[Term]
id: PR:000000686
name: cGMP-gated cation channel alpha-1
def: "A cyclic nucleotide-gated channel alpha subunit that is a translation product of the human CNGA1 gene or a 1:1 ortholog thereof. In the retina, these proteins can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors." [PRO:CNA]
comment: Category=gene.
synonym: "CNCG" RELATED Gene-based []
synonym: "CNG1" EXACT []
synonym: "CNCG1" RELATED Gene-based []
synonym: "CNG-1" EXACT []
synonym: "CNGA1" EXACT PRO-short-label [PRO:DNx]
synonym: "CNG channel alpha-1" EXACT []
synonym: "cyclic nucleotide-gated channel alpha-1" EXACT []
synonym: "cyclic nucleotide-gated cation channel 1" EXACT []
synonym: "cyclic nucleotide-gated channel, photoreceptor" EXACT []
synonym: "rod photoreceptor cGMP-gated channel subunit alpha" EXACT []
xref: IUPHARobj:394
is_a: PR:000000673 ! cyclic nucleotide-gated channel alpha subunit

[Term]
id: PR:Q62927
name: cGMP-gated cation channel alpha-1 (rat)
def: "A cGMP-gated cation channel alpha-1 that is encoded in the genome of rat." [OMA:Q62927, PANTHER:PTHR10217:SF387, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cncg" RELATED Gene-based [UniProtKB:Q62927]
synonym: "Cncg1" RELATED Gene-based [UniProtKB:Q62927]
synonym: "Cnga1" RELATED Gene-based [UniProtKB:Q62927]
synonym: "rCNGA1" EXACT PRO-short-label [PRO:DNx]
synonym: "CNG1 (rat)" EXACT [UniProtKB:Q62927]
synonym: "CNG-1 (rat)" EXACT [UniProtKB:Q62927]
synonym: "CNG channel alpha-1 (rat)" EXACT [UniProtKB:Q62927]
synonym: "cyclic nucleotide-gated channel alpha-1 (rat)" EXACT [UniProtKB:Q62927]
synonym: "cyclic nucleotide-gated cation channel 1 (rat)" EXACT [UniProtKB:Q62927]
synonym: "cyclic nucleotide-gated channel, photoreceptor (rat)" EXACT [UniProtKB:Q62927]
synonym: "rod photoreceptor cGMP-gated channel subunit alpha (rat)" EXACT [UniProtKB:Q62927]
xref: UniProtKB:Q62927
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000686 ! cGMP-gated cation channel alpha-1
relationship: has_gene_template RGD:621815 ! Cnga1 (rat)