[Term]
id: PR:Q04771
name: activin receptor type-1 (human)
def: "An activin receptor type-1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q04771]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "ACVR1" RELATED Gene-based [UniProtKB:Q04771]
synonym: "hACVR1" EXACT PRO-short-label [PRO:DNx]
synonym: "ACVRLK2" RELATED Gene-based [UniProtKB:Q04771]
synonym: "SKR1 (human)" EXACT [UniProtKB:Q04771]
synonym: "ALK-2 (human)" EXACT [UniProtKB:Q04771]
synonym: "TSR-I (human)" BROAD [UniProtKB:Q04771]
synonym: "ACTR-I (human)" EXACT [UniProtKB:Q04771]
synonym: "activin receptor type I (human)" EXACT [UniProtKB:Q04771]
synonym: "activin receptor-like kinase 2 (human)" EXACT [UniProtKB:Q04771]
synonym: "TGF-B superfamily receptor type I (human)" BROAD [UniProtKB:Q04771]
synonym: "serine/threonine-protein kinase receptor R1 (human)" EXACT [UniProtKB:Q04771]
xref: DTO:03100012
xref: UniProtKB:Q04771
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000067 ! activin receptor type-1
relationship: has_gene_template HGNC:171 ! ACVR1 (human)

[Term]
id: PR:P37172
name: activin receptor type-1 (mouse)
def: "An activin receptor type-1 that is encoded in the genome of mouse." [OMA:P37172, PRO:DNx]
comment: Category=organism-gene.
synonym: "Acvr1" RELATED Gene-based [UniProtKB:P37172]
synonym: "Tgfb1" RELATED Gene-based [UniProtKB:P37172]
synonym: "mACVR1" EXACT PRO-short-label [PRO:DNx]
synonym: "Acvrlk2" RELATED Gene-based [UniProtKB:P37172]
synonym: "SKR1 (mouse)" EXACT [UniProtKB:P37172]
synonym: "TSR-I (mouse)" RELATED [UniProtKB:P37172]
synonym: "ACTR-I (mouse)" EXACT [UniProtKB:P37172]
synonym: "TSK-7L (mouse)" EXACT [UniProtKB:P37172]
synonym: "activin receptor type I (mouse)" EXACT [UniProtKB:P37172]
synonym: "TGF-B superfamily receptor type I (mouse)" RELATED [UniProtKB:P37172]
synonym: "serine/threonine-protein kinase receptor R1 (mouse)" EXACT [UniProtKB:P37172]
xref: UniProtKB:P37172
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000067 ! activin receptor type-1
relationship: has_gene_template MGI:87911 ! Acvr1 (mouse)

[Term]
id: PR:Q04771-1
name: activin receptor type-1 isoform 1 (human)
def: "An activin receptor type-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hACVR1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q04771-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000199 ! activin receptor type-1 isoform 1

[Term]
id: PR:000000524
name: activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1
def: "An activin receptor type-1 isoform 1, signal peptide removed phosphorylated form in which the phosphorylation occurs at Ser/Thr residues within GS-motif by the activated activin receptor type-2 (PR:000000528, PR:000000529)." [PRO:CNA]
comment: Category=modification.
synonym: "ACVR1/iso:1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000411 ! activin receptor type-1 isoform 1, signal peptide removed phosphorylated form
relationship: has_part MOD:00696 ! phosphorylated residue

[Term]
id: PR:000000411
name: activin receptor type-1 isoform 1, signal peptide removed phosphorylated form
def: "An activin receptor type-1 isoform 1, signal peptide removed form that includes at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "ACVR1/iso:1/SigPep-/PhosRes+" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:000021938 ! activin receptor type-1 isoform 1, signal peptide removed form

[Term]
id: PR:P37172-1
name: activin receptor type-1 isoform 1 (mouse)
def: "An activin receptor type-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mACVR1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P37172-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000199 ! activin receptor type-1 isoform 1

[Term]
id: PR:Q90ZK6
name: activin receptor type-1 (chicken)
def: "An activin receptor type-1 that is encoded in the genome of chicken." [OMA:Q90ZK6, PANTHER:PTHR23255:SF14, PRO:DNx]
comment: Category=organism-gene.
synonym: "ACVR1" RELATED Gene-based [UniProtKB:Q90ZK6]
synonym: "chick-ACVR1" EXACT PRO-short-label [PRO:DNx]
synonym: "type I TGF B receptor (chicken)" EXACT [UniProtKB:Q90ZK6]
synonym: "activin receptor type I (chicken)" EXACT [UniProtKB:Q90ZK6]
xref: UniProtKB:Q90ZK6
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000000067 ! activin receptor type-1
relationship: has_gene_template NCBIGene:395246 ! ACVR1 (chicken)

[Term]
id: PR:000000067
name: activin receptor type-1
def: "A TGF-beta superfamily receptor type-1 that is a translation product of the human ACVR1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "SKR1" EXACT []
synonym: "ACVR1" EXACT PRO-short-label [PRO:DNx]
synonym: "ALK-2" EXACT []
synonym: "TSR-I" RELATED []
synonym: "Tgfb1" RELATED Gene-based []
synonym: "ACTR-I" EXACT []
synonym: "TSK-7L" EXACT []
synonym: "ACVRLK2" RELATED Gene-based []
synonym: "activin receptor type I" EXACT []
synonym: "activin receptor-like kinase 2" EXACT []
synonym: "TGF-B superfamily receptor type I" RELATED []
synonym: "serine/threonine-protein kinase receptor R1" EXACT []
xref: IUPHARobj:1785
is_a: PR:000000006 ! TGF-beta superfamily receptor type-1

[Term]
id: PR:000036436
name: activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (mouse)
def: "An activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 in mouse." [PMID:11376112, PRO:CNA]
comment: Category=organism-modification.
synonym: "mACVR1/iso:1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000524 ! activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1
relationship: has_part MOD:00696 ! phosphorylated residue

[Term]
id: PR:000000199
name: activin receptor type-1 isoform 1
def: "An activin receptor type-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04771-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "ACVR1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000067 ! activin receptor type-1

[Term]
id: PR:000000200
name: activin receptor type-1 sequence variant R206H (human)
def: "An activin receptor type-1 (human) that has a His residue at the position equivalent to Arg-206 of the amino acid sequence represented by UniProtKB:Q04771. This variation is located within the GS-motif. UniProtKB:Q04771, Arg-206, CHEBI:29979." [PMID:8397373, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hACVR1/var:R206H" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q04771, Arg-206, CHEBI:29979" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "activin receptor type-1 sequence variant 1 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_028244
is_a: PR:Q04771 ! activin receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P80201
name: activin receptor type-1 (rat)
def: "An activin receptor type-1 that is encoded in the genome of rat." [OMA:P80201, PANTHER:PTHR23255:SF14, PRO:DNx]
comment: Category=organism-gene.
synonym: "Acvr1" RELATED Gene-based [UniProtKB:P80201]
synonym: "rACVR1" EXACT PRO-short-label [PRO:DNx]
synonym: "Acvrlk2" RELATED Gene-based [UniProtKB:P80201]
synonym: "SKR1 (rat)" EXACT [UniProtKB:P80201]
synonym: "TSR-I (rat)" RELATED [UniProtKB:P80201]
synonym: "ACTR-I (rat)" EXACT [UniProtKB:P80201]
synonym: "activin receptor type I (rat)" EXACT [UniProtKB:P80201]
synonym: "TGF-B superfamily receptor type I (rat)" RELATED [UniProtKB:P80201]
synonym: "serine/threonine-protein kinase receptor R1 (rat)" EXACT [UniProtKB:P80201]
xref: UniProtKB:P80201
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000067 ! activin receptor type-1
relationship: has_gene_template RGD:620200 ! Acvr1 (rat)

[Term]
id: PR:000021938
name: activin receptor type-1 isoform 1, signal peptide removed form
def: "An activin receptor type-1 isoform 1 that has had the signal peptide removed to yield the mature protein." [PRO:DAN]
comment: Category=modification.
synonym: "ACVR1/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000000199 ! activin receptor type-1 isoform 1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000036435
name: activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human)
def: "An activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 in human." [PMID:8242742, PMID:8389764, PMID:8397373, PRO:CNA]
comment: Category=organism-modification.
synonym: "hACVR1/iso:1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000524 ! activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1
relationship: has_part MOD:00696 ! phosphorylated residue