[Term]
id: PR:Q17ST2-2
name: potassium voltage-gated channel subfamily A member 7 isoform 2 (mouse)
def: "A voltage-gated potassium channel subunit KCNA7 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mKCNA7/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "potassium voltage-gated channel subfamily A member 7 isoform Kv1.7S (mouse)" EXACT [UniProtKB:Q17ST2]
xref: UniProtKB:Q17ST2-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000980 ! voltage-gated potassium channel subunit KCNA7 isoform 2

[Term]
id: PR:000000980
name: voltage-gated potassium channel subunit KCNA7 isoform 2
def: "A voltage-gated potassium channel subunit KCNA7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q17ST2-2 or a 1:1 ortholog thereof. This form contributes to channels that are slow-inactivating and redox-insensitive." [PRO:CNA, PRO:DAN]
comment: Category=sequence. Note: This isoform contributes to channels that are slow-inactivating and redox-insensitive.
synonym: "Kv1.7S" RELATED []
synonym: "KCNA7/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000814 ! voltage-gated potassium channel subunit KCNA7

[Term]
id: PR:Q17ST2-1
name: potassium voltage-gated channel subfamily A member 7 isoform 1 (mouse)
def: "A voltage-gated potassium channel subunit KCNA7 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mKCNA7/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "potassium voltage-gated channel subfamily A member 7 isoform Kv1.7L (mouse)" EXACT [UniProtKB:Q17ST2]
xref: UniProtKB:Q17ST2-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000979 ! voltage-gated potassium channel subunit KCNA7 isoform 1

[Term]
id: PR:000000979
name: voltage-gated potassium channel subunit KCNA7 isoform 1
def: "A voltage-gated potassium channel subunit KCNA7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q17ST2-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence. Note: This isoform contains an Hx20CxCC motif--resembling a metal coordination motif--in the N-terminal region. The N terminus appears to be a key component in the redox sensitivity of Kv1.7 channel inactivation. This form contributes to channels that inactivate fast and are sensitive to redox modulation.
synonym: "Kv1.7L" RELATED []
synonym: "KCNA7/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "Potassium voltage-gated channel subfamily A member 7 isoform 1" RELATED []
is_a: PR:000000814 ! voltage-gated potassium channel subunit KCNA7

[Term]
id: PR:000000814
name: voltage-gated potassium channel subunit KCNA7
def: "A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA7 gene or a 1:1 ortholog thereof. The Kv1.7 channel has properties similar to the ultrarapidly activating IKur current in the heart. It can coassemble with other Kv1 subunits." [PRO:CNA]
comment: Category=gene.
synonym: "KCNA7" EXACT PRO-short-label [PRO:DNx]
synonym: "Kcnc7" RELATED Gene-based []
synonym: "voltage-gated potassium channel subunit Kv1.7" EXACT []
xref: IUPHARobj:544
is_a: PR:000000709 ! shaker-related voltage-gated potassium channel alpha subunit

[Term]
id: PR:Q17ST2
name: potassium voltage-gated channel subfamily A member 7 (mouse)
def: "A voltage-gated potassium channel subunit KCNA7 that is encoded in the genome of mouse." [OMA:Q17ST2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Kcna7" RELATED Gene-based [UniProtKB:Q17ST2]
synonym: "Kcnc7" RELATED Gene-based [UniProtKB:Q17ST2]
synonym: "mKCNA7" EXACT PRO-short-label [PRO:DNx]
synonym: "voltage-gated potassium channel subunit Kv1.7 (mouse)" EXACT [UniProtKB:Q17ST2]
xref: UniProtKB:Q17ST2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000814 ! voltage-gated potassium channel subunit KCNA7
relationship: has_gene_template MGI:96664 ! Kcna7 (mouse)

[Term]
id: PR:Q96RP8-1
name: potassium voltage-gated channel subfamily A member 7 isoform 1 (human)
def: "A voltage-gated potassium channel subunit KCNA7 isoform 2 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hKCNA7/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q96RP8-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000980 ! voltage-gated potassium channel subunit KCNA7 isoform 2

[Term]
id: PR:Q96RP8
name: potassium voltage-gated channel subfamily A member 7 (human)
def: "A voltage-gated potassium channel subunit KCNA7 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q96RP8]
comment: Category=organism-gene.
synonym: "KCNA7" RELATED Gene-based [UniProtKB:Q96RP8]
synonym: "hKCNA7" EXACT PRO-short-label [PRO:DNx]
synonym: "voltage-gated potassium channel subunit Kv1.7 (human)" EXACT [UniProtKB:Q96RP8]
xref: UniProtKB:Q96RP8
xref: Reactome:R-HSA-977468 "PR:Q96RP8 located_in GO:0005886"
xref: DTO:01100186
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000814 ! voltage-gated potassium channel subunit KCNA7
relationship: has_gene_template HGNC:6226 ! KCNA7 (human)