[Term]
id: PR:000000686
name: cGMP-gated cation channel alpha-1
def: "A cyclic nucleotide-gated channel alpha subunit that is a translation product of the human CNGA1 gene or a 1:1 ortholog thereof. In the retina, these proteins can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors." [PRO:CNA]
comment: Category=gene.
synonym: "CNCG" RELATED Gene-based []
synonym: "CNG1" EXACT []
synonym: "CNCG1" RELATED Gene-based []
synonym: "CNG-1" EXACT []
synonym: "CNGA1" EXACT PRO-short-label [PRO:DNx]
synonym: "CNG channel alpha-1" EXACT []
synonym: "cyclic nucleotide-gated channel alpha-1" EXACT []
synonym: "cyclic nucleotide-gated cation channel 1" EXACT []
synonym: "cyclic nucleotide-gated channel, photoreceptor" EXACT []
synonym: "rod photoreceptor cGMP-gated channel subunit alpha" EXACT []
xref: IUPHARobj:394
is_a: PR:000000673 ! cyclic nucleotide-gated channel alpha subunit