[Term]
id: PR:000000748
name: cyclic nucleotide-gated cation channel alpha-3 sequence variant P163L (human)
def: "A cyclic nucleotide-gated cation channel alpha-3 (human) that has a Leu residue at the position equivalent to Pro-163 of the amino acid sequence represented by UniProtKB:Q16281-1. Example: UniProtKB:Q16281-1, Pro-163, CHEBI:30006." [PMID:9662398, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hCNGA3/var:P163L" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16281-1, Pro-163, CHEBI:30006" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "cyclic nucleotide-gated cation channel alpha-3 sequence variant 8 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_010903
is_a: PR:Q16281 ! cyclic nucleotide-gated cation channel alpha-3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000696
name: cyclic nucleotide-gated cation channel alpha-3
def: "A cyclic nucleotide-gated channel alpha subunit that is a translation product of the human CNGA3 gene or a 1:1 ortholog thereof. These proteins are the alpha subunits of the cone cyclic nucleotide-gated cation channel. This channel generates the light-evoked electrical responses of cone photoreceptors." [PRO:CNA]
comment: Category=gene.
synonym: "CNG3" EXACT []
synonym: "CNCG3" RELATED Gene-based []
synonym: "CNG-3" EXACT []
synonym: "CNGA3" EXACT PRO-short-label [PRO:DNx]
synonym: "CNG channel alpha-3" EXACT []
synonym: "cyclic nucleotide-gated channel alpha-3" EXACT []
synonym: "cone photoreceptor cGMP-gated channel subunit alpha" EXACT []
xref: IUPHARobj:396
is_a: PR:000000673 ! cyclic nucleotide-gated channel alpha subunit

[Term]
id: PR:000000743
name: cyclic nucleotide-gated cation channel alpha-3 sequence variant G557R (human)
def: "A cyclic nucleotide-gated cation channel alpha-3 (human) that has an Arg residue at the position equivalent to Gly-557 of the amino acid sequence represented by UniProtKB:Q16281-1. Example: UniProtKB:Q16281-1, Gly-557, CHEBI:29952." [PMID:9662398, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence. Note: This residue is located within the cytoplasmic cyclic nucleotide binding domain (CNBD).
synonym: "hCNGA3/var:G557R" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16281-1, Gly-557, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "cyclic nucleotide-gated cation channel alpha-3 sequence variant 3 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_010909
is_a: PR:Q16281 ! cyclic nucleotide-gated cation channel alpha-3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000742
name: cyclic nucleotide-gated cation channel alpha-3 sequence variant T291R (human)
def: "A cyclic nucleotide-gated cation channel alpha-3 (human) that has an Arg residue at the position equivalent to Thr-291 of the amino acid sequence represented by UniProtKB:Q16281-1. Example: UniProtKB:Q16281-1, Thr-291, CHEBI:29952." [PMID:9662398, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence. Note: This residue is located within the segment S4.
synonym: "hCNGA3/var:T291R" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16281-1, Thr-291, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "cyclic nucleotide-gated cation channel alpha-3 sequence variant 2 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_010906
is_a: PR:Q16281 ! cyclic nucleotide-gated cation channel alpha-3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000741
name: cyclic nucleotide-gated cation channel alpha-3 sequence variant R283Q (human)
def: "A cyclic nucleotide-gated cation channel alpha-3 (human) that has a Gln residue at the position equivalent to Arg-283 of the amino acid sequence represented by UniProtKB:Q16281-1. Example: UniProtKB:Q16281-1, Arg-283, CHEBI:30011." [PMID:9662398, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence. Note: This residue is located within the segment S4.
synonym: "hCNGA3/var:R283Q" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16281-1, Arg-283, CHEBI:30011" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "cyclic nucleotide-gated cation channel alpha-3 sequence variant 1 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_010904
is_a: PR:Q16281 ! cyclic nucleotide-gated cation channel alpha-3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000747
name: cyclic nucleotide-gated cation channel alpha-3 sequence variant R410W (human)
def: "A cyclic nucleotide-gated cation channel alpha-3 (human) that has a Trp residue at the position equivalent to Arg-410 of the amino acid sequence represented by UniProtKB:Q16281-1. Example: UniProtKB:Q16281-1, Arg-410, CHEBI:29954." [PMID:9662398, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence. Note: This residue is located at the cytoplasmic C-terminus.
synonym: "hCNGA3/var:R410W" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16281-1, Arg-410, CHEBI:29954" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "cyclic nucleotide-gated cation channel alpha-3 sequence variant 7 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_010910
is_a: PR:Q16281 ! cyclic nucleotide-gated cation channel alpha-3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000746
name: cyclic nucleotide-gated cation channel alpha-3 sequence variant F547L (human)
def: "A cyclic nucleotide-gated cation channel alpha-3 (human) that has a Leu residue at the position equivalent to Phe-547 of the amino acid sequence represented by UniProtKB:Q16281-1. Example: UniProtKB:Q16281-1, Phe-547, CHEBI:30006." [PMID:9662398, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence. Note: This residue is located within the cytoplasmic cyclic nucleotide binding domain (CNBD).
synonym: "hCNGA3/var:F547L" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16281-1, Phe-547, CHEBI:30006" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "cyclic nucleotide-gated cation channel alpha-3 sequence variant 6 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_010908
is_a: PR:Q16281 ! cyclic nucleotide-gated cation channel alpha-3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000745
name: cyclic nucleotide-gated cation channel alpha-3 sequence variant R283W (human)
def: "A cyclic nucleotide-gated cation channel alpha-3 (human) that has a Trp residue at the position equivalent to Arg-283 of the amino acid sequence represented by UniProtKB:Q16281-1. Example: UniProtKB:Q16281-1, Arg-283, CHEBI:29954." [PMID:9662398, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence. Note: This residue is located within the segment S4.
synonym: "hCNGA3/var:R283W" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16281-1, Arg-283, CHEBI:29954" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "cyclic nucleotide-gated cation channel alpha-3 sequence variant 5 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_010905
is_a: PR:Q16281 ! cyclic nucleotide-gated cation channel alpha-3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000744
name: cyclic nucleotide-gated cation channel alpha-3 sequence variant V529M (human)
def: "A cyclic nucleotide-gated cation channel alpha-3 (human) that has a Met residue at the position equivalent to Val-529 of the amino acid sequence represented by UniProtKB:Q16281-1. Example: UniProtKB:Q16281-1, Val-529, CHEBI:16044." [PMID:9662398, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence. Note: This residue is located within the cytoplasmic cyclic nucleotide binding domain (CNBD).
synonym: "hCNGA3/var:V529M" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16281-1, Val-529, CHEBI:16044" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "cyclic nucleotide-gated cation channel alpha-3 sequence variant 4 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_010907
is_a: PR:Q16281 ! cyclic nucleotide-gated cation channel alpha-3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16281-3
name: cyclic nucleotide-gated cation channel alpha-3 isoform h3 (human)
def: "A cyclic nucleotide-gated cation channel alpha-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16281-3." [PRO:DNx, UniProtKB:Q16281]
comment: Category=organism-sequence.
synonym: "hCNGA3/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16281-3
is_a: PR:Q16281 ! cyclic nucleotide-gated cation channel alpha-3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16281
name: cyclic nucleotide-gated cation channel alpha-3 (human)
def: "A cyclic nucleotide-gated cation channel alpha-3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q16281]
comment: Category=organism-gene.
synonym: "CNCG3" RELATED Gene-based [UniProtKB:Q16281]
synonym: "CNGA3" RELATED Gene-based [UniProtKB:Q16281]
synonym: "hCNGA3" EXACT PRO-short-label [PRO:DNx]
synonym: "CNG3 (human)" EXACT [UniProtKB:Q16281]
synonym: "CNG-3 (human)" EXACT [UniProtKB:Q16281]
synonym: "CNG channel alpha-3 (human)" EXACT [UniProtKB:Q16281]
synonym: "cyclic nucleotide-gated channel alpha-3 (human)" EXACT [UniProtKB:Q16281]
synonym: "cone photoreceptor cGMP-gated channel subunit alpha (human)" EXACT [UniProtKB:Q16281]
xref: DTO:01100087
xref: UniProtKB:Q16281
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000696 ! cyclic nucleotide-gated cation channel alpha-3
relationship: has_gene_template HGNC:2150 ! CNGA3 (human)

[Term]
id: PR:Q16281-2
name: cyclic nucleotide-gated cation channel alpha-3 isoform h2 (human)
def: "A cyclic nucleotide-gated cation channel alpha-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16281-2." [PRO:DNx, UniProtKB:Q16281]
comment: Category=organism-sequence.
synonym: "hCNGA3/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16281-2
is_a: PR:Q16281 ! cyclic nucleotide-gated cation channel alpha-3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16281-1
name: cyclic nucleotide-gated cation channel alpha-3 isoform 1 (human)
def: "A cyclic nucleotide-gated cation channel alpha-3 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hCNGA3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16281-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000739 ! cyclic nucleotide-gated cation channel alpha-3 isoform 1