[Term]
id: PR:000000095
name: tumor necrosis factor ligand superfamily member 6
def: "A tumor necrosis factor, TNF-like that is a translation product of the human FASLG gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "gld" RELATED Gene-based []
synonym: "APTL" EXACT []
synonym: "FASL" RELATED Gene-based []
synonym: "CD178" EXACT []
synonym: "CD95L" RELATED Gene-based []
synonym: "FASLG" EXACT PRO-short-label [PRO:DNx]
synonym: "CD95-L" EXACT []
synonym: "TNFSF6" RELATED Gene-based []
synonym: "APT1LG1" RELATED Gene-based []
synonym: "fas ligand" EXACT []
synonym: "CD95 ligand" EXACT []
synonym: "fas antigen ligand" EXACT []
synonym: "fas ligand, TNF-like" EXACT []
synonym: "apoptosis antigen ligand" EXACT []
xref: PANTHER:PTHR11471:SF7
is_a: PR:000000033 ! tumor necrosis factor, TNF-like

[Term]
id: PR:P48023
name: tumor necrosis factor ligand superfamily member 6 (human)
def: "A tumor necrosis factor ligand superfamily member 6 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P48023]
comment: Category=organism-gene.
synonym: "FASL" RELATED Gene-based [UniProtKB:P48023]
synonym: "CD95L" RELATED Gene-based [UniProtKB:P48023]
synonym: "FASLG" RELATED Gene-based [UniProtKB:P48023]
synonym: "TNFSF6" RELATED Gene-based [UniProtKB:P48023]
synonym: "hFASLG" EXACT PRO-short-label [PRO:DNx]
synonym: "APT1LG1" RELATED Gene-based [UniProtKB:P48023]
synonym: "APTL (human)" EXACT [UniProtKB:P48023]
synonym: "CD178 (human)" EXACT [UniProtKB:P48023]
synonym: "CD95-L (human)" EXACT [UniProtKB:P48023]
synonym: "Fas ligand (human)" EXACT [UniProtKB:P48023]
synonym: "CD95 ligand (human)" EXACT [UniProtKB:P48023]
synonym: "Fas antigen ligand (human)" EXACT [UniProtKB:P48023]
synonym: "apoptosis antigen ligand (human)" EXACT [UniProtKB:P48023]
xref: Reactome:R-HSA-66212 "PR:P48023 located_in GO:0005576"
xref: UniProtKB:P48023
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000095 ! tumor necrosis factor ligand superfamily member 6
relationship: has_gene_template HGNC:11936 ! FASLG (human)

[Term]
id: PR:000036458
name: tumor necrosis factor ligand superfamily member 6 isoform FasL N-glycosylated 1 (human)
def: "A tumor necrosis factor ligand superfamily member 6 isoform FasL N-glycosylated 1 in human. UniProtKB:P48023-1, Asn-184/Asn-250/Asn-260, MOD:00160." [PMID:9405425, PRO:CNA, PRO:DAN]
comment: Category=organism-modification.
synonym: "hFASLG/iso:FasL/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48023-1, Asn-184/Asn-250/Asn-260, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000546 ! tumor necrosis factor ligand superfamily member 6 isoform FasL N-glycosylated 1
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine

[Term]
id: PR:000036459
name: tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form (human)
def: "A tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form in human. UniProtKB:P48023-1, 130-281." [PMID:7536672, PMID:9228058, PMID:9396774, PMID:9405425, PRO:CNA]
comment: Category=organism-modification.
synonym: "PRO_0000034501" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P48023-1, 130-281" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "hFASLG/iso:FasL/Clv:soluble" EXACT PRO-short-label [PRO:DAN]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000547 ! tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form

[Term]
id: PR:000036782
name: tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (human)
def: "A tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L that is encoded in the genome of human. The variation occurs at the position equivalent to Phe-275 of the amino acid sequence represented by UniProtKB:P48023-1. UniProtKB:P48023-1, Phe-275, CHEBI:30006." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "gld" RELATED []
synonym: "hFASLG/iso:FasL/var:F273L" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48023-1, Phe-275, CHEBI:30006" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "FASLG isoform 1 sequence variant 1 (human)" EXACT [PRO:DNx]
synonym: "FASLG isoform FasL sequence variant 1 (human)" EXACT [PRO:DNx]
synonym: "tumor necrosis factor ligand superfamily member 6 isoform 1 sequence variant 1 (human)" EXACT [PRO:DNx]
synonym: "tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant 1 (human)" EXACT [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000278 ! tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L

[Term]
id: PR:P48023-1
name: tumor necrosis factor ligand superfamily member 6 isoform FasL (human)
def: "A tumor necrosis factor ligand superfamily member 6 isoform FasL that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hFASLG/iso:FasL" EXACT PRO-short-label [PRO:DNx]
synonym: "FASLG isoform 1 (human)" EXACT [PRO:DNx]
synonym: "tumor necrosis factor ligand superfamily member 6 isoform 1 (human)" EXACT [PRO:DNx]
xref: UniProtKB:P48023-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000276 ! tumor necrosis factor ligand superfamily member 6 isoform FasL

[Term]
id: PR:P48023-2
name: tumor necrosis factor ligand superfamily member 6 isoform h2 (human)
def: "A tumor necrosis factor ligand superfamily member 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48023-2." [PRO:DNx, UniProtKB:P48023]
comment: Category=organism-sequence.
synonym: "hFASLG/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48023-2
is_a: PR:P48023 ! tumor necrosis factor ligand superfamily member 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens