[Term]
id: PR:000000037
name: BMP receptor type-2
def: "A TGF-beta superfamily receptor type-2 with activin receptor domain that is a translation product of the human BMPR2 gene or a 1:1 ortholog thereof. Bone morphogenetic protein (BMP) signals are transmitted by type 2 and type 1 serine/threonine kinase receptors. Type 2 receptors phosphorylate and activate type 1 receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators." [PRO:CNA]
comment: Category=gene.
synonym: "PPH1" RELATED Gene-based []
synonym: "BMPR2" EXACT PRO-short-label [PRO:DNx]
synonym: "BRK-3" EXACT []
synonym: "BMPR-2" EXACT []
synonym: "BMPR-II" EXACT []
synonym: "BMP type-2 receptor" EXACT []
synonym: "BMP type II receptor" EXACT []
synonym: "bone morphogenetic protein receptor type II" EXACT []
xref: IUPHARobj:1794
xref: PIRSF:PIRSF500434
is_a: PR:000000007 ! TGF-beta superfamily receptor type-2 with activin receptor domain