[Term]
id: PR:O88704
name: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (mouse)
def: "A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 that is encoded in the genome of mouse." [OMA:O88704, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hac2" RELATED Gene-based [UniProtKB:O88704]
synonym: "Hcn1" RELATED Gene-based [UniProtKB:O88704]
synonym: "Bcng1" RELATED Gene-based [UniProtKB:O88704]
synonym: "mHCN1" EXACT PRO-short-label [PRO:DNx]
synonym: "HAC-2 (mouse)" EXACT [UniProtKB:O88704]
synonym: "BCNG-1 (mouse)" EXACT [UniProtKB:O88704]
synonym: "brain cyclic nucleotide-gated channel 1 (mouse)" EXACT [UniProtKB:O88704]
synonym: "hyperpolarization-activated cation channel 2 (mouse)" EXACT [UniProtKB:O88704]
xref: UniProtKB:O88704
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000705 ! potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
relationship: has_gene_template MGI:1096392 ! Hcn1 (mouse)

[Term]
id: PR:000000984
name: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1
def: "A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 glycosylated form with N-glycosylation at the N-linked glycosylation consensus sequence (Nx[ST]) in the extracellular domain between S5 and S6 transmembrane segments. Example: UniProtKB:O88704-1, Asn-327, MOD:00160." [PMID:17988239]
comment: Category=modification.
synonym: "HCN1/iso:1/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000935 ! potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 glycosylated form
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine

[Term]
id: PR:Q9JKB0
name: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (rat)
def: "A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 that is encoded in the genome of rat." [OMA:Q9JKB0, PANTHER:PTHR10217:SF373, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hcn1" RELATED Gene-based [UniProtKB:Q9JKB0]
synonym: "rHCN1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9JKB0
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000705 ! potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
relationship: has_gene_template RGD:620688 ! Hcn1 (rat)

[Term]
id: PR:O60741
name: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (human)
def: "A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O60741]
comment: Category=organism-gene.
synonym: "HCN1" RELATED Gene-based [UniProtKB:O60741]
synonym: "BCNG1" RELATED Gene-based [UniProtKB:O60741]
synonym: "hHCN1" EXACT PRO-short-label [PRO:DNx]
synonym: "BCNG-1 (human)" EXACT [UniProtKB:O60741]
synonym: "brain cyclic nucleotide-gated channel 1 (human)" EXACT [UniProtKB:O60741]
xref: Reactome:R-HSA-977503 "PR:O60741 located_in GO:0005886"
xref: DTO:01100144
xref: UniProtKB:O60741
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000705 ! potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
relationship: has_gene_template HGNC:4845 ! HCN1 (human)

[Term]
id: PR:000000755
name: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1
def: "A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88704-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "HCN1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000705 ! potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

[Term]
id: PR:000000705
name: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
def: "A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein that is a translation product of the human HCN1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "HCN1" EXACT PRO-short-label [PRO:DNx]
synonym: "Hac2" RELATED Gene-based []
synonym: "BCNG1" RELATED Gene-based []
synonym: "HAC-2" EXACT []
synonym: "BCNG-1" EXACT []
synonym: "brain cyclic nucleotide-gated channel 1" EXACT []
synonym: "hyperpolarization-activated cation channel 2" EXACT []
xref: IUPHARobj:400
is_a: PR:000000676 ! potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein

[Term]
id: PR:O88704-1
name: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse)
def: "A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mHCN1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O88704-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000755 ! potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1

[Term]
id: PR:000036573
name: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 (mouse)
def: "A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 in mouse. UniProtKB:O88704-1, Asn-327, MOD:00160." [PMID:12928435, PRO:CNA, PRO:DAN]
comment: Category=organism-modification.
synonym: "mHCN1/iso:1/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O88704-1, Asn-327, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000984 ! potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine

[Term]
id: PR:000000935
name: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 glycosylated form
def: "A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 that includes at least one glycosylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "HCN1/iso:1/GlycoRes+" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part MOD:00693 ! glycosylated residue
intersection_of: PR:000000755 ! potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1