[Term] id: PR:000000017 name: interferon gamma def: "A type II interferon that is a translation product of the human IFNG gene or a 1:1 ortholog thereof. The core domain structure consists of an Interferon gamma domain (Pfam:PF00714) that is four-helical cytokine domain with an additional helix in one of the crossover connections. It is a cytokine produced by lymphocytes activated by specific antigens or mitogens that has important immunoregulatory functions." [PRO:CNA] comment: Category=gene. synonym: "IFNG" EXACT PRO-short-label [PRO:DNx] synonym: "IFN-gamma" EXACT [] synonym: "immune interferon" EXACT [] xref: PIRSF:PIRSF001936 is_a: PR:000024990 ! type II interferon [Term] id: PR:P49708 name: interferon gamma (chicken) def: "An interferon gamma that is encoded in the genome of chicken." [OMA:P49708, PANTHER:PTHR11419:SF0, PRO:DNx] comment: Category=organism-gene. synonym: "IFNG" RELATED Gene-based [UniProtKB:P49708] synonym: "chick-IFNG" EXACT PRO-short-label [PRO:DNx] synonym: "IFN-gamma (chicken)" EXACT [UniProtKB:P49708] xref: UniProtKB:P49708 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000000017 ! interferon gamma relationship: has_gene_template NCBIGene:396054 ! IFNG (chicken)