[Term]
id: PR:000018289
name: GTP-binding protein RhoA proteolytic cleavage product
def: "A GTP-binding protein RhoA that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "RHOA/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000000176 ! GTP-binding protein RhoA

[Term]
id: PR:P61585
name: transforming protein RhoA (cow)
def: "A GTP-binding protein RhoA that is encoded in the genome of cow." [OMA:P61585, PRO:DAN]
comment: Category=organism-gene.
synonym: "ARHA" RELATED Gene-based [UniProtKB:P61585]
synonym: "RHOA" RELATED Gene-based [UniProtKB:P61585]
synonym: "RHO12" RELATED Gene-based [UniProtKB:P61585]
synonym: "Gb (cow)" EXACT [UniProtKB:P61585]
synonym: "cow-RHOA" EXACT PRO-short-label [PRO:DNx]
synonym: "p21 (cow)" BROAD [UniProtKB:P61585]
xref: UniProtKB:P61585
intersection_of: only_in_taxon NCBITaxon:9913 ! Bos taurus
intersection_of: PR:000000176 ! GTP-binding protein RhoA
relationship: has_gene_template NCBIGene:338049 ! RHOA (cow)

[Term]
id: PR:P61585-1
name: transforming protein RhoA isoform 1 (cow)
def: "A GTP-binding protein RhoA isoform 1 that is encoded in the genome of cow." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "cow-RHOA/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P61585-1
intersection_of: only_in_taxon NCBITaxon:9913 ! Bos taurus
intersection_of: PR:000000395 ! GTP-binding protein RhoA isoform 1

[Term]
id: PR:Q9QUI0-1
name: transforming protein RhoA isoform 1 (mouse)
def: "A GTP-binding protein RhoA isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mRHOA/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9QUI0-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000395 ! GTP-binding protein RhoA isoform 1

[Term]
id: PR:000036520
name: GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 (human)
def: "A GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 in human. UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119." [PMID:1383236, PMID:16773203, PRO:CNA, PRO:DAN]
comment: Category=organism-modification. Note: Species evidence in reference 1383236 is traced back to reference 2491843. Evidence=(ECO:0000305, based on UniProtKB:P61586, for region 1-190).
synonym: "hRHOA/iso:1/IpCysEst:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000030411, Cys-190, MOD:01119" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000615 ! GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1
relationship: has_part MOD:01119 ! S-geranylgeranyl-L-cysteine methyl ester
relationship: lacks_part SO:0001062 ! propeptide

[Term]
id: PR:000036521
name: GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 (cow)
def: "A GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 in cow. UniProtKB:P61585-1, 1-190, Cys-190, MOD:01119." [PMID:1903193, PRO:CNA, PRO:DAN]
comment: Category=organism-modification. Evidence=(ECO:0000305, based on UniProtKB:P61585, for region 1-190).
synonym: "cow-RHOA/iso:1/IpCysEst:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000030407, Cys-190, MOD:01119" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P61585-1, 1-190, Cys-190, MOD:01119" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9913 ! Bos taurus
intersection_of: PR:000000615 ! GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1
relationship: has_part MOD:01119 ! S-geranylgeranyl-L-cysteine methyl ester
relationship: lacks_part SO:0001062 ! propeptide

[Term]
id: PR:P61589
name: transforming protein RhoA (rat)
def: "A GTP-binding protein RhoA that is encoded in the genome of rat." [OMA:P61589, PRO:DNx]
comment: Category=organism-gene.
synonym: "Arha" RELATED Gene-based [UniProtKB:P61589]
synonym: "Rhoa" RELATED Gene-based [UniProtKB:P61589]
synonym: "Arha2" RELATED Gene-based [UniProtKB:P61589]
synonym: "rRHOA" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P61589
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000176 ! GTP-binding protein RhoA
relationship: has_gene_template RGD:619921 ! Rhoa (rat)

[Term]
id: PR:000000176
name: GTP-binding protein RhoA
def: "A Rho-related small GTPase that is a translation product of the human RHOA gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "h12" EXACT []
synonym: "ARHA" RELATED Gene-based []
synonym: "RHOA" EXACT PRO-short-label [PRO:DNx]
synonym: "ARH12" RELATED Gene-based []
synonym: "Arha2" RELATED Gene-based []
synonym: "RHO12" RELATED Gene-based []
synonym: "rho cDNA clone 12" EXACT []
is_a: PR:000000122 ! Rho-related small GTPase

[Term]
id: PR:P48148
name: Ras-like GTP-binding protein Rho1 (fruit fly)
def: "A GTP-binding protein RhoA that is encoded in the genome of fruit fly." [PRO:CNA]
comment: Category=organism-gene.
synonym: "Rho1" RELATED Gene-based [UniProtKB:P48148]
synonym: "CG8416" RELATED Gene-based [UniProtKB:P48148]
synonym: "fly-RHOA" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48148
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000000176 ! GTP-binding protein RhoA
relationship: has_gene_template FlyBase:FBgn0014020 ! Rho1 (fruit fly)

[Term]
id: PR:P61586-1
name: transforming protein RhoA isoform 1 (human)
def: "A GTP-binding protein RhoA isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hRHOA/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P61586-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000395 ! GTP-binding protein RhoA isoform 1

[Term]
id: PR:P06780
name: GTP-binding protein RHO1 (yeast)
def: "A GTP-binding protein RhoA that is encoded in the genome of yeast." [OMA:P06780, PRO:DNx]
comment: Category=organism-gene.
synonym: "RHO1" RELATED Gene-based [UniProtKB:P06780]
synonym: "yRHOA" EXACT PRO-short-label [PRO:DNx]
synonym: "P9325.3" RELATED Gene-based [UniProtKB:P06780]
synonym: "YPR165W" RELATED Gene-based [UniProtKB:P06780]
synonym: "Rho-type GTPase 1 (yeast)" EXACT [UniProtKB:P06780]
xref: UniProtKB:P06780
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000000176 ! GTP-binding protein RhoA
relationship: has_gene_template SGD:S000006369 ! RHO1 (yeast)

[Term]
id: PR:Q7T2E8
name: Rho-related GTP-binding protein RhoA-C (zebrafish)
def: "A GTP-binding protein RhoA that is encoded in the genome of zebrafish." [PRO:CNA]
comment: Category=organism-gene.
synonym: "rhoac" RELATED Gene-based [UniProtKB:Q7T2E8]
synonym: "z-RHOA" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q7T2E8
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000000176 ! GTP-binding protein RhoA
relationship: has_gene_template ZFIN:ZDB-GENE-040426-2665 ! rhoac (zebrafish)

[Term]
id: PR:Q22038
name: Ras-like GTP-binding protein rhoA (worm)
def: "A GTP-binding protein RhoA that is encoded in the genome of worm." [OMA:Q22038, PRO:DNx]
comment: Category=organism-gene.
synonym: "rhoa" RELATED Gene-based [UniProtKB:Q22038]
synonym: "rho-1" RELATED Gene-based [UniProtKB:Q22038]
synonym: "Y51H4A.3" RELATED Gene-based [UniProtKB:Q22038]
synonym: "RHOA (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q22038
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000000176 ! GTP-binding protein RhoA
relationship: has_gene_template WormBase:WBGene00004357 ! rho-1 (worm)

[Term]
id: PR:000000615
name: GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1
def: "A GTP-binding protein RhoA isoform 1 that has been geranylgeranylated on the Cys residue within the C-terminal CaaX motif (a=an aliphatic residue, X=any residue), followed by cleavage of aaX and methylation of the Cys. Example: UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119." [PMID:16773203, PMID:1905729, PRO:CNA]
comment: Category=modification.
synonym: "RHOA/iso:1/IpCysEst:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000395 ! GTP-binding protein RhoA isoform 1
relationship: has_part MOD:01119 ! S-geranylgeranyl-L-cysteine methyl ester
relationship: lacks_part SO:0001062 ! propeptide

[Term]
id: PR:000000395
name: GTP-binding protein RhoA isoform 1
def: "A GTP-binding protein RhoA that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61586-1 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "RHOA/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000176 ! GTP-binding protein RhoA

[Term]
id: PR:Q9QUI0
name: transforming protein RhoA (mouse)
def: "A GTP-binding protein RhoA that is encoded in the genome of mouse." [OMA:Q9QUI0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Arha" RELATED Gene-based [UniProtKB:Q9QUI0]
synonym: "Rhoa" RELATED Gene-based [UniProtKB:Q9QUI0]
synonym: "Arha2" RELATED Gene-based [UniProtKB:Q9QUI0]
synonym: "mRHOA" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9QUI0
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000176 ! GTP-binding protein RhoA
relationship: has_gene_template MGI:1096342 ! Rhoa (mouse)

[Term]
id: PR:P61586
name: transforming protein RhoA (human)
def: "A GTP-binding protein RhoA that is encoded in the genome of human." [PRO:CNA, UniProtKB:P61586]
comment: Category=organism-gene.
synonym: "ARHA" RELATED Gene-based [UniProtKB:P61586]
synonym: "RHOA" RELATED Gene-based [UniProtKB:P61586]
synonym: "ARH12" RELATED Gene-based [UniProtKB:P61586]
synonym: "RHO12" RELATED Gene-based [UniProtKB:P61586]
synonym: "hRHOA" EXACT PRO-short-label [PRO:DNx]
synonym: "h12 (human)" EXACT [UniProtKB:P61586]
synonym: "Rho cDNA clone 12 (human)" EXACT [UniProtKB:P61586]
xref: UniProtKB:P61586
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000176 ! GTP-binding protein RhoA
relationship: has_gene_template HGNC:667 ! RHOA (human)