[Term] id: PR:000000801 name: voltage-gated potassium channel KCNV1 isoform 1 def: "A voltage-gated potassium channel KCNV1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PIU1-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] comment: Category=sequence. synonym: "KCNV1/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000000725 ! voltage-gated potassium channel KCNV1 [Term] id: PR:Q6PIU1-1 name: potassium voltage-gated channel subfamily V member 1 isoform 1 (human) def: "A voltage-gated potassium channel KCNV1 isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hKCNV1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6PIU1-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000801 ! voltage-gated potassium channel KCNV1 isoform 1 [Term] id: PR:000000725 name: voltage-gated potassium channel KCNV1 def: "A voltage-gated potassium channel alpha subunit that is a translation product of the human KCNV1 gene or a 1:1 ortholog thereof. It has an atypical S6 segment containing the structural elements that modify inactivation of Kv2 channels. Similarly to KCNF1, KCNV1 and KCNS, KCNV2 subunits are not able to form functional channels on their own. Also in common with these modulatory subunits, it lacks the conserved PxP motif located in the distal part of S6. In this class the motif is PIA. The alteration of the PxP motif seems to be an important determinant of the regulatory function of modulatory subunits. It modulates the activity of KCNB1 and KCNB2 channels by changing kinetics and levels of expression and by shifting the half-inactivation potential to more polarized values." [PMID:16382104] comment: Category=gene. synonym: "KCNV1" EXACT PRO-short-label [PRO:DNx] synonym: "neuronal potassium channel alpha subunit HNKA" EXACT [] synonym: "voltage-gated potassium channel subunit Kv8.1" EXACT [] xref: IUPHARobj:565 xref: PANTHER:PTHR11537:SF38 is_a: PR:000000685 ! voltage-gated potassium channel alpha subunit [Term] id: PR:Q9XXD1 name: probable voltage-gated potassium channel subunit kvs-4 (worm) def: "A voltage-gated potassium channel KCNV1 that is encoded in the genome of worm." [PRO:DNx, UniProtKB:Q9XXD1] comment: Category=organism-gene. synonym: "kvs-4" RELATED Gene-based [UniProtKB:Q9XXD1] synonym: "Y48A6B.6" RELATED Gene-based [UniProtKB:Q9XXD1] synonym: "KCNV1 (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9XXD1 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000000725 ! voltage-gated potassium channel KCNV1 relationship: has_gene_template WormBase:WBGene00012967 ! kvs-4 (worm) [Term] id: PR:Q6PIU1 name: potassium voltage-gated channel subfamily V member 1 (human) def: "A voltage-gated potassium channel KCNV1 that is encoded in the genome of human." [] comment: Category=organism-gene. synonym: "KCNV1" RELATED Gene-based [UniProtKB:Q6PIU1] synonym: "hKCNV1" EXACT PRO-short-label [PRO:DNx] synonym: "neuronal potassium channel alpha subunit HNKA (human)" EXACT [UniProtKB:Q6PIU1] synonym: "voltage-gated potassium channel subunit Kv8.1 (human)" EXACT [UniProtKB:Q6PIU1] xref: Reactome:R-HSA-977508 "PR:Q6PIU1 located_in GO:0005886" xref: DTO:01100243 xref: UniProtKB:Q6PIU1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000725 ! voltage-gated potassium channel KCNV1 relationship: has_gene_template HGNC:18861 ! KCNV1 (human) [Term] id: PR:P97557 name: potassium voltage-gated channel subfamily V member 1 (rat) def: "A voltage-gated potassium channel KCNV1 that is encoded in the genome of rat." [OMA:P97557, PANTHER:PTHR11537:SF38, PRO:DNx] comment: Category=organism-gene. synonym: "Kcnv1" RELATED Gene-based [UniProtKB:P97557] synonym: "rKCNV1" EXACT PRO-short-label [PRO:DNx] synonym: "voltage-gated potassium channel subunit Kv8.1 (rat)" EXACT [UniProtKB:P97557] synonym: "voltage-gated potassium channel subunit Kv2.3r (rat)" EXACT [UniProtKB:P97557] xref: UniProtKB:P97557 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000000725 ! voltage-gated potassium channel KCNV1 relationship: has_gene_template RGD:621264 ! Kcnv1 (rat) [Term] id: PR:Q8BZN2 name: potassium voltage-gated channel subfamily V member 1 (mouse) def: "A voltage-gated potassium channel KCNV1 that is encoded in the genome of mouse." [OMA:Q8BZN2, PRO:DNx] comment: Category=organism-gene. synonym: "Kcnv1" RELATED Gene-based [UniProtKB:Q8BZN2] synonym: "mKCNV1" EXACT PRO-short-label [PRO:DNx] synonym: "voltage-gated potassium channel subunit Kv8.1 (mouse)" EXACT [UniProtKB:Q8BZN2] xref: UniProtKB:Q8BZN2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000000725 ! voltage-gated potassium channel KCNV1 relationship: has_gene_template MGI:1914748 ! Kcnv1 (mouse) [Term] id: PR:Q9XXD1-2 name: probable voltage-gated potassium channel subunit kvs-4 isoform b (worm) def: "A probable voltage-gated potassium channel subunit kvs-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9XXD1-2." [PRO:DNx, UniProtKB:Q9XXD1] comment: Category=organism-sequence. synonym: "KCNV1/iso:b (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9XXD1-2 is_a: PR:Q9XXD1 ! probable voltage-gated potassium channel subunit kvs-4 (worm) relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans [Term] id: PR:Q9XXD1-1 name: probable voltage-gated potassium channel subunit kvs-4 isoform a (worm) def: "A probable voltage-gated potassium channel subunit kvs-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9XXD1-1." [PRO:DNx, UniProtKB:Q9XXD1] comment: Category=organism-sequence. synonym: "KCNV1/iso:a (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9XXD1-1 is_a: PR:Q9XXD1 ! probable voltage-gated potassium channel subunit kvs-4 (worm) relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans