[Term]
id: PR:000000686
name: cGMP-gated cation channel alpha-1
def: "A cyclic nucleotide-gated channel alpha subunit that is a translation product of the human CNGA1 gene or a 1:1 ortholog thereof. In the retina, these proteins can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors." [PRO:CNA]
comment: Category=gene.
synonym: "CNCG" RELATED Gene-based []
synonym: "CNG1" EXACT []
synonym: "CNCG1" RELATED Gene-based []
synonym: "CNG-1" EXACT []
synonym: "CNGA1" EXACT PRO-short-label [PRO:DNx]
synonym: "CNG channel alpha-1" EXACT []
synonym: "cyclic nucleotide-gated channel alpha-1" EXACT []
synonym: "cyclic nucleotide-gated cation channel 1" EXACT []
synonym: "cyclic nucleotide-gated channel, photoreceptor" EXACT []
synonym: "rod photoreceptor cGMP-gated channel subunit alpha" EXACT []
xref: IUPHARobj:394
is_a: PR:000000673 ! cyclic nucleotide-gated channel alpha subunit

[Term]
id: PR:P29974
name: cGMP-gated cation channel alpha-1 (mouse)
def: "A cGMP-gated cation channel alpha-1 that is encoded in the genome of mouse." [OMA:P29974, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cncg" RELATED Gene-based [UniProtKB:P29974]
synonym: "Cncg1" RELATED Gene-based [UniProtKB:P29974]
synonym: "Cnga1" RELATED Gene-based [UniProtKB:P29974]
synonym: "mCNGA1" EXACT PRO-short-label [PRO:DNx]
synonym: "CNG1 (mouse)" EXACT [UniProtKB:P29974]
synonym: "CNG-1 (mouse)" EXACT [UniProtKB:P29974]
synonym: "CNG channel alpha-1 (mouse)" EXACT [UniProtKB:P29974]
synonym: "cyclic nucleotide-gated channel alpha-1 (mouse)" EXACT [UniProtKB:P29974]
synonym: "cyclic nucleotide-gated cation channel 1 (mouse)" EXACT [UniProtKB:P29974]
synonym: "cyclic nucleotide-gated channel, photoreceptor (mouse)" EXACT [UniProtKB:P29974]
synonym: "rod photoreceptor cGMP-gated channel subunit alpha (mouse)" EXACT [UniProtKB:P29974]
xref: UniProtKB:P29974
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000686 ! cGMP-gated cation channel alpha-1
relationship: has_gene_template MGI:88436 ! Cnga1 (mouse)

[Term]
id: PR:P29974-1
name: cGMP-gated cation channel alpha-1 isoform 1 (mouse)
def: "A cGMP-gated cation channel alpha-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mCNGA1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P29974-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000737 ! cGMP-gated cation channel alpha-1 isoform 1