[Term]
id: PR:A2RTF1-1
name: cation channel sperm-associated auxiliary subunit beta isoform 1 (mouse)
def: "A cation channel sperm-associated auxiliary subunit beta isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mCATSPERB/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:A2RTF1-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000695 ! cation channel sperm-associated auxiliary subunit beta isoform 1

[Term]
id: PR:000000672
name: cation channel sperm-associated auxiliary subunit beta
def: "A protein that is a translation product of the human CATSPERB gene or a 1:1 ortholog thereof. Members of this class are auxiliary proteins to the CatSper channel. They have four putative transmembrane-spanning domains. In mammals, four CatSper ion channel subunit genes (CatSpers 1-4) are required for sperm cell hyperactivation and male fertility. The four proteins assemble (presumably as a tetramer) to form a sperm-specific, alkalinization-activated Ca(2+)-selective channel." [PMID:17478420, PRO:CNA]
comment: Category=gene.
synonym: "CATSPERB" EXACT PRO-short-label [PRO:DNx]
synonym: "C14orf161" RELATED Gene-based []
synonym: "CatSper-beta" EXACT []
xref: PIRSF:PIRSF038543
is_a: PR:000000001 ! protein

[Term]
id: PR:A2RTF1
name: cation channel sperm-associated auxiliary subunit beta (mouse)
def: "A cation channel sperm-associated auxiliary subunit beta that is encoded in the genome of mouse." [OMA:A2RTF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "Catsperb" RELATED Gene-based [UniProtKB:A2RTF1]
synonym: "mCATSPERB" EXACT PRO-short-label [PRO:DNx]
synonym: "CatSper-beta (mouse)" EXACT [UniProtKB:A2RTF1]
xref: UniProtKB:A2RTF1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000672 ! cation channel sperm-associated auxiliary subunit beta
relationship: has_gene_template MGI:2443988 ! Catsperb (mouse)