[Term]
id: PR:000000035
name: BMP receptor type-1A
def: "A TGF-beta superfamily receptor type-1 that is a translation product of the human BMPR1A gene or a 1:1 ortholog thereof. Bone morphogenetic protein (BMP) signals are transmitted by type 2 and type 1 serine/threonine kinase receptors. Type 2 receptors phosphorylate and activate type 1 receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2 and BMP4." [PRO:CNA]
comment: Category=gene.
synonym: "ALK3" RELATED Gene-based []
synonym: "Bmpr" RELATED Gene-based []
synonym: "SKR5" EXACT []
synonym: "ALK-3" EXACT []
synonym: "CD292" EXACT []
synonym: "BMPR1A" EXACT PRO-short-label [PRO:DNx]
synonym: "ACVRLK3" RELATED Gene-based []
synonym: "BMPR-1A" EXACT []
synonym: "BMP type-1A receptor" EXACT []
synonym: "BMP-2/BMP-4 receptor" EXACT []
synonym: "activin receptor-like kinase 3" EXACT []
synonym: "serine/threonine-protein kinase receptor R5" EXACT []
xref: IUPHARobj:1786
is_a: PR:000000006 ! TGF-beta superfamily receptor type-1