[Term]
id: PR:000036538
name: TGF-beta 3 isoform 1 cleaved 3 (mouse)
def: "A TGF-beta 3 isoform 1 cleaved 3 in mouse, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P17125-1, 30-298, 299-410." [PMID:1821856, PRO:CNA, PRO:DAN]
comment: Category=organism-modification.
synonym: "mTGFB3/iso:1/Clv:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P17125-1, 30-298, 299-410" EXACT PRO-proteoform-std [PRO:DAN]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000636 ! TGF-beta 3 isoform 1 cleaved 3

[Term]
id: PR:Q07258
name: transforming growth factor beta-3 proprotein (rat)
def: "A TGF-beta 3 that is encoded in the genome of rat." [OMA:Q07258, PANTHER:PTHR11848:SF34, PRO:DNx]
comment: Category=organism-gene.
synonym: "Tgfb3" RELATED Gene-based [UniProtKB:Q07258]
synonym: "Tgf-b3" RELATED Gene-based [UniProtKB:Q07258]
synonym: "rTGFB3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07258
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000184 ! TGF-beta 3
relationship: has_gene_template RGD:3851 ! Tgfb3 (rat)

[Term]
id: PR:000000636
name: TGF-beta 3 isoform 1 cleaved 3
def: "A TGF-beta 3 isoform 1, signal peptide removed form that has been processed by subsequent cleavage at the dibasic cleavage site rendering the latency associated peptide (LAP) and the mature protein non-covalently bound." [PRO:CNA]
comment: Category=modification.
synonym: "TGFB3/iso:1/Clv:3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000021910 ! TGF-beta 3 isoform 1, signal peptide removed form
relationship: output_of GO:0016485 ! protein processing

[Term]
id: PR:000000635
name: TGF-beta 3 isoform 1 cleaved 2
def: "A TGF-beta 3 isoform 1, signal peptide removed form that has been processed by proteolytic cleavage to remove the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP)." [PMID:11821050]
comment: Category=modification.
synonym: "TGFB3 lap" RELATED []
synonym: "TGFB3/iso:1/Clv:2" EXACT PRO-short-label [PRO:DNx]
synonym: "TGFB3 latent associated peptide" RELATED []
is_a: PR:000021910 ! TGF-beta 3 isoform 1, signal peptide removed form
relationship: output_of GO:0016485 ! protein processing

[Term]
id: PR:000000634
name: TGF-beta 3 isoform 1 cleaved 1
def: "A TGF-beta 3 isoform 1 that has been processed by proteolytic cleavage and released from the latent complex. This form is the active mature peptide." [PRO:CNA]
comment: Category=modification.
synonym: "TGFB3/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000406 ! TGF-beta 3 isoform 1
relationship: output_of GO:0016485 ! protein processing

[Term]
id: PR:000000406
name: TGF-beta 3 isoform 1
def: "A TGF-beta 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10600-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "TGFB3/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000184 ! TGF-beta 3

[Term]
id: PR:000018294
name: TGF-beta 3 proteolytic cleavage product
def: "A TGF-beta 3 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "TGFB3/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000000184 ! TGF-beta 3

[Term]
id: PR:P10600-2
name: transforming growth factor beta-3 isoform h2 (human)
def: "A transforming growth factor beta-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10600-2." [PRO:DNx, UniProtKB:P10600]
comment: Category=organism-sequence.
synonym: "hTGFB3/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10600-2
is_a: PR:P10600 ! transforming growth factor beta-3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036537
name: TGF-beta 3 isoform 1 cleaved 1 (mouse)
def: "A TGF-beta 3 isoform 1 cleaved 1 in mouse. UniProtKB:P17125-1, 299-410." [PMID:1821856, PRO:CNA]
comment: Category=organism-modification.
synonym: "PRO_0000033799" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "mTGFB3/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P17125-1, 299-410" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000634 ! TGF-beta 3 isoform 1 cleaved 1

[Term]
id: PR:000036536
name: TGF-beta 3 isoform 1 cleaved 1 (human)
def: "A TGF-beta 3 isoform 1 cleaved 1 in human. UniProtKB:P10600-1, 301-412." [PMID:18243111, PRO:CNA]
comment: Category=organism-modification.
synonym: "PRO_0000033797" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hTGFB3/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10600-1, 301-412" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-65942 "PR:000036536 located_in GO:0031093"
xref: Reactome:R-HSA-114707 "PR:000036536 located_in GO:0005576"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000634 ! TGF-beta 3 isoform 1 cleaved 1

[Term]
id: PR:P10600
name: transforming growth factor beta-3 (human)
def: "A TGF-beta 3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P10600]
comment: Category=organism-gene.
synonym: "TGFB3" RELATED Gene-based [UniProtKB:P10600]
synonym: "hTGFB3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10600
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000184 ! TGF-beta 3
relationship: has_gene_template HGNC:11769 ! TGFB3 (human)

[Term]
id: PR:P10600-1
name: transforming growth factor beta-3 isoform 1 (human)
def: "A TGF-beta 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hTGFB3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10600-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000406 ! TGF-beta 3 isoform 1

[Term]
id: PR:P17125-1
name: transforming growth factor beta-3 isoform 1 (mouse)
def: "A TGF-beta 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mTGFB3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P17125-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000406 ! TGF-beta 3 isoform 1

[Term]
id: PR:P16047
name: transforming growth factor beta-3 proprotein (chicken)
def: "A TGF-beta 3 that is encoded in the genome of chicken." [OMA:P16047, PRO:DNx]
comment: Category=organism-gene.
synonym: "TGFB3" RELATED Gene-based [UniProtKB:P16047]
synonym: "chick-TGFB3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16047
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000000184 ! TGF-beta 3
relationship: has_gene_template NCBIGene:396438 ! TGFB3 (chicken)

[Term]
id: PR:P17125
name: transforming growth factor beta-3 (mouse)
def: "A TGF-beta 3 that is encoded in the genome of mouse." [OMA:P17125, PRO:DAN]
comment: Category=organism-gene.
synonym: "Tgfb3" RELATED Gene-based [UniProtKB:P17125]
synonym: "mTGFB3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P17125
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000184 ! TGF-beta 3
relationship: has_gene_template MGI:98727 ! Tgfb3 (mouse)

[Term]
id: PR:000000184
name: TGF-beta 3
def: "A TGF-beta that is a translation product of the human TGFB3 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "TGFB3" EXACT PRO-short-label [PRO:DNx]
synonym: "TGF-beta-3" EXACT []
xref: PANTHER:PTHR11848:SF34
is_a: PR:000000046 ! TGF-beta

[Term]
id: PR:000021910
name: TGF-beta 3 isoform 1, signal peptide removed form
def: "A TGF-beta 3 isoform 1 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "TGFB3/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000000406 ! TGF-beta 3 isoform 1
intersection_of: lacks_part SO:0000418 ! signal_peptide