[Term]
id: PR:000000282
name: growth/differentiation factor 7
def: "A growth/differentiation factor that is a translation product of the human GDF7 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "GDF7" EXACT PRO-short-label [PRO:DNx]
synonym: "GDF-7" EXACT []
xref: PANTHER:PTHR11848:SF42
is_a: PR:000000098 ! growth/differentiation factor

[Term]
id: PR:P43029-2
name: growth/differentiation factor 7 isoform 2 (mouse)
def: "A growth/differentiation factor 7 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mGDF7/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43029-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000443 ! growth/differentiation factor 7 isoform 2

[Term]
id: PR:000000442
name: growth/differentiation factor 7 isoform 1
def: "A growth/differentiation factor 7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43029-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "GDF7/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000282 ! growth/differentiation factor 7

[Term]
id: PR:000000443
name: growth/differentiation factor 7 isoform 2
def: "A growth/differentiation factor 7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43029-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence. Note: This form has a shorter propeptide as compared to isoform 1.
synonym: "GDF7/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000282 ! growth/differentiation factor 7

[Term]
id: PR:P43029-1
name: growth/differentiation factor 7 isoform 1 (mouse)
def: "A growth/differentiation factor 7 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mGDF7/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43029-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000442 ! growth/differentiation factor 7 isoform 1

[Term]
id: PR:000000641
name: growth/differentiation factor 7 isoform 1 cleaved 1
def: "A growth/differentiation factor 7 isoform 1, signal peptide removed form that has been processed by subsequent removal of the propeptide, yielding the mature protein." [PRO:CNA]
comment: Category=modification.
synonym: "GDF7/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000021915 ! growth/differentiation factor 7 isoform 1, signal peptide removed form
intersection_of: lacks_part SO:0001062 ! propeptide

[Term]
id: PR:P43029
name: growth/differentiation factor 7 (mouse)
def: "A growth/differentiation factor 7 that is encoded in the genome of mouse." [OMA:P43029, PRO:DNx]
comment: Category=organism-gene.
synonym: "Gdf7" RELATED Gene-based [UniProtKB:P43029]
synonym: "Gdf-7" RELATED Gene-based [UniProtKB:P43029]
synonym: "mGDF7" EXACT PRO-short-label [PRO:DNx]
synonym: "GDF-7 (mouse)" EXACT [UniProtKB:P43029]
xref: UniProtKB:P43029
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000282 ! growth/differentiation factor 7
relationship: has_gene_template MGI:95690 ! Gdf7 (mouse)

[Term]
id: PR:000021930
name: growth/differentiation factor 7 proteolytic cleavage product
def: "A growth/differentiation factor 7 that has been processed by proteolytic cleavage." [PRO:DAN]
comment: Category=modification.
synonym: "GDF7/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000000282 ! growth/differentiation factor 7

[Term]
id: PR:000036544
name: growth/differentiation factor 7 isoform 1 cleaved 1 (mouse)
def: "A growth/differentiation factor 7 isoform 1 cleaved 1 in mouse. UniProtKB:P43029-1, 316-461." [PMID:12741987, PRO:CNA]
comment: Category=organism-modification.
synonym: "PRO_0000033925" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "mGDF7/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P43029-1, 316-461" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000641 ! growth/differentiation factor 7 isoform 1 cleaved 1

[Term]
id: PR:000021915
name: growth/differentiation factor 7 isoform 1, signal peptide removed form
def: "A growth/differentiation factor 7 isoform 1 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "GDF7/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000000442 ! growth/differentiation factor 7 isoform 1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:Q7Z4P5
name: growth/differentiation factor 7 (human)
def: "A growth/differentiation factor 7 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q7Z4P5]
comment: Category=organism-gene.
synonym: "GDF7" RELATED Gene-based [UniProtKB:Q7Z4P5]
synonym: "hGDF7" EXACT PRO-short-label [PRO:DNx]
synonym: "GDF-7 (human)" EXACT [UniProtKB:Q7Z4P5]
xref: UniProtKB:Q7Z4P5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000282 ! growth/differentiation factor 7
relationship: has_gene_template HGNC:4222 ! GDF7 (human)