[Term]
id: PR:000000810
name: voltage-gated potassium channel subunit KCNA2
def: "A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA2 gene or a 1:1 ortholog thereof. The Kv1.2 channel is involved in maintaining membrane potential, modulating electrical excitability in neurons and muscle. It can coassemble with other Kv1 subunits." [PMID:16382104]
comment: Category=gene.
synonym: "MK2" RELATED []
synonym: "NGK1" EXACT []
synonym: "KCNA2" EXACT PRO-short-label [PRO:DNx]
synonym: "voltage-gated K(+) channel HuKIV" EXACT []
synonym: "voltage-gated potassium channel HBK5" EXACT []
synonym: "voltage-gated potassium channel subunit Kv1.2" EXACT []
xref: IUPHARobj:539
is_a: PR:000000709 ! shaker-related voltage-gated potassium channel alpha subunit

[Term]
id: PR:P16389
name: potassium voltage-gated channel subfamily A member 2 (human)
def: "A voltage-gated potassium channel subunit KCNA2 that is encoded in the genome of human." []
comment: Category=organism-gene.
synonym: "KCNA2" RELATED Gene-based [UniProtKB:P16389]
synonym: "hKCNA2" EXACT PRO-short-label [PRO:DNx]
synonym: "NGK1 (human)" EXACT [UniProtKB:P16389]
synonym: "voltage-gated K(+) channel HuKIV (human)" EXACT [UniProtKB:P16389]
synonym: "voltage-gated potassium channel HBK5 (human)" EXACT [UniProtKB:P16389]
synonym: "voltage-gated potassium channel subunit Kv1.2 (human)" EXACT [UniProtKB:P16389]
xref: Reactome:R-HSA-977477 "PR:P16389 located_in GO:0005886"
xref: DTO:01100181
xref: UniProtKB:P16389
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000810 ! voltage-gated potassium channel subunit KCNA2
relationship: has_gene_template HGNC:6220 ! KCNA2 (human)

[Term]
id: PR:P16389-1
name: potassium voltage-gated channel subfamily A member 2 isoform 1 (human)
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hKCNA2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16389-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000972 ! voltage-gated potassium channel subunit KCNA2 isoform 1

[Term]
id: PR:P16389-2
name: potassium voltage-gated channel subfamily A member 2 isoform h2 (human)
def: "A potassium voltage-gated channel subfamily A member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16389-2." [PRO:DNx, UniProtKB:P16389]
comment: Category=organism-sequence.
synonym: "hKCNA2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16389-2
is_a: PR:P16389 ! potassium voltage-gated channel subfamily A member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036584
name: voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human)
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 in human. UniProtKB:P16389-1, Tyr-132, MOD:00048." [PMID:15215309, PRO:CNA]
comment: Category=organism-modification.
synonym: "hKCNA2/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16389-1, Tyr-132, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001000 ! voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000036587
name: voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human)
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in human. UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA]
comment: Category=organism-modification.
synonym: "hKCNA2/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001001 ! voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2
relationship: has_part MOD:00046 ! O-phospho-L-serine