[Term]
id: PR:Q12809
name: potassium voltage-gated channel subfamily H member 2 (human)
def: "A voltage-gated potassium channel KCNH2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q12809]
comment: Category=organism-gene.
synonym: "ERG" RELATED Gene-based [UniProtKB:Q12809]
synonym: "ERG1" RELATED Gene-based [UniProtKB:Q12809]
synonym: "HERG" RELATED Gene-based [UniProtKB:Q12809]
synonym: "H-ERG" EXACT [UniProtKB:Q12809]
synonym: "KCNH2" RELATED Gene-based [UniProtKB:Q12809]
synonym: "hERG1" EXACT [UniProtKB:Q12809]
synonym: "hERG-1" EXACT [UniProtKB:Q12809]
synonym: "hKCNH2" EXACT PRO-short-label [PRO:DNx]
synonym: "ERG-1 (human)" EXACT [UniProtKB:Q12809]
synonym: "Eag homolog (human)" EXACT [UniProtKB:Q12809]
synonym: "Eag-related protein 1 (human)" EXACT [UniProtKB:Q12809]
synonym: "ether-a-go-go-related protein 1 (human)" EXACT [UniProtKB:Q12809]
synonym: "ether-a-go-go-related gene potassium channel 1 (human)" EXACT [UniProtKB:Q12809]
synonym: "voltage-gated potassium channel subunit Kv11.1 (human)" EXACT [UniProtKB:Q12809]
xref: UniProtKB:Q12809
xref: Reactome:R-HSA-977529 "PR:Q12809 located_in GO:0005886"
xref: DTO:01100206
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000791 ! voltage-gated potassium channel KCNH2
relationship: has_gene_template HGNC:6251 ! KCNH2 (human)

[Term]
id: PR:Q12809-2
name: potassium voltage-gated channel subfamily H member 2 isoform B (human)
def: "A voltage-gated potassium channel KCNH2 isoform B that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q12809]
comment: Category=organism-sequence.
synonym: "hKCNH2/iso:B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12809-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000958 ! voltage-gated potassium channel KCNH2 isoform B

[Term]
id: PR:000045393
name: voltage-gated potassium channel KCNH2 isoform A unphosphorylated form (human)
def: "A potassium voltage-gated channel subfamily H member 2 isoform A (human) that lacks phosphorylated residues." [PMID:10837251, PRO:CNA]
comment: Category=organism-modification.
synonym: "hKCNH2/iso:A/PhosRes-" EXACT PRO-short-label [PRO:DAN]
intersection_of: lacks_part MOD:00696 ! phosphorylated residue
intersection_of: PR:Q12809-1 ! potassium voltage-gated channel subfamily H member 2 isoform A (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045392
name: voltage-gated potassium channel KCNH2 isoform A non-glycosylated 1 (human)
def: "A voltage-gated potassium channel KCNH2 isoform A non-glycosylated 1 in human. UniProtKB:Q12809-1, Asn-598, PR:000026291." [PMID:12063277, PRO:CNA]
comment: Category=organism-modification.
synonym: "hKCNH2/iso:A/UnGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q12809-1, Asn-598, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000045391 ! voltage-gated potassium channel KCNH2 isoform A non-glycosylated 1

[Term]
id: PR:000000791
name: voltage-gated potassium channel KCNH2
def: "A voltage-gated potassium channel Erg alpha subunit that is a translation product of the human KCNH2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "ERG" RELATED Gene-based []
synonym: "ERG1" RELATED Gene-based []
synonym: "HERG" RELATED Gene-based []
synonym: "ERG-1" EXACT []
synonym: "KCNH2" EXACT PRO-short-label [PRO:DNx]
synonym: "KHCN2" RELATED [PRO:CNA]
synonym: "Eag homolog" EXACT []
synonym: "Eag-related protein 1" EXACT []
synonym: "ether-a-go-go-related protein 1" EXACT []
synonym: "ether-a-go-go-related gene potassium channel 1" EXACT []
synonym: "voltage-gated potassium channel subunit Kv11.1" EXACT []
xref: IUPHARobj:572
is_a: PR:000000721 ! voltage-gated potassium channel Erg alpha subunit

[Term]
id: PR:Q12809-1
name: potassium voltage-gated channel subfamily H member 2 isoform A (human)
def: "A voltage-gated potassium channel KCNH2 isoform A that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hKCNH2/iso:A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12809-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000957 ! voltage-gated potassium channel KCNH2 isoform A

[Term]
id: PR:000036581
name: voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1 (human)
def: "A voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1 in human. UniProtKB:Q12809-1, Asn-598, MOD:00160." [PMID:12063277, PRO:CNA]
comment: Category=organism-modification.
synonym: "hKCNH2/iso:1/Glyco:1" EXACT [PRO:DNx]
synonym: "hKCNH2/iso:A/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q12809-1, Asn-598, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "voltage-gated potassium channel KCNH2 isoform 1 glycosylated 1 (human)" EXACT [PRO:CNA]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000998 ! voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine

[Term]
id: PR:000036583
name: voltage-gated potassium channel KCNH2 isoform A phosphorylated 1 (human)
def: "A voltage-gated potassium channel KCNH2 isoform A phosphorylated 1 in human." [PMID:10837251, PRO:CNA]
comment: Category=organism-modification.
synonym: "hKCNH2/iso:1/Phos:1" EXACT [PRO:DNx]
synonym: "hKCNH2/iso:A/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "voltage-gated potassium channel KCNH2 isoform 1 phosphorylated 1 (human)" EXACT [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000999 ! voltage-gated potassium channel KCNH2 isoform A phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:Q12809-5
name: potassium voltage-gated channel subfamily H member 2 isoform A-USO (human)
def: "A voltage-gated potassium channel KCNH2 isoform A-USO that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q12809]
comment: Category=organism-sequence.
synonym: "hKCNH2/iso:A-USO" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12809-5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000959 ! voltage-gated potassium channel KCNH2 isoform A-USO

[Term]
id: PR:Q12809-4
name: potassium voltage-gated channel subfamily H member 2 isoform h4 (human)
def: "A potassium voltage-gated channel subfamily H member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12809-4." [PRO:DNx, UniProtKB:Q12809]
comment: Category=organism-sequence.
synonym: "hKCNH2/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12809-4
is_a: PR:Q12809 ! potassium voltage-gated channel subfamily H member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q12809-7
name: potassium voltage-gated channel subfamily H member 2 isoform h3.1 (human)
def: "A potassium voltage-gated channel subfamily H member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12809-7." [PRO:DNx, UniProtKB:Q12809]
comment: Category=organism-sequence.
synonym: "hKCNH2/iso:h3.1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12809-7
is_a: PR:Q12809 ! potassium voltage-gated channel subfamily H member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q12809-6
name: potassium voltage-gated channel subfamily H member 2 isoform B-USO (human)
def: "A potassium voltage-gated channel subfamily H member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12809-6." [PRO:DNx, UniProtKB:Q12809]
comment: Category=organism-sequence.
synonym: "hKCNH2/iso:B-USO" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12809-6
is_a: PR:Q12809 ! potassium voltage-gated channel subfamily H member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens