[Term]
id: PR:P01579
name: interferon gamma (human)
def: "An interferon gamma that is encoded in the genome of human." [PRO:CNA, UniProtKB:P01579]
comment: Category=organism-gene.
synonym: "IFNG" RELATED Gene-based [UniProtKB:P01579]
synonym: "hIFNG" EXACT PRO-short-label [PRO:DNx]
synonym: "IFN-gamma (human)" EXACT [UniProtKB:P01579]
synonym: "immune interferon (human)" EXACT [UniProtKB:P01579]
xref: UniProtKB:P01579
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000017 ! interferon gamma
relationship: has_gene_template HGNC:5438 ! IFNG (human)

[Term]
id: PR:P01579-1
name: interferon gamma isoform 1 (human)
def: "An interferon gamma isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hIFNG/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01579-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000100 ! interferon gamma isoform 1

[Term]
id: PR:000036420
name: interferon gamma isoform 1 cleaved and N-glycosylated 2 (human)
def: "An interferon gamma isoform 1 cleaved and N-glycosylated 2 in human. UniProtKB:P01579-1, 24-161, Asn-48/Asn-120, MOD:00160." [PMID:1902591, PMID:6427223, PRO:CNA]
comment: Category=organism-modification.
synonym: "hIFNG/iso:1/ClvNGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000016444, Asn-48/Asn-120, MOD:00160" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P01579-1, 24-161, Asn-48/Asn-120, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000447 ! interferon gamma isoform 1 cleaved and N-glycosylated 2
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine

[Term]
id: PR:000000017
name: interferon gamma
def: "A type II interferon that is a translation product of the human IFNG gene or a 1:1 ortholog thereof. The core domain structure consists of an Interferon gamma domain (Pfam:PF00714) that is four-helical cytokine domain with an additional helix in one of the crossover connections. It is a cytokine produced by lymphocytes activated by specific antigens or mitogens that has important immunoregulatory functions." [PRO:CNA]
comment: Category=gene.
synonym: "IFNG" EXACT PRO-short-label [PRO:DNx]
synonym: "IFN-gamma" EXACT []
synonym: "immune interferon" EXACT []
xref: PIRSF:PIRSF001936
is_a: PR:000024990 ! type II interferon

[Term]
id: PR:000036419
name: interferon gamma isoform 1, signal peptide removed N-glycosylated 1 (human)
def: "An interferon gamma isoform 1, signal peptide removed glycosylated form in human in which N-linked glycosylation occurs at Asn-48 and Asn-120. UniProtKB:P01579-1, 24-157, Asn-48/Asn-120, MOD:00160." [PMID:10986460, PMID:3109913, PMID:6427223, PRO:CNA, PRO:DAN]
comment: Category=organism-modification.
synonym: "hIFNG/iso:1/SigPep-/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P01579-1, 24-157, Asn-48/Asn-120, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:000000446 ! interferon gamma isoform 1, signal peptide removed glycosylated form
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens