPRC/iso:m2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P06800-5 is_a: PR:P06800 ! receptor-type tyrosine-protein phosphatase C (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P04157 name: receptor-type tyrosine-protein phosphatase C (rat) def: "A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of rat." [OMA:P04157, PANTHER:PTHR19134:SF42, PRO:DNx] comment: Category=organism-gene. synonym: "Ptprc" RELATED Gene-based [UniProtKB:P04157] synonym: "rPTPRC" EXACT PRO-short-label [PRO:DNx] synonym: "CD45 (rat)" EXACT [UniProtKB:P04157] synonym: "L-CA (rat)" EXACT [UniProtKB:P04157] synonym: "T200 (rat)" EXACT [UniProtKB:P04157] synonym: "leukocyte common antigen (rat)" EXACT [UniProtKB:P04157] xref: UniProtKB:P04157 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000001006 ! receptor-type tyrosine-protein phosphatase C relationship: has_gene_template RGD:3451 ! Ptprc (rat) [Term] id: PR:P04157-2 name: receptor-type tyrosine-protein phosphatase C isoform r2 (rat) def: "A receptor-type tyrosine-protein phosphatase C (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04157-2." [PRO:DNx, UniProtKB:P04157] comment: Category=organism-sequence. synonym: "rPTPRC/iso:r2" EXACT PRO-short-label [PRO:DNx] synonym: "receptor-type tyrosine-protein phosphatase C isoform L-CA variant 1 (rat)" EXACT [UniProtKB:P04157] xref: UniProtKB:P04157-2 is_a: PR:P04157 ! receptor-type tyrosine-protein phosphatase C (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:000048962 name: receptor-type tyrosine-protein phosphatase C, signal peptide removed form (human) def: "A receptor-type tyrosine-protein phosphatase C (human) that has had the signal peptide removed. UniProtKB:P08575, 24-1304." [PRO:DNx, Reactome:R-HSA-197931] comment: Category=organism-modification. synonym: "PRO_0000025470" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hPTPRC/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P08575, 24-1304" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-197931 "PR:000048962 located_in GO:0005886" xref: Reactome:R-HSA-6806150 "PR:000048962 located_in GO:0030667" intersection_of: PR:P08575 ! receptor-type tyrosine-protein phosphatase C (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P35832-4 name: tyrosine-protein phosphatase 99A isoform D (fruit fly) def: "A tyrosine-protein phosphatase 99A (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35832-4." [PRO:DNx, UniProtKB:P35832] comment: Category=organism-sequence. synonym: "fly-PTPRC/iso:D" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P35832-4 is_a: PR:P35832 ! tyrosine-protein phosphatase 99A (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P08575-10 name: receptor-type tyrosine-protein phosphatase C isoform CD45RC (human) def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RC that is encoded in the genome of human." [PRO:DAN, UniProtKB:P08575] comment: Category=organism-sequence. synonym: "CD45RC (human)" EXACT [PRO:ADD, GOC:add] synonym: "hPTPRC/iso:CD45RC" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08575-10 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000025801 ! receptor-type tyrosine-protein phosphatase C isoform CD45RC [Term] id: PR:000025818 name: receptor-type tyrosine-protein phosphatase C isoform CD45RAB, signal peptide removed glycosylated form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RAB, signal peptide removed form that includes at least one glycosylated residue." [PRO:DAN] comment: Category=modification. synonym: "PTPRC/iso:CD45RAB/SigPep-/GlycoRes+" EXACT PRO-short-label [PRO:DNx] intersection_of: has_part MOD:00693 ! glycosylated residue intersection_of: PR:000025810 ! receptor-type tyrosine-protein phosphatase C isoform CD45RAB, signal peptide removed form [Term] id: PR:000025819 name: receptor-type tyrosine-protein phosphatase C isoform CD45RAC, signal peptide removed glycosylated form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RAC, signal peptide removed form that includes at least one glycosylated residue." [PRO:DAN] comment: Category=modification. synonym: "PTPRC/iso:CD45RAC/SigPep-/GlycoRes+" EXACT PRO-short-label [PRO:DNx] intersection_of: has_part MOD:00693 ! glycosylated residue intersection_of: PR:000025811 ! receptor-type tyrosine-protein phosphatase C isoform CD45RAC, signal peptide removed form [Term] id: PR:000025816 name: receptor-type tyrosine-protein phosphatase C isoform CD45RO, signal peptide removed glycosylated form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RO, signal peptide removed form that includes at least one glycosylated residue." [PRO:DAN] comment: Category=modification. synonym: "T200" BROAD [PRO:DNx] synonym: "PTPRC/iso:CD45RO/SigPep-/GlycoRes+" EXACT PRO-short-label [PRO:DNx] intersection_of: has_part MOD:00693 ! glycosylated residue intersection_of: PR:000025808 ! receptor-type tyrosine-protein phosphatase C isoform CD45RO, signal peptide removed form [Term] id: PR:000025817 name: receptor-type tyrosine-protein phosphatase C isoform CD45RC, signal peptide removed glycosylated form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RC, signal peptide removed form that includes at least one glycosylated residue." [PRO:DAN] comment: Category=modification. synonym: "PTPRC/iso:CD45RC/SigPep-/GlycoRes+" EXACT PRO-short-label [PRO:DNx] intersection_of: has_part MOD:00693 ! glycosylated residue intersection_of: PR:000025809 ! receptor-type tyrosine-protein phosphatase C isoform CD45RC, signal peptide removed form [Term] id: PR:000025814 name: receptor-type tyrosine-protein phosphatase C isoform CD45RA, signal peptide removed glycosylated form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RA, signal peptide removed form that includes at least one glycosylated residue." [PMID:1351092, PRO:CNA] comment: Category=modification. synonym: "PTPRC/iso:CD45RA/SigPep-/GlycoRes+" EXACT PRO-short-label [PRO:DNx] intersection_of: has_part MOD:00693 ! glycosylated residue intersection_of: PR:000025806 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA, signal peptide removed form [Term] id: PR:000025815 name: receptor-type tyrosine-protein phosphatase C isoform CD45RB, signal peptide removed glycosylated form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RB, signal peptide removed form that includes at least one glycosylated residue." [PMID:1351092, PRO:CNA] comment: Category=modification. synonym: "PTPRC/iso:CD45RB/SigPep-/GlycoRes+" EXACT PRO-short-label [PRO:DNx] intersection_of: has_part MOD:00693 ! glycosylated residue intersection_of: PR:000025807 ! receptor-type tyrosine-protein phosphatase C isoform CD45RB, signal peptide removed form [Term] id: PR:000025812 name: receptor-type tyrosine-protein phosphatase C isoform CD45RBC, signal peptide removed form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RBC that has had the signal peptide removed." [PRO:DAN] comment: Category=modification. synonym: "PTPRC/iso:CD45RBC/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000025804 ! receptor-type tyrosine-protein phosphatase C isoform CD45RBC intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000025813 name: receptor-type tyrosine-protein phosphatase C isoform CD45RABC, signal peptide removed glycosylated form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RABC, signal peptide removed form that includes at least one glycosylated residue." [PRO:DAN] comment: Category=modification. synonym: "B220" EXACT [] synonym: "PTPRC/iso:CD45R/SigPep-/GlycoRes+" EXACT PRO-short-label [PRO:DNx] intersection_of: has_part MOD:00693 ! glycosylated residue intersection_of: PR:000025805 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC, signal peptide removed form [Term] id: PR:000025810 name: receptor-type tyrosine-protein phosphatase C isoform CD45RAB, signal peptide removed form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RAB that has had the signal peptide removed." [PRO:DAN] comment: Category=modification. synonym: "PTPRC/iso:CD45RAB/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000025802 ! receptor-type tyrosine-protein phosphatase C isoform CD45RAB intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000025811 name: receptor-type tyrosine-protein phosphatase C isoform CD45RAC, signal peptide removed form def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RAC that has had the signal peptide removed." [PRO:DAN] comment: Category=modification. synonym: "PTPRC/iso:CD45RAC/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000025803 ! receptor-type tyrosine-protein phosphatase C isoform CD45RAC intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:P08575-9 name: receptor-type tyrosine-protein phosphatase C isoform CD45RB (human) def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RB that is encoded in the genome of human." [GOC:add, PRO:ADD, PRO:DAN] comment: Category=organism-sequence. synonym: "CD45RB (human)" EXACT [UniProtKB:P08575] synonym: "hPTPRC/iso:CD45RB" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08575-9 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001016 ! receptor-type tyrosine-protein phosphatase C isoform CD45RB [Term] id: PR:P08575-8 name: receptor-type tyrosine-protein phosphatase C isoform CD45RA (human) def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RA that is encoded in the genome of human." [GOC:add, PRO:ADD, PRO:DAN] comment: Category=organism-sequence. Requested by=CL. synonym: "CD45RA (human)" EXACT [] synonym: "hPTPRC/iso:CD45RA" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08575-8 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001015 ! receptor-type tyrosine-protein phosphatase C isoform CD45RA [Term] id: PR:P06800 name: receptor-type tyrosine-protein phosphatase C (mouse) def: "A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of mouse." [OMA:P06800, PRO:DNx] comment: Category=organism-gene. synonym: "Ly-5" RELATED Gene-based [UniProtKB:P06800] synonym: "Ptprc" RELATED Gene-based [UniProtKB:P06800] synonym: "mPTPRC" EXACT PRO-short-label [PRO:DNx] synonym: "CD45 (mouse)" EXACT [UniProtKB:P06800] synonym: "L-CA (mouse)" EXACT [UniProtKB:P06800] synonym: "T200 (mouse)" EXACT [UniProtKB:P06800] synonym: "lymphocyte antigen 5 (mouse)" EXACT [UniProtKB:P06800] synonym: "leukocyte common antigen (mouse)" EXACT [UniProtKB:P06800] xref: UniProtKB:P06800 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000001006 ! receptor-type tyrosine-protein phosphatase C relationship: has_gene_template MGI:97810 ! Ptprc (mouse) [Term] id: PR:P35832-3 name: tyrosine-protein phosphatase 99A isoform C (fruit fly) def: "A tyrosine-protein phosphatase 99A (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35832-3." [PRO:DNx, UniProtKB:P35832] comment: Category=organism-sequence. synonym: "fly-PTPRC/iso:C" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P35832-3 is_a: PR:P35832 ! tyrosine-protein phosphatase 99A (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P08575-3 name: receptor-type tyrosine-protein phosphatase C isoform CD45RABC (human) def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RABC that is encoded in the genome of human." [PRO:DAN] comment: Category=organism-sequence. synonym: "hPTPRC/iso:CD45RABC" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08575-3 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001014 ! receptor-type tyrosine-protein phosphatase C isoform CD45RABC [Term] id: PR:P08575-5 name: receptor-type tyrosine-protein phosphatase C isoform CD45RAB (human) def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RAB that is encoded in the genome of human." [PRO:DNx, UniProtKB:P08575] comment: Category=organism-sequence. synonym: "CD45RAB (human)" EXACT [PRO:ADD, GOC:add] synonym: "hPTPRC/iso:CD45RAB" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08575-5 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000025802 ! receptor-type tyrosine-protein phosphatase C isoform CD45RAB [Term] id: PR:P08575-4 name: receptor-type tyrosine-protein phosphatase C isoform CD45RO (human) def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RO that is encoded in the genome of human." [GOC:add, PRO:ADD, PRO:DAN] comment: Category=organism-sequence. synonym: "CD45RO (human)" EXACT [PRO:ADD, GOC:add] synonym: "hPTPRC/iso:CD45RO" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08575-4 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001017 ! receptor-type tyrosine-protein phosphatase C isoform CD45RO [Term] id: PR:P08575-7 name: receptor-type tyrosine-protein phosphatase C isoform CD45RBC (human) def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RBC that is encoded in the genome of human." [PRO:DNx, UniProtKB:P08575] comment: Category=organism-sequence. synonym: "CD45RBC (human)" EXACT [UniProtKB:P08575] synonym: "hPTPRC/iso:CD45RBC" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08575-7 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000025804 ! receptor-type tyrosine-protein phosphatase C isoform CD45RBC [Term] id: PR:P08575-6 name: receptor-type tyrosine-protein phosphatase C isoform CD45RAC (human) def: "A receptor-type tyrosine-protein phosphatase C isoform CD45RAC that is encoded in the genome of human." [PRO:DNx, UniProtKB:P08575] comment: Category=organism-sequence. synonym: "CD45RAC (human)" EXACT [PRO:ADD, GOC:add] synonym: "hPTPRC/iso:CD45RAC" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08575-6 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000025803 ! receptor-type tyrosine-protein phosphatase C isoform CD45RAC [Term] id: PR:000001014 name: receptor-type tyrosine-protein phosphatase C isoform CD45RABC def: "A receptor-type tyrosine-protein phosphatase C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-3 or a 1:1 ortholog thereof." [PMID:1351092, PRO:CNA, PRO:DAN] comment: Category=sequence. Requested by=CL. Note: This isoform includes the region encoded by the variable exons 4(A), 5(B), and 6(C). synonym: "B220" RELATED [] synonym: "CD45R" RELATED [] synonym: "CD45RABC" EXACT [] synonym: "PTPRC/iso:CD45RABC" EXACT PRO-short-label [PRO:DNx] is_a: PR:000001006 ! receptor-type tyrosine-protein phosphatase C [Term] id: PR:000001015 name: receptor-type tyrosine-protein phosphatase C isoform CD45RA def: "A receptor-type tyrosine-protein phosphatase C isoform CD45R that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-8 or a 1:1 ortholog thereof." [PMID:1351092, PRO:CNA, PRO:DAN] comment: Category=sequence. Requested by=CL. Note: This isoform includes the region encoded by the variable exon 4(A), and lacks the region encoded by exons 5(B) and 6(C). synonym: "CD45RA" EXACT [] synonym: "PTPRC/iso:CD45RA" EXACT PRO-short-label [PRO:DNx] is_a: PR:000050216 ! receptor-type tyrosine-protein phosphatase C isoform CD45R [Term] id: PR:000001016 name: receptor-type tyrosine-protein phosphatase C isoform CD45RB def: "A receptor-type tyrosine-protein phosphatase C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-9 or a 1:1 ortholog thereof." [PMID:1351092, PRO:CNA, PRO:DAN] comment: Category=sequence. Requested by=CL. Note: This isoform includes the region encoded by the variable exon 5(B), and lacks the region encoded by exons 4(A) and 6(C). synonym: "CD45RB" EXACT [] synonym: "PTPRC/iso:CD45RB" EXACT PRO-short-label [PRO:DNx] is_a: PR:000001006 ! receptor-type tyrosine-protein phosphatase C [Term] id: PR:000001017 name: receptor-type tyrosine-protein phosphatase C isoform CD45RO def: "A receptor-type tyrosine-protein phosphatase C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-4 or a 1:1 ortholog thereof." [PMID:1351092, PRO:CNA, PRO:DAN] comment: Category=sequence. Requested by=CL. Note: This isoform lacks the region encoded by the variable exons 4(A), 5(B), and 6(C). synonym: "T200" RELATED [] synonym: "CD45RO" EXACT [PRO:ADD, GOC:add] synonym: "180 kDa form" EXACT [] synonym: "PTPRC/iso:CD45RO" EXACT PRO-short-label [PRO:DNx] is_a: PR:000001006 ! receptor-type tyrosine-protein phosphatase C [Term] id: PR:000050324 name: receptor-type tyrosine-protein phosphatase C isoform x1 (mouse) def: "A receptor-type tyrosine-protein phosphatase C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06800-1. UniProtKB:P06800-4, 3-1293." [PRO:DNx, UniProtKB:P06800] comment: Category=organism-sequence. Note: Removed from the source database. Formerly known as isoform 1. The isoform represented by UniProtKB:P06800-1 is the same as UniProtKB:P06800-4 except with an alternative start at position 3 relative to the latter. Since the actual start codon is uncertain, we retain this class pending confirmation. synonym: "mPtprc/iso:x1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P06800-4, 3-1293" EXACT PRO-proteoform-std [PRO:DAN] synonym: "receptor-type tyrosine-protein phosphatase C isoform B220 (mouse)" EXACT [UniProtKB:P06800] is_a: PR:P06800 ! receptor-type tyrosine-protein phosphatase C (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000050325 name: receptor-type tyrosine-protein phosphatase C isoform 2 (mouse) def: "A receptor-type tyrosine-protein phosphatase C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06800-2. UniProtKB:P06800-5, 3-1250." [PRO:DAN, UniProtKB:P06800] comment: Category=organism-sequence. Note: The isoform represented by UniProtKB:P06800-2 (removed from source database) is the same as UniProtKB:P06800-5 except with an alternative start at position 3 relative to the latter. Since the actual start codon is uncertain, we retain this class pending confirmation. synonym: "mPtprc/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P06800-5, 3-1250" EXACT PRO-proteoform-std [PRO:DAN] is_a: PR:P06800 ! receptor-type tyrosine-protein phosphatase C (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus